(Q34452585)

2 August 2017

title

Prostaglandin E2 activates and utilizes mTORC2 as a central signaling locus for the regulation of mast cell chemotaxis and mediator release (English)

1 reference

2 August 2017

0 references

1 reference

1 reference

Dean D Metcalfe

1 reference

2 August 2017

Alasdair M Gilfillan

1 reference

2 August 2017

Michael A Beaven

1 reference

2 August 2017

Hye Sun Kuehn

1 reference

2 August 2017

Mi-Yeon Jung

1 reference

2 August 2017

language of work or name

English

0 references

publication date

27 October 2010

1 reference

full work available at URL

2 August 2017

http://www.jbc.org/content/286/1/391.full.pdf

file format

Portable Document Format

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20980255

http://intl.jbc.org/cgi/content/abstract/286/1/391

11 August 2024

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20980255

https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20980255/pdf/?tool=EBI

11 August 2024

file format

Portable Document Format

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20980255

https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20980255/?tool=EBI

11 August 2024

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20980255

https://europepmc.org/articles/PMC3012997

11 August 2024

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20980255

https://europepmc.org/articles/PMC3012997?pdf=render

11 August 2024

file format

Portable Document Format

content deliverer

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20980255

https://doi.org/10.1074/jbc.m110.164772

11 August 2024

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20980255

Journal of Biological Chemistry

11 August 2024

published in

1 reference

2 August 2017

volume

286

1 reference

2 August 2017

1 reference

2 August 2017

page(s)

391-402

1 reference

Btk-dependent Rac activation and actin rearrangement following FcepsilonRI aggregation promotes enhanced chemotactic responses of mast cells

2 August 2017

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The phosphoinositide 3-kinase-dependent activation of Btk is required for optimal eicosanoid production and generation of reactive oxygen species in antigen-stimulated mast cells

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Essential role of EP3 subtype in prostaglandin E2-induced adhesion of mouse cultured and peritoneal mast cells to the Arg-Gly-Asp-enriched matrix.

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Activation and function of the mTORC1 pathway in mast cells

6 July 2018

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Isoform-specific functions of phosphoinositide 3-kinases: p110 delta but not p110 gamma promotes optimal allergic responses in vivo

6 July 2018

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Synergistic activation of phospholipases Cgamma and Cbeta: a novel mechanism for PI3K-independent enhancement of FcepsilonRI-induced mast cell mediator release

6 July 2018

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G protein-coupled receptors and the modification of FcepsilonRI-mediated mast cell activation

6 July 2018

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Chemotactic action of prostaglandin E2 on mouse mast cells acting via the PGE2 receptor 3.

6 July 2018

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Involvement of Fyn kinase in Kit and integrin-mediated Rac activation, cytoskeletal reorganization, and chemotaxis of mast cells.

6 July 2018

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Antigen receptor signalling: a distinctive role for the p110delta isoform of PI3K.

6 July 2018

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Reactive oxygen and nitrogen species as signaling molecules regulating neutrophil function

6 July 2018

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When translation meets transformation: the mTOR story

6 July 2018

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Stress and mTORture signaling

6 July 2018

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Development, migration, and survival of mast cells

6 July 2018

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Integrated signalling pathways for mast-cell activation

6 July 2018

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TOR signaling in growth and metabolism

6 July 2018

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Prostaglandin E2 activates EP2 receptors to inhibit human lung mast cell degranulation

6 July 2018

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Evaluation of selective prostaglandin E2 (PGE2) receptor agonists as therapeutic agents for the treatment of asthma

6 July 2018

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Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex

6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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Prostaglandin E2 selectively enhances the IgE-mediated production of IL-6 and granulocyte-macrophage colony-stimulating factor by mast cells through an EP1/EP3-dependent mechanism.

6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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Activation of the mitogen-activated protein kinase/cytosolic phospholipase A2 pathway in a rat mast cell line. Indications of different pathways for release of arachidonic acid and secretory granules

6 July 2018

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6 July 2018

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Antibodies to IL-3 and IL-4 suppress helminth-induced intestinal mastocytosis

6 July 2018

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6 July 2018

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Inflammation in amyotrophic lateral sclerosis spinal cord and brain is mediated by activated macrophages, mast cells and T cells

6 July 2018

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Effect of endogenous and exogenous prostaglandin E(2) on interleukin-1 beta-induced cyclooxygenase-2 expression in human airway smooth-muscle cells

21 January 2018

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FcepsilonRI- and Fcgamma receptor-mediated production of reactive oxygen species by mast cells is lipoxygenase- and cyclooxygenase-dependent and NADPH oxidase-independent

21 January 2018

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Determination of protein phosphorylation in Fc epsilon RI-activated human mast cells by immunoblot analysis requires protein extraction under denaturing conditions

21 January 2018

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Receptors and signaling mechanisms required for prostaglandin E2-mediated regulation of mast cell degranulation and IL-6 production

21 January 2018

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Prostaglandin E2 promotes degranulation-independent release of MCP-1 from mast cells

21 January 2018

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Human mast cells express multiple EP receptors for prostaglandin E2 that differentially modulate activation responses

21 January 2018

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Differential involvement of NF-kappaB and MAP kinase pathways in the generation of inflammatory cytokines by human neutrophils.

21 January 2018

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Growth of human mast cells from bone marrow and peripheral blood-derived CD34+ pluripotent progenitor cells

21 January 2018

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Novel role of transmembrane SCF for mast cell activation and eotaxin production in mast cell-fibroblast interactions.

27 October 2018

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Critical protective role of mast cells in a model of acute septic peritonitis

27 October 2018

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Macrophages synthesise and release prostaglandins in response to inflammatory stimuli

21 January 2018

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The c-kit receptor ligand functions as a mast cell chemoattractant

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20980255

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1074/JBC.M110.164772

1 reference

2 August 2017

1 reference

2 August 2017

1 reference