(Q34551341)

3 August 2017

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title

Unlocking the immunological mechanisms of orbital inflammation in thyroid eye disease (English)

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3 August 2017

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M Ludgate

2 references

ORCID Public Data File 2021

3 August 2017

G Baker

1 reference

3 August 2017

publication date

1 February 2002

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Clinical and Experimental Immunology

3 August 2017

published in

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3 August 2017

volume

127

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3 August 2017

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3 August 2017

page(s)

193-198

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Autoantibodies to the thyrotropin receptor

3 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2249.2002.01792.X

The thyrotropin receptor in thyroid diseases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2249.2002.01792.X

Thyroid-associated ophthalmopathy: pathogenesis and clinical management.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2249.2002.01792.X

Muscle autoantigens in thyroid associated ophthalmopathy: the limits of molecular genetics

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2249.2002.01792.X

Cloning and sequencing of a novel 64-kDa autoantigen recognized by patients with autoimmune thyroid disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2249.2002.01792.X

Definition, at the molecular level, of a thyroglobulin-acetylcholinesterase shared epitope: study of its pathophysiological significance in patients with Graves' ophthalmopathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2249.2002.01792.X

Thyrotropin receptors in adipose tissue, retro-orbital tissue and lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2249.2002.01792.X

Comparison of the Effects of Thyrotropin and the Long-Acting Thyroid Stimulator on Guinea Pig Adipose Tissue

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2249.2002.01792.X

Retrobulbar modifications in experimental exophthalmos: the effect of thyrotropin and an exophthalmos producing substance derived from thyrotropin on the 35SO4 incorporation and glycosaminoglycan content of Harderian glands

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2249.2002.01792.X

Stabilization, partial purification, and characterization of thyrotropin receptors in solubilized guinea pig fat cell membranes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2249.2002.01792.X

Thyrotropin interactions with human fat cell membrane preparations and the finding of a soluble thyrotropin binding component

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2249.2002.01792.X

Regulation of lipolysis during the neonatal period. Importance of thyrotropin

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2249.2002.01792.X

Cloning and functional expression of a thyrotropin receptor cDNA from rat fat cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2249.2002.01792.X

Functional expression of thyrotropin receptor in differentiated 3T3-L1 cells: a possible model cell line of extrathyroidal expression of thyrotropin receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2249.2002.01792.X

Analysis of differentiation-induced expression mechanisms of thyrotropin receptor gene in adipocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2249.2002.01792.X

Current evidence for and against the TSH receptor being the common antigen in Graves' disease and thyroid associated ophthalmopathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2249.2002.01792.X

Is Graves' Dermopathy a Generalized Disorder?

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2249.2002.01792.X

Genetic immunization of outbred mice with thyrotropin receptor cDNA provides a model of Graves' disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2249.2002.01792.X

CD30-mediated signaling promotes the development of human T helper type 2-like T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2249.2002.01792.X

HMC-1 mast cells activate human orbital fibroblasts in coculture: evidence for up-regulation of prostaglandin E2 and hyaluronan synthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2249.2002.01792.X

An elevation of stem cell factor in patients with hyperthyroid Graves' disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2249.2002.01792.X

Induction of human IgE synthesis in B cells by mast cells and basophils

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2249.2002.01792.X

Elevated expressionin situof selectin and immunoglobulin superfamily type adhesion molecules in retroocular connective tissues from patients with Graves' ophthalmopathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2249.2002.01792.X

Cultured human fibroblasts express constitutive IL-16 mRNA: cytokine induction of active IL-16 protein synthesis through a caspase-3-dependent mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2249.2002.01792.X

Increased induction of HLA-DR by interferon-gamma in cultured fibroblasts derived from patients with Graves' ophthalmopathy and pretibial dermopathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2249.2002.01792.X

Detection, cellular localization, and modulation of heat shock proteins in cultured fibroblasts from patients with extrathyroidal manifestations of Graves' disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2249.2002.01792.X

Stimulation of extraocular muscle fibroblasts by cytokines and hypoxia: possible role in thyroid-associated ophthalmopathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2249.2002.01792.X

Autoantibodies against Forssman glycolipids in Graves' disease and Hashimoto's thyroiditis

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2249.2002.01792.X

Human mast cells augment fibroblast proliferation by heterotypic cell-cell adhesion and action of IL-4.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1906338

Human orbital fibroblasts are activated through CD40 to induce proinflammatory cytokine production.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1906338

Soluble Interleukin-1 Receptor Antagonist Serum Levels in Smokers and Nonsmokers with Graves’ Ophthalmopathy Undergoing Orbital Radiotherapy1

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1906338

Transfer of thyroiditis, with syngeneic spleen cells sensitized with the human thyrotropin receptor, to naive BALB/c and NOD mice

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1906338

Autoimmune thyroid disease: further developments in our understanding

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1906338

Coculture of mouse IL-3-dependent mast cells with 3T3 fibroblasts stimulates synthesis of globopentaosylceramide (Forssman glycolipid) by fibroblasts and surface expression on both populations.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1906338

Thyrotropin receptor messenger ribonucleic acid is expressed in most brown and white adipose tissues in the guinea pig

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1906338

Activation of human orbital fibroblasts through CD40 engagement results in a dramatic induction of hyaluronan synthesis and prostaglandin endoperoxide H synthase-2 expression. Insights into potential pathogenic mechanisms of thyroid-associated ophth

27 October 2018

1 reference

12 December 2020

Cytokine profiles in eye muscle tissue and orbital fat tissue from patients with thyroid-associated ophthalmopathy

