(Q34465498)

2 August 2017

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title

Molecular mechanisms for protein kinase A-mediated modulation of immune function (English)

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2 August 2017

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Kjetil Taskén

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Sheraz Yaqub

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2 August 2017

author name string

Knut Martin Torgersen

series ordinal

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2 August 2017

Torkel Vang

series ordinal

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2 August 2017

Hilde Abrahamsen

series ordinal

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2 August 2017

publication date

1 January 2002

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2 August 2017

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inferred from page(s)

published in

Cellular Signalling

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2 August 2017

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2 August 2017

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2 August 2017

page(s)

1-9

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Adapter proteins in lymphocyte antigen-receptor signaling

2 August 2017

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Epac is a Rap1 guanine-nucleotide-exchange factor directly activated by cyclic AMP

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7 January 2021

Protein kinase A anchoring

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7 January 2021

CD3- and CD28-dependent induction of PDE7 required for T cell activation

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7 January 2021

Association with the SRC family tyrosyl kinase LYN triggers a conformational change in the catalytic region of human cAMP-specific phosphodiesterase HSPDE4A4B. Consequences for rolipram inhibition

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7 January 2021

Infection of CD4+ memory T cells by HIV-1 requires expression of phosphodiesterase 4.

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7 January 2021

Regulation of cAMP and cGMP signaling: new phosphodiesterases and new functions

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7 January 2021

Adaptation in cyclic AMP signalling processes: A central role for cyclic AMP phosphodiesterases

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7 January 2021

CD3-dependent increase in cyclic AMP in human T-cells following stimulation of the CD2 receptor

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7 January 2021

Stimulation of T-cells with OKT3 antibodies increases forskolin binding and cyclic AMP accumulation

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7 January 2021

The adenylate cyclase-cAMP-protein kinase A pathway and regulation of the immune response

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Protein kinase A type I antagonist restores immune responses of T cells from HIV-infected patients.

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7 January 2021

High prevalence of T cell type I protein kinase A deficiency in systemic lupus erythematosus

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7 January 2021

Interleukin 2 transcription factors as molecular targets of cAMP inhibition: delayed inhibition kinetics and combinatorial transcription roles

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7 January 2021

Signal transduction by the TCR for antigen

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7 January 2021

Regulation of antigen receptor signal transduction by protein tyrosine kinases

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7 January 2021

Molecular basis for interaction of the protein tyrosine kinase ZAP-70 with the T-cell receptor

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7 January 2021

Aggregation of lipid rafts accompanies signaling via the T cell antigen receptor

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7 January 2021

LAT: the ZAP-70 tyrosine kinase substrate that links T cell receptor to cellular activation

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7 January 2021

Molecular cloning of the cDNA encoding pp36, a tyrosine-phosphorylated adaptor protein selectively expressed by T cells and natural killer cells

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7 January 2021

T cell antigen-receptor signal transduction

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7 January 2021

Association of Grb2, Gads, and phospholipase C-gamma 1 with phosphorylated LAT tyrosine residues. Effect of LAT tyrosine mutations on T cell angigen receptor-mediated signaling

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7 January 2021

The human p50csk tyrosine kinase phosphorylates p56lck at Tyr-505 and down regulates its catalytic activity

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7 January 2021

Negative regulation of T-cell receptor signalling by tyrosine protein kinase p50csk

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7 January 2021

Functions of lipid rafts in biological membranes

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7 January 2021

Lipid rafts and signal transduction

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7 January 2021

S-acylation of LCK protein tyrosine kinase is essential for its signalling function in T lymphocytes

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7 January 2021

Csk suppression of Src involves movement of Csk to sites of Src activity

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7 January 2021

Requirement of the SH3 and SH2 domains for the inhibitory function of tyrosine protein kinase p50csk in T lymphocytes.

