(Q34572232)

3 August 2017

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title

Transforming growth factor-beta in T-cell biology (English)

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3 August 2017

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Leonid Gorelik

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3 August 2017

Richard A Flavell

series ordinal

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3 August 2017

publication date

1 January 2002

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Nature Reviews Immunology

3 August 2017

published in

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3 August 2017

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3 August 2017

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3 August 2017

page(s)

46-53

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Targeted disruption of the mouse transforming growth factor-beta 1 gene results in multifocal inflammatory disease

3 August 2017

cites work

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Transforming growth factor beta 1 null mutation in mice causes excessive inflammatory response and early death

31 March 2020

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Abnormal lung development and cleft palate in mice lacking TGF-beta 3 indicates defects of epithelial-mesenchymal interaction

31 March 2020

1 reference

Transforming growth factor-beta 3 is required for secondary palate fusion

31 March 2020

1 reference

Susceptibility and resistance of human autoimmune T cell activation to the immunoregulatory effects of transforming growth factor (TGF) beta 1, beta 2, and beta 1.2.

31 March 2020

1 reference

Production of transforming growth factor beta by human T lymphocytes and its potential role in the regulation of T cell growth

31 March 2020

1 reference

Transforming growth factor beta and cyclosporin A inhibit the inducible activity of the interleukin-2 gene in T cells through a noncanonical octamer-binding site

31 March 2020

1 reference

p15INK4B is a potential effector of TGF-beta-induced cell cycle arrest

31 March 2020

1 reference

Transforming growth factor beta induces the cyclin-dependent kinase inhibitor p21 through a p53-independent mechanism

31 March 2020

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p27Kip1, a cyclin-Cdk inhibitor, links transforming growth factor-beta and contact inhibition to cell cycle arrest

31 March 2020

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Selective inhibition of growth-related gene expression in murine keratinocytes by transforming growth factor beta

31 March 2020

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Inhibition of cytotoxic T cell development by transforming growth factor beta and reversal by recombinant tumor necrosis factor alpha

31 March 2020

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31 March 2020

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Identification of Smad7, a TGFbeta-inducible antagonist of TGF-beta signalling

31 March 2020

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Inhibition of transforming growth factor-beta/SMAD signalling by the interferon-gamma/STAT pathway.

31 March 2020

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Interferon gamma signaling alters the function of T helper type 1 cells.

31 March 2020

1 reference

31 March 2020

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The effect of TGF-beta1 on immune responses of naïve versus memory CD4+ Th1/Th2 T cells

31 March 2020

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Cutting edge: TGF-beta inhibits Th type 2 development through inhibition of GATA-3 expression.

31 March 2020

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TGF-β1 down-regulates Th2 development and results in decreased IL-4-induced STAT6 activation and GATA-3 expression

31 March 2020

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The transcription factor GATA-3 is necessary and sufficient for Th2 cytokine gene expression in CD4 T cells

31 March 2020

1 reference

A novel transcription factor, T-bet, directs Th1 lineage commitment

31 March 2020

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Role of T-bet in commitment of TH1 cells before IL-12-dependent selection.

31 March 2020

1 reference

Vertebrate mesendoderm induction and patterning

31 March 2020

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Two subsets of memory T lymphocytes with distinct homing potentials and effector functions

31 March 2020

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Control of CD4 effector fate: transforming growth factor beta 1 and interleukin 2 synergize to prevent apoptosis and promote effector expansion

31 March 2020

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Transforming growth factor beta1 inhibits Fas ligand expression and subsequent activation-induced cell death in T cells via downregulation of c-Myc

31 March 2020

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Abrogation of TGFbeta signaling in T cells leads to spontaneous T cell differentiation and autoimmune disease

31 March 2020

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Transforming growth factor beta 1 (TGF-beta 1) controls expression of major histocompatibility genes in the postnatal mouse: aberrant histocompatibility antigen expression in the pathogenesis of the TGF-beta 1 null mouse phenotype

31 March 2020

1 reference

Disruption of T cell homeostasis in mice expressing a T cell-specific dominant negative transforming growth factor beta II receptor

31 March 2020

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Blockade of transforming growth factor beta/Smad signaling in T cells by overexpression of Smad7 enhances antigen-induced airway inflammation and airway reactivity

31 March 2020

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In vivo and in vitro clonal deletion of double-positive thymocytes

31 March 2020

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RAG-1-deficient mice have no mature B and T lymphocytes

31 March 2020

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Blocking Smad7 restores TGF-beta1 signaling in chronic inflammatory bowel disease

31 March 2020

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Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn's disease

31 March 2020

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A frameshift mutation in NOD2 associated with susceptibility to Crohn's disease

31 March 2020

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Cell contact-dependent immunosuppression by CD4(+)CD25(+) regulatory T cells is mediated by cell surface-bound transforming growth factor beta

31 March 2020

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Immunologic self-tolerance maintained by CD25+CD4+ naturally anergic and suppressive T cells: induction of autoimmune disease by breaking their anergic/suppressive state

31 March 2020

1 reference

Regulatory T cells in autoimmmunity*.

31 March 2020

1 reference

Regulatory T cells: key controllers of immunologic self-tolerance

31 March 2020

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A critical role for transforming growth factor-beta but not interleukin 4 in the suppression of T helper type 1-mediated colitis by CD45RB(low) CD4+ T cells

31 March 2020

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CD4+CD25+ immunoregulatory T cells suppress polyclonal T cell activation in vitro by inhibiting interleukin 2 production

31 March 2020

1 reference

A receptor for phosphatidylserine-specific clearance of apoptotic cells

31 March 2020

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Natural adjuvants: endogenous activators of dendritic cells

31 March 2020

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TGF-beta released by apoptotic T cells contributes to an immunosuppressive milieu

31 March 2020

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Localization of transforming growth factor-beta 1 in mitochondria of murine heart and liver

31 March 2020

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Modulation of macrophage function by transforming growth factor beta, interleukin-4, and interleukin-10.

31 March 2020

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Control of nitric oxide synthase expression by transforming growth factor-beta: implications for homeostasis

31 March 2020

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Contrasting effects of TGF-beta 1 and TNF-alpha on the development of dendritic cells from progenitors in mouse bone marrow

31 March 2020

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Dendritic cells: specialized and regulated antigen processing machines

31 March 2020

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TGF-beta1 inhibits protracted-relapsing experimental autoimmune encephalomyelitis by activating dendritic cells

31 March 2020

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TGF-beta receptor controls B cell responsiveness and induction of IgA in vivo

31 March 2020

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Role of transforming growth factor beta in cancer

31 March 2020

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Transforming growth factor beta secretion from primary breast cancer fibroblasts

31 March 2020

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Immune-mediated eradication of tumors through the blockade of transforming growth factor-beta signaling in T cells

31 March 2020

1 reference

How cells read TGF-beta signals

31 March 2020

1 reference

Helicobacter hepaticus triggers colitis in specific-pathogen-free interleukin-10 (IL-10)-deficient mice through an IL-12- and gamma interferon-dependent mechanism

31 March 2020

1 reference

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/NRI704

1 reference

Dimensions Publication ID

3 August 2017

1030677337

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