1 reference

12 December 2020

Soluble interleukin-1 receptor antagonist concentration in patients with Graves' ophthalmopathy is neither related to cigarette smoking nor predictive of subsequent response to glucocorticoids

1 reference

12 December 2020

Functional TSH receptor in human abdominal preadipocytes and orbital fibroblasts

1 reference

12 December 2020

Serum concentrations of proinflammatory cytokines in Graves' disease: effect of treatment, thyroid function, ophthalmopathy and cigarette smoking

1 reference

12 December 2020

Both Th1- and Th2-derived cytokines in serum are elevated in Graves' ophthalmopathy

1 reference

12 December 2020

Thyrotropin receptor transcripts in human adipose tissue

1 reference

12 December 2020

Adipogenesis in thyroid eye disease

1 reference

12 December 2020

Serum antibodies against the flavoprotein subunit of succinate dehydrogenase are sensitive markers of eye muscle autoimmunity in patients with Graves' hyperthyroidism

1 reference

12 December 2020

Development of an animal model of autoimmune thyroid eye disease

1 reference

12 December 2020

Autoantibodies reactive with extracellular matrix proteins in patients with thyroid-associated ophthalmopathy

1 reference

12 December 2020

Dominant infiltration of T(H)1-type CD4+ T cells at the retrobulbar space of patients with thyroid-associated ophthalmopathy

1 reference

12 December 2020

Differentiation of human orbital preadipocyte fibroblasts induces expression of functional thyrotropin receptor

1 reference

12 December 2020

The effect of cigarette smoke constituents on the expression of HLA-DR in orbital fibroblasts derived from patients with Graves ophthalmopathy

1 reference

12 December 2020

A possible role of immunoglobulin E in patients with hyperthyroid Graves' disease

1 reference

12 December 2020

Pulsed monoclonal antibody treatment and autoimmune thyroid disease in multiple sclerosis

1 reference

12 December 2020

The combination of absent thyroid peroxidase antibodies and high thyroid-stimulating immunoglobulin levels in Graves' disease identifies a group at markedly increased risk of ophthalmopathy

1 reference

12 December 2020

Relationship between disease duration and predominant orbital T cell subset in Graves' ophthalmopathy

1 reference

12 December 2020

Immunohistochemical and Ultrastructural Studies on the Exenterated Orbital Tissues of a Patient with Graves' Disease

1 reference

12 December 2020

Homology between thyroglobulin and acetylcholinesterase: an explanation for pathogenesis of Graves' ophthalmopathy?

1 reference

12 December 2020

Antibodies to porcine eye muscle in patients with Graves' ophthalmopathy: identification of serum immunoglobulins directed against unique determinants by immunoblotting and enzyme-linked immunosorbent assay

1 reference

12 December 2020

Presence of antibodies in the sera of patients with Graves' disease recognizing a 23 kilodalton fibroblast protein

1 reference

12 December 2020

Stimulation of glycosaminoglycan accumulation by interferon gamma in cultured human retroocular fibroblasts

1 reference

12 December 2020

Graves' immunoglobulins and cytokines stimulate the expression of intercellular adhesion molecule-1 (ICAM-1) in cultured Graves' orbital fibroblasts

1 reference

12 December 2020

Detection and localization of cytokine immunoreactivity in retro-ocular connective tissue in Graves' ophthalmopathy

1 reference

12 December 2020

Expression of thyrotropin-receptor mRNA in healthy and Graves' disease retro-orbital tissue

1 reference

12 December 2020

Demonstration of thyrotropin binding sites in orbital connective tissue: possible role in the pathogenesis of thyroid-associated ophthalmopathy

1 reference

12 December 2020

Human histocompatibility leukocyte antigen-DR and heat shock protein-70 expression in eye muscle tissue in thyroid-associated ophthalmopathy

1 reference

12 December 2020

Differentiation of rat preadipocytes is accompanied by expression of thyrotropin receptors

1 reference

12 December 2020

Evidence of adipocyte differentiation in human orbital fibroblasts in primary culture

1 reference

12 December 2020

Leukoregulin induction of prostaglandin-endoperoxide H synthase-2 in human orbital fibroblasts. An in vitro model for connective tissue inflammation

1 reference

12 December 2020

Smoking and endocrine ophthalmopathy: impact of smoking severity and current vs lifetime cigarette consumption

1 reference

12 December 2020

Adhesion molecule expression in vivo on extraocular muscles (EOM) in thyroid-associated ophthalmopathy (TAO)

1 reference

12 December 2020

HPLC glycosaminoglycan analysis in patients with Graves' disease

1 reference

12 December 2020

Increased serum concentration of soluble CD30 in patients with Graves' disease and Hashimoto's thyroiditis

1 reference

12 December 2020

Analysis of human thyrotropin receptor gene expression and immunoreactivity in human orbital tissue

1 reference

12 December 2020

Anti-heat shock protein (hsp)72 antibodies are present in patients with Graves' disease (GD) and in smoking control subjects

1 reference

12 December 2020

Thyrotropin receptor expression in Graves' orbital adipose/connective tissues: potential autoantigen in Graves' ophthalmopathy

1 reference

12 December 2020

Presence of thyrotropin receptor in infant adipocytes.

1 reference

12 December 2020

Interleukin-8 and monocyte chemotactic protein-1 gene expression and protein production by human orbital fibroblasts

1 reference

12 December 2020

10.1046/J.1365-2249.2002.01792.X

Identifiers

DOI

1 reference

3 August 2017

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