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7 January 2021

Transmembrane phosphoprotein Cbp regulates the activities of Src-family tyrosine kinases

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7 January 2021

Phosphoprotein associated with glycosphingolipid-enriched microdomains (PAG), a novel ubiquitously expressed transmembrane adaptor protein, binds the protein tyrosine kinase csk and is involved in regulation of T cell activation

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7 January 2021

Transcriptional regulation of T lymphocyte development and function

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7 January 2021

Protein-kinase-A-dependent activator in transcription factor CREB reveals new role for CREM repressors

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7 January 2021

Phosphorylated CREB binds specifically to the nuclear protein CBP

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7 January 2021

Nuclear protein CBP is a coactivator for the transcription factor CREB

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7 January 2021

Transcription from a murine T-cell receptor V beta promoter depends on a conserved decamer motif similar to the cyclic AMP response element

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7 January 2021

Defective thymocyte proliferation and IL-2 production in transgenic mice expressing a dominant-negative form of CREB

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7 January 2021

A protein kinase C-, Ras-, and RSK2-dependent signal transduction pathway activates the cAMP-responsive element-binding protein transcription factor following T cell receptor engagement

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7 January 2021

Cyclic AMP stimulates somatostatin gene transcription by phosphorylation of CREB at serine 133

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7 January 2021

Transcription factors of the NFAT family: regulation and function

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7 January 2021

Integration of calcium and cyclic AMP signaling pathways by 14-3-3

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7 January 2021

Direct interaction between protein kinase C theta (PKC theta) and 14-3-3 tau in T cells: 14-3-3 overexpression results in inhibition of PKC theta translocation and function

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7 January 2021

NF-kappa B and related proteins: Rel/dorsal homologies meet ankyrin-like repeats

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7 January 2021

Rel/NF-kappa B/I kappa B family: intimate tales of association and dissociation

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7 January 2021

PKC-θ is required for TCR-induced NF-κB activation in mature but not immature T lymphocytes

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7 January 2021

The transcriptional activity of NF-kappaB is regulated by the IkappaB-associated PKAc subunit through a cyclic AMP-independent mechanism

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7 January 2021

Historical perspectives and new insights involving the MAP kinase cascades.

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7 January 2021

Mechanism of inhibition of Raf-1 by protein kinase A.

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7 January 2021

Inhibition of the EGF-Activated MAP Kinase Signaling Pathway by Adenosine 3′,5′-Monophosphate

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7 January 2021

Phosphorylation of serine 43 is not required for inhibition of c-Raf kinase by the cAMP-dependent protein kinase.

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7 January 2021

Negative regulation of Raf-1 by phosphorylation of serine 621.

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7 January 2021

Cell type-specific regulation of B-Raf kinase by cAMP and 14-3-3 proteins

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7 January 2021

14-3-3 proteins are required for maintenance of Raf-1 phosphorylation and kinase activity

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7 January 2021

cAMP activates MAP kinase and Elk-1 through a B-Raf- and Rap1-dependent pathway

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7 January 2021

Crosstalk between cAMP-dependent kinase and MAP kinase through a protein tyrosine phosphatase

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7 January 2021

A novel regulatory mechanism of MAP kinases activation and nuclear translocation mediated by PKA and the PTP-SL tyrosine phosphatase

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7 January 2021

The Ets-1 transcription factor is required for the development of natural killer cells in mice

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7 January 2021

Increased intracellular cyclic AMP inhibits inositol phospholipid hydrolysis induced by perturbation of the T cell receptor/CD3 complex but not by G-protein stimulation. Association with protein kinase A-mediated phosphorylation of phospholipase C-g

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7 January 2021

Regulation by cAMP-dependent protein kinease of a G-protein-mediated phospholipase C.

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7 January 2021

Phosphorylation of serine 1105 by protein kinase A inhibits phospholipase Cbeta3 stimulation by Galphaq

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7 January 2021

T cell activation and the cytoskeleton

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7 January 2021

The immunological synapse and the actin cytoskeleton: molecular hardware for T cell signaling.

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7 January 2021

Regulation of the cytoskeleton and cell adhesion by the Rho family GTPases in mammalian cells.

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7 January 2021

Rho- and rac-dependent assembly of focal adhesion complexes and actin filaments in permeabilized fibroblasts: an essential role for ezrin/radixin/moesin proteins

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7 January 2021

Elevation of intracellular cAMP inhibits RhoA activation and integrin-dependent leukocyte adhesion induced by chemoattractants.

