(Q34535610)

2 August 2017

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title

Transcriptional silencing at Saccharomyces telomeres: implications for other organisms (English)

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2 August 2017

Wai-Hong Tham

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2 August 2017

Virginia A Zakian

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2 August 2017

language of work or name

English

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publication date

1 January 2002

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2 August 2017

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inferred from page(s)

published in

Oncogene

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2 August 2017

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2 August 2017

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2 August 2017

page(s)

512-521

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Perinuclear localization of chromatin facilitates transcriptional silencing

2 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205078

Modifiers of position effect are shared between telomeric and silent mating-type loci in S. cerevisiae.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205078

Overcoming telomeric silencing: a trans-activator competes to establish gene expression in a cell cycle-dependent way.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205078

Telomere position effect in human cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205078

ATP-dependent recognition of eukaryotic origins of DNA replication by a multiprotein complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205078

A positive selection for mutants lacking orotidine-5'-phosphate decarboxylase activity in yeast: 5-fluoro-orotic acid resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205078

Components of the Ku-dependent non-homologous end-joining pathway are involved in telomeric length maintenance and telomeric silencing

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205078

Sir proteins, Rif proteins, and Cdc13p bind Saccharomyces telomeres in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205078

The SIR2 gene family, conserved from bacteria to humans, functions in silencing, cell cycle progression, and chromosome stability

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205078

Transcriptional silencing in yeast is associated with reduced nucleosome acetylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205078

The carboxy termini of Sir4 and Rap1 affect Sir3 localization: evidence for a multicomponent complex required for yeast telomeric silencing

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205078

Regulation of telomere length and function by a Myb-domain protein in fission yeast

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205078

Fission yeast Taz1 protein is required for meiotic telomere clustering and recombination.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205078

Involvement of the checkpoint protein Mec1p in silencing of gene expression at telomeres in Saccharomyces cerevisiae

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205078

Silencing at Drosophila telomeres: nuclear organization and chromatin structure play critical roles

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205078

Effects of DNA nonhomologous end-joining factors on telomere length and chromosomal stability in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205078

Telomere folding is required for the stable maintenance of telomere position effects in yeast

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205078

Malaria. Cooperative silencing elements in var genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205078

Cohabitation of insulators and silencing elements in yeast subtelomeric regions

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205078

Frequent ectopic recombination of virulence factor genes in telomeric chromosome clusters of P. falciparum

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205078

Cell cycle-dependent specific positioning and clustering of centromeres and telomeres in fission yeast

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205078

Distortion of the DNA double helix by RAP1 at silencers and multiple telomeric binding sites.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205078

beta-D-glucosyl-hydroxymethyluracil: a novel modified base present in the DNA of the parasitic protozoan T. brucei

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205078

The clustering of telomeres and colocalization with Rap1, Sir3, and Sir4 proteins in wild-type Saccharomyces cerevisiae

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205078

Localization of Sir2p: the nucleolus as a compartment for silent information regulators

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205078

A new role for a yeast transcriptional silencer gene, SIR2, in regulation of recombination in ribosomal DNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205078

Telomere-proximal DNA in Saccharomyces cerevisiae is refractory to methyltransferase activity in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205078

Position effect at S. cerevisiae telomeres: reversible repression of Pol II transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205078

Mammalian telomeres end in a large duplex loop

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205078

Sir-Ku-itous routes to make ends meet

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205078

A RAP1-interacting protein involved in transcriptional silencing and telomere length regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205078

Histone H3 and H4 N-termini interact with SIR3 and SIR4 proteins: a molecular model for the formation of heterochromatin in yeast

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205078

Spreading of transcriptional repressor SIR3 from telomeric heterochromatin

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205078

Genetic manipulation of centromere function

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205078

A developmentally regulated position effect at a telomeric locus in Trypanosoma brucei.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205078

Ku is associated with the telomere in mammals

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205078

Ku acts in a unique way at the mammalian telomere to prevent end joining

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205078

The ubiquitin-conjugating enzyme Rad6 (Ubc2) is required for silencing in Saccharomyces cerevisiae

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205078

Transcriptional silencing and longevity protein Sir2 is an NAD-dependent histone deacetylase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205078

The SIR2/3/4 complex and SIR2 alone promote longevity in Saccharomyces cerevisiae by two different mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205078

Redistribution of silencing proteins from telomeres to the nucleolus is associated with extension of life span in S. cerevisiae.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205078

C-terminal truncation of RAP1 results in the deregulation of telomere size, stability, and function in Saccharomyces cerevisiae

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205078

RAP1 and telomere structure regulate telomere position effects in Saccharomyces cerevisiae.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205078

Disturbance of normal cell cycle progression enhances the establishment of transcriptional silencing in Saccharomyces cerevisiae

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205078

Mutation of yeast Ku genes disrupts the subnuclear organization of telomeres

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205078

Effects of genomic position on the expression of transduced copies of the white gene of Drosophila.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205078

Identification of human Rap1: implications for telomere evolution

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205078

The Saccharomyces CDC13 protein is a single-strand TG1-3 telomeric DNA-binding protein in vitro that affects telomere behavior in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205078

The chromosome ends of Saccharomyces cerevisiae.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205078

Repair of chromosome ends after telomere loss in Saccharomyces

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205078

Relocalization of telomeric Ku and SIR proteins in response to DNA strand breaks in yeast

