(Q34561057)

3 August 2017

title

L1 retrotransposition is suppressed by endogenously encoded small interfering RNAs in human cultured cells (English)

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3 August 2017

Nuo Yang

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3 August 2017

Haig H Kazazian

series ordinal

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3 August 2017

publication date

27 August 2006

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Nature Structural & Molecular Biology

3 August 2017

published in

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3 August 2017

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3 August 2017

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3 August 2017

page(s)

763-771

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Initial sequencing and analysis of the human genome

3 August 2017

cites work

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Biology of mammalian L1 retrotransposons

21 January 2018

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Mobile elements: drivers of genome evolution

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Human L1 retrotransposition: cis preference versus trans complementation

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Cis-preferential LINE-1 reverse transcriptase activity in ribonucleoprotein particles

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Sequence-specific single-strand RNA binding protein encoded by the human LINE-1 retrotransposon

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Nucleic acid chaperone activity of the ORF1 protein from the mouse LINE-1 retrotransposon

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Human L1 retrotransposon encodes a conserved endonuclease required for retrotransposition

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High frequency retrotransposition in cultured mammalian cells

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Reverse Transcriptase Encoded by a Human Transposable Element

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Reverse transcription of R2Bm RNA is primed by a nick at the chromosomal target site: A mechanism for non-LTR retrotransposition

21 January 2018

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Exon shuffling by L1 retrotransposition

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DNA repair mediated by endonuclease-independent LINE-1 retrotransposition

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RNA-directed transcriptional gene silencing in mammals

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Regulation of apoptosis by alternative pre-mRNA splicing

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Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans

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RNAi: double-stranded RNA directs the ATP-dependent cleavage of mRNA at 21 to 23 nucleotide intervals

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Role for a bidentate ribonuclease in the initiation step of RNA interference

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Single-stranded antisense siRNAs guide target RNA cleavage in RNAi

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Role of transposable elements in heterochromatin and epigenetic control

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The rde-1 gene, RNA interference, and transposon silencing in C. elegans

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Mut-7 of C. elegans, required for transposon silencing and RNA interference, is a homolog of Werner syndrome helicase and RNaseD.

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Dicer-deficient mouse embryonic stem cells are defective in differentiation and centromeric silencing

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Identification, characterization, and cell specificity of a human LINE-1 promoter

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Antisense promoter of human L1 retrotransposon drives transcription of adjacent cellular genes

21 January 2018

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Many human genes are transcribed from the antisense promoter of L1 retrotransposon

21 January 2018

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A YY1-binding site is required for accurate human LINE-1 transcription initiation

21 January 2018

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The human L1 promoter: variable transcription initiation sites and a major impact of upstream flanking sequence on promoter activity

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Passenger-strand cleavage facilitates assembly of siRNA into Ago2-containing RNAi enzyme complexes

21 January 2018

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Determination of L1 retrotransposition kinetics in cultured cells

21 January 2018

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Members of the SRY family regulate the human LINE retrotransposons

21 January 2018

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An important role for RUNX3 in human L1 transcription and retrotransposition

21 January 2018

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Antisense transcription in the mammalian transcriptome

21 January 2018

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Accurate positioning of RNA polymerase II on a natural TATA-less promoter is independent of TATA-binding-protein-associated factors and initiator-binding proteins

21 January 2018

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The serotonin 1a receptor gene contains a TATA-less promoter that responds to MAZ and Sp1

21 January 2018

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A potential role for RNA interference in controlling the activity of the human LINE-1 retrotransposon

21 January 2018

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Dicer is essential for mouse development

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Argonaute2 is the catalytic engine of mammalian RNAi

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Molecular evolution and tempo of amplification of human LINE-1 retrotransposons since the origin of primates.

21 January 2018

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Elucidation of the small RNA component of the transcriptome

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Generation of Ski-knockdown mice by expressing a long double-strand RNA from an RNA polymerase II promoter.

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Specific and potent RNAi in the nucleus of human cells

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Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells

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Meiotic catastrophe and retrotransposon reactivation in male germ cells lacking Dnmt3L

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Methyl-CpG-binding protein 2 represses LINE-1 expression and retrotransposition but not Alu transcription

21 January 2018

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RNA truncation by premature polyadenylation attenuates human mobile element activity

21 January 2018

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Transcriptional disruption by the L1 retrotransposon and implications for mammalian transcriptomes

21 January 2018

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Identification and characterization of two novel classes of small RNAs in the mouse germline: retrotransposon-derived siRNAs in oocytes and germline small RNAs in testes

21 January 2018

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L1 retrotransposon-mediated stable gene silencing

21 January 2018

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A SANT motif in the SMRT corepressor interprets the histone code and promotes histone deacetylation

21 January 2018

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Transposon silencing in the Caenorhabditis elegans germ line by natural RNAi

21 January 2018

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Selection against deleterious LINE-1-containing loci in the human lineage

21 January 2018

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RNAi and expression of retrotransposons MuERV-L and IAP in preimplantation mouse embryos

31 March 2020

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Identification of critical CpG sites for repression of L1 transcription by DNA methylation

31 March 2020

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31 March 2020

Identifiers

DOI

10.1038/NSMB1141

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3 August 2017

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