(Q34524540)

2 August 2017

title

Order-disorder transitions govern kinetic cooperativity and allostery of monomeric human glucokinase (English)

1 reference

2 August 2017

Mioara Larion

1 reference

2 August 2017

Roberto Kopke Salinas

1 reference

2 August 2017

Lei Bruschweiler-Li

1 reference

2 August 2017

Brian G Miller

1 reference

2 August 2017

Rafael Brüschweiler

1 reference

2 August 2017

language of work or name

English

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publication date

18 December 2012

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2 August 2017

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2 August 2017

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2 August 2017

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2 August 2017

page(s)

e1001452

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Creative Commons Attribution 4.0 International

2 August 2017

start time

18 December 2012

1 reference

April 2022 Public Data File from Crossref

copyrighted

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cites work

Thermal stability of glucokinase (GK) as influenced by the substrate glucose, an allosteric glucokinase activator drug (GKA) and the osmolytes glycerol and urea

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7 July 2018

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The active conformation of human glucokinase is not altered by allosteric activators

7 July 2018

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Crystal structure of E339K mutated human glucokinase reveals changes in the ATP binding site

7 July 2018

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Global Fit Analysis of Glucose Binding Curves Reveals a Minimal Model for Kinetic Cooperativity in Human Glucokinase

7 July 2018

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Direct evidence of conformational heterogeneity in human pancreatic glucokinase from high-resolution nuclear magnetic resonance

7 July 2018

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Determination of isoleucine side-chain conformations in ground and excited states of proteins from chemical shifts

7 July 2018

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Update on mutations in glucokinase (GCK), which cause maturity-onset diabetes of the young, permanent neonatal diabetes, and hyperinsulinemic hypoglycemia

7 July 2018

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Investigation of functionally liver selective glucokinase activators for the treatment of type 2 diabetes

7 July 2018

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Binding kinetics of glucose and allosteric activators to human glucokinase reveal multiple conformational states.

7 July 2018

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Assessing the potential of glucokinase activators in diabetes therapy

7 July 2018

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Discovery of novel 3,6-disubstituted 2-pyridinecarboxamide derivatives as GK activators

7 July 2018

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Identification of novel and potent 2-amino benzamide derivatives as allosteric glucokinase activators

7 July 2018

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Activating mutations in the human glucokinase gene revealed by genetic selection

7 July 2018

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7 July 2018

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Sensitivity of secondary structure propensities to sequence differences between alpha- and gamma-synuclein: implications for fibrillation

7 July 2018

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Glucose-induced conformational changes in glucokinase mediate allosteric regulation: transient kinetic analysis

7 July 2018

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The CCPN data model for NMR spectroscopy: development of a software pipeline

7 July 2018

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Intrinsically unstructured proteins and their functions

7 July 2018

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Structural basis for allosteric regulation of the monomeric allosteric enzyme human glucokinase

7 July 2018

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Two birds with one stone: novel glucokinase activator stimulates glucose-induced pancreatic insulin secretion and augments hepatic glucose metabolism

7 July 2018

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Glucokinase (GCK) mutations in hyper- and hypoglycemia: Maturity-onset diabetes of the young, permanent neonatal diabetes, and hyperinsulinemia of infancy

7 July 2018

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ON THE NATURE OF ALLOSTERIC TRANSITIONS: A PLAUSIBLE MODEL

7 July 2018

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Insights into the biochemical and genetic basis of glucokinase activation from naturally occurring hypoglycemia mutations

7 July 2018

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BAD and glucokinase reside in a mitochondrial complex that integrates glycolysis and apoptosis

7 July 2018

1 reference

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Regulation of β cell glucokinase by S-nitrosylation and association with nitric oxide synthase

7 July 2018

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Diabetes mellitus and genetically programmed defects in beta-cell function

7 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3525530

Characterization of glucokinase-binding protein epitopes by a phage-displayed peptide library. Identification of 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase as a novel interaction partner

7 July 2018

1 reference

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Genetics of neonatal hyperinsulinism.

7 July 2018

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Mutants of glucokinase cause hypoglycaemia- and hyperglycaemia syndromes and their analysis illuminates fundamental quantitative concepts of glucose homeostasis

7 July 2018

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NMRPipe: a multidimensional spectral processing system based on UNIX pipes

7 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3525530

The 13C chemical-shift index: a simple method for the identification of protein secondary structure using 13C chemical-shift data

7 July 2018

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New perspectives on pancreatic islet glucokinase

7 July 2018

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Comparison of Experimental Binding Data and Theoretical Models in Proteins Containing Subunits*

7 July 2018

1 reference

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Regulatory behavior of monomeric enzymes. 1. The mnemonical enzyme concept.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3525530

Escherichia coli aspartate transcarbamylase: the relation between structure and function

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3525530

Demonstration of a slow conformational change in liver glucokinase by fluorescence spectroscopy

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3525530

Observation of a kinetic slow transition in monomeric glucokinase

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3525530

Glucokinase as glucose sensor and metabolic signal generator in pancreatic beta-cells and hepatocytes

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3525530

Nonsense mutation in the glucokinase gene causes early-onset non-insulin-dependent diabetes mellitus

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3525530

Familial hyperinsulinism caused by an activating glucokinase mutation

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3525530

Severe persistent hyperinsulinemic hypoglycemia due to a de novo glucokinase mutation

28 July 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PBIO.1001452

Diagnostic difficulties in glucokinase hyperinsulinism.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PBIO.1001452

Activating glucokinase (GCK) mutations as a cause of medically responsive congenital hyperinsulinism: prevalence in children and characterisation of a novel GCK mutation

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PBIO.1001452

Heterogeneity in disease severity in a family with a novel G68V GCK activating mutation causing persistent hyperinsulinaemic hypoglycaemia of infancy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PBIO.1001452

Allosteric activators of glucokinase: potential role in diabetes therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PBIO.1001452

Expression and nitrogen-15 labeling of proteins for proton and nitrogen-15 nuclear magnetic resonance

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PBIO.1001452

23-Residue C-terminal alpha-helix governs kinetic cooperativity in monomeric human glucokinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PBIO.1001452

KineticDB: a database of protein folding kinetics.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PBIO.1001452

Insights in the (un)structural organization of Bacillus pasteurii UreG, an intrinsically disordered GTPase enzyme

21 January 2018

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3525530

27 October 2018

https://api.crossref.org/works/10.1371%2FJOURNAL.PBIO.1001452

Quantitative dynamics and binding studies of the 20S proteasome by NMR

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PBIO.1001452

A pre-steady state analysis of ligand binding to human glucokinase: evidence for a preexisting equilibrium

21 January 2018

1 reference

12 December 2020

Kinetic aspects of regulation of metabolic processes. The hysteretic enzyme concept

1 reference

12 December 2020

Transients and cooperativity. A slow transition model for relating transients and cooperative kinetics of enzymes

1 reference

12 December 2020

Allosteric activation of human glucokinase by free polyubiquitin chains and its ubiquitin-dependent cotranslational proteasomal degradation

1 reference

12 December 2020

10.1371/JOURNAL.PBIO.1001452

Identifiers

DOI

1 reference

2 August 2017

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2 August 2017

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