(Q34388612)

1 August 2017

title

Genome scan for human obesity and linkage to markers in 20q13. (English)

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1 August 2017

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ORCID Public Data File 2021

1 August 2017

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author name string

J H Lee

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1 August 2017

W D Li

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1 August 2017

W Xu

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1 August 2017

E J Joo

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1 August 2017

R L Kilker

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1 August 2017

E Nanthakumar

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1 August 2017

M North

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1 August 2017

H Sakul

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1 August 2017

C Bell

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1 August 2017

R A Price

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1 August 2017

language of work or name

English

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publication date

1 January 1999

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American Journal of Human Genetics

1 August 2017

published in

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1 August 2017

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1 August 2017

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1 August 2017

page(s)

196-209

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Dieting, exercise, or disordered eating does not account for extremes of body weight within families

1 August 2017

cites work

1 reference

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6 July 2018

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6 July 2018

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A mutation in the human leptin receptor gene causes obesity and pituitary dysfunction

6 July 2018

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6 July 2018

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CAT scans, PET scans, and genomic scans

6 July 2018

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Prader-Willi and other syndromes associated with obesity and mental retardation

6 July 2018

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6 July 2018

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Meta-analysis of linkage data under worst-case conditions: a demonstration using the human OB region

6 July 2018

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Autosomal genomic scan for loci linked to obesity and energy metabolism in Pima Indians

6 July 2018

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Comparison of nonparametric statistics for detection of linkage in nuclear families: single-marker evaluation

6 July 2018

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Recessive inheritance of obesity in familial non-insulin-dependent diabetes mellitus, and lack of linkage to nine candidate genes

6 July 2018

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ART (protein product of agouti-related transcript) as an antagonist of MC-3 and MC-4 receptors

6 July 2018

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Identification of an obesity quantitative trait locus on mouse chromosome 2 and evidence of linkage to body fat and insulin on the human homologous region 20q.

6 July 2018

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Obesity and impaired prohormone processing associated with mutations in the human prohormone convertase 1 gene

6 July 2018

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A new class of obesity genes encodes leukocyte adhesion receptors

6 July 2018

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Congenital leptin deficiency is associated with severe early-onset obesity in humans

6 July 2018

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Markers for the gene ob and serum leptin levels in human morbid obesity

6 July 2018

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Linkage of genetic markers on human chromosomes 20 and 12 to NIDDM in Caucasian sib pairs with a history of diabetic nephropathy

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1377718

Genetic variants of the human obesity (OB) gene: association with body mass index in young women, psychiatric symptoms, and interaction with the dopamine D2 receptor (DRD2) gene

6 July 2018

1 reference

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A major quantitative trait locus determining serum leptin levels and fat mass is located on human chromosome 2

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1377718

Targeted disruption of the melanocortin-4 receptor results in obesity in mice

6 July 2018

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Genomewide search for genes influencing percent body fat in Pima Indians: suggestive linkage at chromosome 11q21-q22. Pima Diabetes Gene Group

6 July 2018

1 reference

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A metric map of humans: 23,500 loci in 850 bands

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1377718

Mutations in the hepatocyte nuclear factor-4alpha gene in maturity-onset diabetes of the young (MODY1)

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1377718

A novel microsatellite polymorphism in the human OB gene: a highly polymorphic marker for linkage analysis

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1377718

OB gene not linked to human obesity in Mexican American affected sib pairs from Starr County, Texas

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1377718

Absence of linkage of obesity and energy metabolism to markers flanking homologues of rodent obesity genes in Pima Indians

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1377718

Quantitative variation in obesity-related traits and insulin precursors linked to the OB gene region on human chromosome 7.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1377718

Parametric and nonparametric linkage analysis: a unified multipoint approach

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1377718

Extreme obesity may be linked to markers flanking the human OB gene

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1377718

Indication for linkage of the human OB gene region with extreme obesity

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1377718

A comprehensive genetic map of the human genome based on 5,264 microsatellites

6 July 2018

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A collection of tri- and tetranucleotide repeat markers used to generate high quality, high resolution human genome-wide linkage maps

6 July 2018

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Major gene with sex-specific effects influences fat mass in Mexican Americans.

6 July 2018

1 reference

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Cloning of the mouse agouti gene predicts a secreted protein ubiquitously expressed in mice carrying the lethal yellow mutation

6 July 2018

1 reference

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Faster sequential genetic linkage computations

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1377718

Automated construction of genetic linkage maps using an expert system (MultiMap): a human genome linkage map.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1377718

Agouti protein is an antagonist of the melanocyte-stimulating-hormone receptor

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1377718

Dietary obesity linked to genetic loci on chromosomes 9 and 15 in a polygenic mouse model

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1377718

Eating disorder and epilepsy in mice lacking 5-HT2c serotonin receptors

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1377718

Complete multipoint sib-pair analysis of qualitative and quantitative traits

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1377718

Identification of microsatellite markers near the human ob gene and linkage studies in NIDDM-affected sib pairs

