(Q34448258)

2 August 2017

title

Quinidine and the identification of drugs whose elimination is impaired in subjects classified as poor metabolizers of debrisoquine (English)

1 reference

2 August 2017

Speirs CJ

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2 August 2017

Murray S

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2 August 2017

Boobis AR

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2 August 2017

Seddon CE

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2 August 2017

Davies DS

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2 August 2017

language of work or name

English

0 references

publication date

1 December 1986

1 reference

British Journal of Clinical Pharmacology

2 August 2017

published in

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2 August 2017

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2 August 2017

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2 August 2017

page(s)

739-743

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A family and population study of the genetic polymorphism of debrisoquine oxidation in a white British population.

2 August 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1401220

Accumulation of debrisoquine by platelets in vivo: a model of events at the peripheral adrenergic neurone

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1401220

Evidence for an enzymatic defect in the 4-hydroxylation of debrisoquine by human liver

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1401220

Impaired oxidation of debrisoquine in patients with perhexiline neuropathy

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1401220

Substrate specificity of the form of cytochrome P-450 catalyzing the 4-hydroxylation of debrisoquine in man

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1401220

Quinidine-induced rise in ajmaline plasma concentration

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1401220

Phenacetin O-deethylase: an activity of a cytochrome P-450 showing genetic linkage with that catalysing the 4-hydroxylation of debrisoquine?

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1401220

Polymorphic metabolism of mephenytoin in man: pharmacokinetic interaction with a co-regulated substrate, mephobarbital

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1401220

The disposition of debrisoquine in hypertensive patients

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1401220

Polymorphic hydroxylation of Debrisoquine in man.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1401220

Competitive inhibition of sparteine oxidation in human liver by β-adrenoceptor antagonists and other cardiovascular drugs

6 July 2018

1 reference

Crossref

https://api.crossref.org/works/10.1111%2FJ.1365-2125.1986.TB02969.X

Lack of congruence ofS-carboxymethyl-L-cysteine sulphoxidation and debrisoquine 4-hydroxylation in a Caucasian population

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1111%2FJ.1365-2125.1986.TB02969.X

Impairment of phenytoin parahydroxylation as a cause of severe intoxication

21 January 2018

1 reference

12 December 2020

Genetic polymorphism in drug oxidation: in vitro studies of human debrisoquine 4-hydroxylase and bufuralol 1'-hydroxylase activities

1 reference

12 December 2020

In vitro inhibition studies of two isozymes of human liver cytochrome P-450. Mephenytoin p-hydroxylase and sparteine monooxygenase

1 reference

12 December 2020

An assay for paracetamol, produced by the O-deethylation of phenacetin in vitro, using gas chromatography/electron capture negative ion chemical ionization mass spectrometry

1 reference

12 December 2020

Single-dose quinidine treatment inhibits metoprolol oxidation in extensive metabolizers

1 reference

12 December 2020

Quinidine pharmacokinetics in man: choice of a disposition model and absolute bioavailability studies

1 reference

12 December 2020

Influence of DH/DL alleles regulating debrisoquine oxidation on phenytoin hydroxylation

1 reference

12 December 2020

Genetically determined impaired drug sulphoxidation

1 reference

12 December 2020

10.1111/J.1365-2125.1986.TB02969.X

Identifiers

DOI

1 reference

2 August 2017

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2 August 2017

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