(Q34473449)

2 August 2017

title

Guanine nucleotide exchange factors regulate specificity of downstream signaling from Rac and Cdc42. (English)

1 reference

2 August 2017

1 reference

Zhou K

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2 August 2017

Wang Y

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2 August 2017

Gorski JL

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2 August 2017

Nomura N

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2 August 2017

Collard J

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2 August 2017

Bokoch GM

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2 August 2017

language of work or name

English

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publication date

1 July 1998

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Journal of Biological Chemistry

2 August 2017

published in

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2 August 2017

volume

273

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2 August 2017

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2 August 2017

page(s)

16782-16786

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Rho: a connection between membrane receptor signalling and the cytoskeleton

2 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.27.16782

Rho: theme and variations

21 January 2018

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Identification of a putative target for Rho as the serine-threonine kinase protein kinase N

21 January 2018

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Protein kinase N (PKN) and PKN-related protein rhophilin as targets of small GTPase Rho

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.273.27.16782

Wiskott-Aldrich syndrome protein, a novel effector for the GTPase CDC42Hs, is implicated in actin polymerization

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.273.27.16782

A brain serine/threonine protein kinase activated by Cdc42 and Rac1

21 January 2018

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Regulation of human leukocyte p21-activated kinases through G protein--coupled receptors

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.273.27.16782

Identification of a mouse p21Cdc42/Rac activated kinase

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.273.27.16782

The small GTP-binding proteins Rac1 and Cdc42 regulate the activity of the JNK/SAPK signaling pathway

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.273.27.16782

Selective activation of the JNK signaling cascadeand c-Jun transcriptional activity by the small GTPases Rac and Cdc42Hs

21 January 2018

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Rho Family GTPases Regulate p38 Mitogen-activated Protein Kinase through the Downstream Mediator Pak1

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.273.27.16782

The Dbl family of oncogenes

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.273.27.16782

Identification of an invasion-inducing gene, Tiam-1, that encodes a protein with homology to GDP-GTP exchangers for Rho-like proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.27.16782

The multidomain protein Trio binds the LAR transmembrane tyrosine phosphatase, contains a protein kinase domain, and has separate rac-specific and rho-specific guanine nucleotide exchange factor domains

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.27.16782

The Caenorhabditis elegans gene unc-89, required fpr muscle M-line assembly, encodes a giant modular protein composed of Ig and signal transduction domains

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.27.16782

Interaction of the Nck adapter protein with p21-activated kinase (PAK1)

21 January 2018

1 reference

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Isolation and characterization of the faciogenital dysplasia (Aarskog-Scott syndrome) gene: a putative Rho/Rac guanine nucleotide exchange factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.27.16782

Faciogenital dysplasia protein (FGD1) and Vav, two related proteins required for normal embryonic development, are upstream regulators of Rho GTPases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.27.16782

The faciogenital dysplasia gene product FGD1 functions as a Cdc42Hs-specific guanine-nucleotide exchange factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.27.16782

A role for Rac in Tiam1-induced membrane ruffling and invasion

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.27.16782

Catalysis of guanine nucleotide exchange on the CDC42Hs protein by the dbl oncogene product

21 January 2018

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The predicted DBL oncogene product defines a distinct class of transforming proteins

21 January 2018

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JNK1: a protein kinase stimulated by UV light and Ha-Ras that binds and phosphorylates the c-Jun activation domain

21 January 2018

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Subcellular localization and quantitation of the major neutrophil pertussis toxin substrate, Gn

21 January 2018

1 reference

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Activation of mitogen-activated protein kinase cascades by p21-activated protein kinases in cell-free extracts of Xenopus oocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.27.16782

Cdc42 and PAK-mediated signaling leads to Jun kinase and p38 mitogen-activated protein kinase activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.27.16782

Human p21-activated kinase (Pak1) regulates actin organization in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.27.16782

Human Ste20 homologue hPAK1 links GTPases to the JNK MAP kinase pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.27.16782

Rho Family GTPases Bind to Phosphoinositide Kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.27.16782

PDGF stimulates an increase in GTP-Rac via activation of phosphoinositide 3-kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.27.16782

Phosphatidylinositol 3-kinase signals activate a selective subset of Rac/Rho-dependent effector pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.27.16782

The pleckstrin homology domain mediates transformation by oncogenic dbl through specific intracellular targeting

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.27.16782

Expression Cloning of lfc, a Novel Oncogene with Structural Similarities to Guanine Nucleotide Exchange Factors and to the Regulatory Region of Protein Kinase C

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.27.16782

Regulated membrane localization of Tiam1, mediated by the NH2-terminal pleckstrin homology domain, is required for Rac-dependent membrane ruffling and C-Jun NH2-terminal kinase activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.27.16782

Pleckstrin homology domains bind to phosphatidylinositol-4,5-bisphosphate.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.27.16782

Membrane localization of phosphatidylinositol 3-kinase is sufficient to activate multiple signal-transducing kinase pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.27.16782

Lfc and Lsc oncoproteins represent two new guanine nucleotide exchange factors for the Rho GTP-binding protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.27.16782

Oncogene ect2 is related to regulators of small GTP-binding proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.27.16782

Rac and Cdc42 induce actin polymerization and G1 cell cycle progression independently of p65PAK and the JNK/SAPK MAP kinase cascade

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.27.16782

RAC regulation of actin polymerization and proliferation by a pathway distinct from Jun kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.27.16782

Guanine nucleotide binding properties of Rac2 mutant proteins and analysis of the responsiveness to guanine nucleotide dissociation stimulator

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.27.16782

PAK kinases are directly coupled to the PIX family of nucleotide exchange factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.27.16782

21 January 2018

Identifiers

DOI

10.1074/JBC.273.27.16782

1 reference

2 August 2017

1 reference