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1377718

Genetic dissection of complex traits: guidelines for interpreting and reporting linkage results

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1377718

Cascade regulation of terminal adipocyte differentiation by three members of the C/EBP family of leucine zipper proteins

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1377718

Strategies for multilocus linkage analysis in humans

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1377718

Easy calculations of lod scores and genetic risks on small computers

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1377718

A comparison of sib-pair linkage tests for disease susceptibility loci

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1377718

Genetic contributions to human fatness: an adoption study.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1377718

Genetics of obesity in adult adoptees and their biological siblings

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1377718

Common major gene inheritance of extreme overweight.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1377718

Measuring the inflation of the lod score due to its maximization over model parameter values in human linkage analysis

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1377718

A note on multiple testing procedures in linkage analysis

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1377718

Use of the robust sib-pair method to screen for single-locus, multiple-locus, and pleiotropic effects: application to traits related to hypertension

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1377718

The genetic and environmental sources of body mass index variability: the Muscatine Ponderosity Family Study

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1377718

Strategies for characterizing highly polymorphic markers in human gene mapping

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1377718

Molecular characterization of the mouse agouti locus.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1377718

An exploratory investigation of genetic linkage with body composition and fatness phenotypes: the Québec Family Study

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1377718

A leptin missense mutation associated with hypogonadism and morbid obesity.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1377718

Significance levels in complex inheritance

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1377718

False discoveries in genome scanning

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1377718

Peroxisome proliferator activated receptor gamma, CCAAT/enhancer-binding protein alpha, and cell cycle status regulate the commitment to adipocyte differentiation

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1377718

Hypogonadism and obesity in mice with a targeted deletion of the Nhlh2 gene

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1377718

Detection of obesity QTLs on mouse chromosomes 1 and 7 by selective DNA pooling.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1377718

Statistical validity of the Haseman-Elston sib-pair test in small samples.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1377718

Avoiding recomputation in linkage analysis.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1377718

The Body-Mass Index of Twins Who Have Been Reared Apart

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1377718

Body fat in identical twins reared apart: roles for genes and environment

9 December 2018

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12 December 2020

The investigation of linkage between a quantitative trait and a marker locus

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12 December 2020

A comparison of three affected-sib-pair scoring methods to detect HLA-linked disease susceptibility genes

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12 December 2020

Definition, measurement, and classification of the syndromes of obesity

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12 December 2020

Lipoprotein lipase gene polymorphisms: associations with hypertriglyceridemia and body mass index in obese people

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12 December 2020

Genetic mapping of quantitative trait loci for growth and fatness in pigs

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12 December 2020

Linkage analysis in nuclear families. 2: Relationship between affected sib-pair tests and lod score analysis

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12 December 2020

Human obesity does not segregate with the chromosomal regions of Prader-Willi, Bardet-Biedl, Cohen, Borjeson or Wilson-Turner syndromes

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12 December 2020

Development of obesity following inactivation of a growth hormone transgene in mice

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12 December 2020

Genetic dissection of complex traits

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12 December 2020

Genetic dissection of complex traits

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12 December 2020

Absence of linkage between human obesity and the mouse agouti homologous region (20q11.2) or other markers spanning chromosome 20q

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12 December 2020

A putative vulnerability locus to multiple sclerosis maps to 5p14-p12 in a region syntenic to the murine locus Eae2

1 reference

12 December 2020

Sensitivity to dietary obesity linked to a locus on chromosome 15 in a CAST/Ei x C57BL/6J F2 intercross

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12 December 2020

New susceptibility locus for NIDDM is localized to human chromosome 20q

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12 December 2020

Novel polymorphism of the human ob gene promoter in lean and morbidly obese subjects

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12 December 2020

A susceptibility locus for early-onset non-insulin dependent (type 2) diabetes mellitus maps to chromosome 20q, proximal to the phosphoenolpyruvate carboxykinase gene

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12 December 2020

Relationship of a novel polymorphic marker near the human obese (OB) gene to fat mass in healthy women

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12 December 2020

Familial lipoprotein lipase (LPL) deficiency: A catalogue of LPL gene mutations identified in 20 patients from the UK, Sweden, and Italy

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12 December 2020

Further support for linkage of extreme obesity to the obese gene in a study group of obese children and adolescents

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12 December 2020

A genetic polymorphism of the peroxisome proliferator-activated receptor gamma gene influences plasma leptin levels in obese humans

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12 December 2020

Overweight and obesity in the United States: prevalence and trends, 1960-1994

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12 December 2020

Localization of the gene for familial partial lipodystrophy (Dunnigan variety) to chromosome 1q21–22

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12 December 2020

Novel polymorphisms in the 5' region of the LEP gene: association with leptin levels and response to low-calorie diet in human obesity

1 reference

12 December 2020

A polymorphism in the 5' untranslated region of the human ob gene is associated with low leptin levels

1 reference

12 December 2020

1 reference

12 December 2020

Identifiers

DOI

10.1086/302195

1 reference

1 August 2017

1 reference

1 August 2017

1 reference