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205078

The unusual telomeres of Drosophila.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205078

DNA damage triggers disruption of telomeric silencing and Mec1p-dependent relocation of Sir3p

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205078

MEC1-dependent redistribution of the Sir3 silencing protein from telomeres to DNA double-strand breaks

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205078

Yeast Ku protein plays a direct role in telomeric silencing and counteracts inhibition by rif proteins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205078

The yeast Cac1 protein is required for the stable inheritance of transcriptionally repressed chromatin at telomeres

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205078

Evidence that a complex of SIR proteins interacts with the silencer and telomere-binding protein RAP1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205078

t-loops at trypanosome telomeres.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205078

Telomeres of polytene chromosomes in a ciliated protozoan terminate in duplex DNA loops

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205078

Defective meiosis in telomere-silencing mutants of Schizosaccharomyces pombe

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205078

Cdc13p: a single-strand telomeric DNA-binding protein with a dual role in yeast telomere maintenance

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205078

SIR3 and SIR4 proteins are required for the positioning and integrity of yeast telomeres

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205078

Limitations of silencing at native yeast telomeres

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205078

Changing the end: antigenic variation orchestrated at the telomeres of African trypanosomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205078

TEL2, an essential gene required for telomere length regulation and telomere position effect in Saccharomyces cerevisiae

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205078

Schizosaccharomyces pombe and Saccharomyces cerevisiae: a look at yeasts divided

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205078

Mammalian Ku86 protein prevents telomeric fusions independently of the length of TTAGGG repeats and the G-strand overhang

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205078

Transcription of a yeast telomere alleviates telomere position effect without affecting chromosome stability

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205078

Antigenic variation in malaria: in situ switching, relaxed and mutually exclusive transcription of var genes during intra-erythrocytic development in Plasmodium falciparum

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205078

Transcription interferes with elements important for chromosome maintenance in Saccharomyces cerevisiae

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205078

SIR2 and SIR4 interactions differ in core and extended telomeric heterochromatin in yeast

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205078

GFP tagging of budding yeast chromosomes reveals that protein-protein interactions can mediate sister chromatid cohesion

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205078

An enzymatic activity in the yeast Sir2 protein that is essential for gene silencing

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205078

Increased dosage of a sir-2 gene extends lifespan in Caenorhabditis elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205078

beta-D-glucosyl-hydroxymethyluracil is a conserved DNA modification in kinetoplastid protozoans and is abundant in their telomeres

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205078

Telomeric silencing of a natural subtelomeric gene.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205078

A novel Rap1p-interacting factor, Rif2p, cooperates with Rif1p to regulate telomere length in Saccharomyces cerevisiae.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205078

Saccharomyces telomeres assume a non-nucleosomal chromatin structure

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205078

Protein-DNA interactions in soluble telosomes from Saccharomyces cerevisiae

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205078

Chromosomal landscape of nucleosome-dependent gene expression and silencing in yeast.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205078

Structure, function, and replication of Saccharomyces cerevisiae telomeres

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205078

Cell-cycle-regulated association of RAD50/MRE11/NBS1 with TRF2 and human telomeres

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205078

The Saccharomyces retrotransposon Ty5 integrates preferentially into regions of silent chromatin at the telomeres and mating loci

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205078

Telomere looping permits gene activation by a downstream UAS in yeast

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205078

Action of a RAP1 carboxy-terminal silencing domain reveals an underlying competition between HMR and telomeres in yeast

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205078

7 January 2021

A family of Saccharomyces cerevisiae repetitive autonomously replicating sequences that have very similar genomic environments

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205078

7 January 2021

Organization of DNA sequences and replication origins at yeast telomeres

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205078

7 January 2021

RAP1 protein interacts with yeast telomeres in vivo: overproduction alters telomere structure and decreases chromosome stability

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205078

7 January 2021

Yeast Ku as a regulator of chromosomal DNA end structure

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205078

7 January 2021

Role of NAD(+) in the deacetylase activity of the SIR2-like proteins

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205078

7 January 2021

The Dynamics of Yeast Telomeres and Silencing Proteins through the Cell Cycle

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205078

7 January 2021

Evidence for silencing compartments within the yeast nucleus: a role for telomere proximity and Sir protein concentration in silencer-mediated repression

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205078

7 January 2021

Silencing of genes at nontelomeric sites in yeast is controlled by sequestration of silencing factors at telomeres by Rap 1 protein

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205078

7 January 2021

Silent domains are assembled continuously from the telomere and are defined by promoter distance and strength, and by SIR3 dosage

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205078

7 January 2021

Loss of a yeast telomere: arrest, recovery, and chromosome loss.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205078

7 January 2021

Internal tracts of telomeric DNA act as silencers in Saccharomyces cerevisiae

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205078

7 January 2021

Localization of yeast telomeres to the nuclear periphery is separable from transcriptional repression and telomere stability functions

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205078

7 January 2021

The role of the Mre11-Rad50-Xrs2 complex in telomerase- mediated lengthening of Saccharomyces cerevisiae telomeres

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205078

7 January 2021

Telomeric transcriptional silencing in a natural context

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205078

7 January 2021

Chromosome aberrations in desmoid tumors. Trisomy 8 may be a predictor of recurrence

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205078

7 January 2021

Telomere positional effects and the regulation of cellular senescence

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205078

7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1205078

1 reference

Dimensions Publication ID

2 August 2017

1038906484

0 references

1 reference