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7 January 2021

cAMP-induced morphological changes are counteracted by the activated RhoA small GTPase and the Rho kinase ROKalpha

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7 January 2021

Ezrin is a cyclic AMP-dependent protein kinase anchoring protein

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7 January 2021

Location of cAMP-dependent protein kinase type I with the TCR-CD3 complex

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7 January 2021

Cyclic AMP-dependent protein kinase (cAK) in human B cells: co-localization of type I cAK (RI alpha 2 C2) with the antigen receptor during anti-immunoglobulin-induced B cell activation

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7 January 2021

Selective Activation of cAMP-dependent Protein Kinase Type I Inhibits Rat Natural Killer Cell Cytotoxicity

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7 January 2021

Activation of the COOH-terminal Src kinase (Csk) by cAMP-dependent protein kinase inhibits signaling through the T cell receptor

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7 January 2021

Thy-1 glycoprotein and src-like protein-tyrosine kinase p53/p56lyn are associated in large detergent-resistant complexes in rat basophilic leukemia cells

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7 January 2021

The association of the protein tyrosine kinases p56lck and p60fyn with the glycosyl phosphatidylinositol-anchored proteins Thy-1 and CD48 in rat thymocytes is dependent on the state of cellular activation

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7 January 2021

Molecular alterations of the Fyn-complex occur as late events of human T cell activation

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7 January 2021

Release from tonic inhibition of T cell activation through transient displacement of C-terminal Src kinase (Csk) from lipid rafts

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7 January 2021

Sequence requirements for association of protein-tyrosine phosphatase PEP with the Src homology 3 domain of inhibitory tyrosine protein kinase p50(csk)

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7 January 2021

SH2 domain-mediated interaction of inhibitory protein tyrosine kinase Csk with protein tyrosine phosphatase-HSCF

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7 January 2021

Cooperative inhibition of T-cell antigen receptor signaling by a complex between a kinase and a phosphatase

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7 January 2021

LAT is required for TCR-mediated activation of PLCgamma1 and the Ras pathway

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7 January 2021

Functional analysis of LAT in TCR-mediated signaling pathways using a LAT-deficient Jurkat cell line

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7 January 2021

Essential role of LAT in T cell development

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7 January 2021

Dok-3, a novel adapter molecule involved in the negative regulation of immunoreceptor signaling

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7 January 2021

Regulation of cAMP-mediated signal transduction via interaction of caveolins with the catalytic subunit of protein kinase A

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7 January 2021

Organization of G proteins and adenylyl cyclase at the plasma membrane

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7 January 2021

Transmembrane Phosphoprotein Cbp Positively Regulates the Activity of the Carboxyl-terminal Src Kinase, Csk

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7 January 2021

HIV-1 protease inhibitors

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7 January 2021

A controlled trial of two nucleoside analogues plus indinavir in persons with human immunodeficiency virus infection and CD4 cell counts of 200 per cubic millimeter or less. AIDS Clinical Trials Group 320 Study Team

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7 January 2021

HIV treatment strategies: planning for the long term

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7 January 2021

Presence of an inducible HIV-1 latent reservoir during highly active antiretroviral therapy

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7 January 2021

Latent infection of CD4+ T cells provides a mechanism for lifelong persistence of HIV-1, even in patients on effective combination therapy

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7 January 2021

Latent reservoirs of HIV: obstacles to the eradication of virus

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7 January 2021

Immunosuppressive retroviral peptides: cAMP and cytokine patterns

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7 January 2021

Human immunodeficiency virus proteins induce the inhibitory cAMP/protein kinase A pathway in normal lymphocytes

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7 January 2021

Human immunodeficiency virus replication: modulation by cellular levels of cAMP

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7 January 2021

Restoration of T-cell function in HIV infection by reduction of intracellular cAMP levels with adenosine analogues

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7 January 2021

10.1016/S0898-6568(01)00214-5

Identifiers

DOI

1 reference

2 August 2017

1 reference