(Q34332162)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15141093%20AND%20SRC:MED&resulttype=core&format=json

28 December 2019

title

Leptin modulates beta cell expression of IL-1 receptor antagonist and release of IL-1beta in human islets (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15141093%20AND%20SRC:MED&resulttype=core&format=json

28 December 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15141093%20AND%20SRC:MED&resulttype=core&format=json

28 December 2019

Kathrin Maedler

0 references

Domenico Bosco

0 references

Pavel Sergeev

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15141093%20AND%20SRC:MED&resulttype=core&format=json

28 December 2019

Zoltan Mathe

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15141093%20AND%20SRC:MED&resulttype=core&format=json

28 December 2019

Thierry Berney

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15141093%20AND%20SRC:MED&resulttype=core&format=json

28 December 2019

Jean-Michel Dayer

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15141093%20AND%20SRC:MED&resulttype=core&format=json

28 December 2019

Manfred Reinecke

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15141093%20AND%20SRC:MED&resulttype=core&format=json

28 December 2019

Philippe A Halban

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15141093%20AND%20SRC:MED&resulttype=core&format=json

28 December 2019

Marc Y Donath

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15141093%20AND%20SRC:MED&resulttype=core&format=json

28 December 2019

language of work or name

English

0 references

publication date

12 May 2004

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15141093%20AND%20SRC:MED&resulttype=core&format=json

28 December 2019

number of pages

1 reference

Proceedings of the National Academy of Sciences of the United States of America

inferred from page(s)

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15141093%20AND%20SRC:MED&resulttype=core&format=json

28 December 2019

volume

101

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15141093%20AND%20SRC:MED&resulttype=core&format=json

28 December 2019

issue

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15141093%20AND%20SRC:MED&resulttype=core&format=json

28 December 2019

page(s)

8138-8143

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15141093%20AND%20SRC:MED&resulttype=core&format=json

Inflammatory mediators and islet beta-cell failure: a link between type 1 and type 2 diabetes

28 December 2019

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=419570

Inflammatory cytokines and the risk to develop type 2 diabetes: results of the prospective population-based European Prospective Investigation into Cancer and Nutrition (EPIC)-Potsdam Study

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=419570

Beta-cell deficit and increased beta-cell apoptosis in humans with type 2 diabetes

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=419570

Beta-cell dysfunction and insulin resistance in type 2 diabetes: role of metabolic and genetic abnormalities

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=419570

Glucose-induced beta cell production of IL-1beta contributes to glucotoxicity in human pancreatic islets

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=419570

Glucose-dependent insulinotropic polypeptide activates the Raf-Mek1/2-ERK1/2 module via a cyclic AMP/cAMP-dependent protein kinase/Rap1-mediated pathway.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=419570

FLIP switches Fas-mediated glucose signaling in human pancreatic beta cells from apoptosis to cell replication

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=419570

Identification of leptin receptors in human breast cancer: functional activity in the T47-D breast cancer cell line

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=419570

Leptin increases the viability of isolated rat pancreatic islets by suppressing apoptosis

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=419570

High glucose causes apoptosis in cultured human pancreatic islets of Langerhans: a potential role for regulation of specific Bcl family genes toward an apoptotic cell death program

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=419570

Leptin directly induces the secretion of interleukin 1 receptor antagonist in human monocytes

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=419570

Biological role of interleukin 1 receptor antagonist isoforms

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=419570

The role of the interleukin-1-receptor antagonist in blocking inflammation mediated by interleukin-1.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=419570

Importance of cell-matrix interactions in rat islet beta-cell secretion in vitro: role of alpha6beta1 integrin

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=419570

Islet growth and development in the adult

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=419570

Hyperglycemia-induced beta-cell apoptosis in pancreatic islets of Psammomys obesus during development of diabetes.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=419570

Fatty acids, lipotoxicity and insulin secretion

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=419570

Leptin suppression of insulin secretion and gene expression in human pancreatic islets: implications for the development of adipogenic diabetes mellitus

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=419570

Glucose and tolbutamide induce apoptosis in pancreatic beta-cells. A process dependent on intracellular Ca2+ concentration

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=419570

Protection against lipoapoptosis of beta cells through leptin-dependent maintenance of Bcl-2 expression

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=419570

Leptin induces proliferation of pancreatic beta cell line MIN6 through activation of mitogen-activated protein kinase

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=419570

Leptin rapidly suppresses insulin release from insulinoma cells, rat and human islets and, in vivo, in mice

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=419570

Tissue triglycerides, insulin resistance, and insulin production: implications for hyperinsulinemia of obesity

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=419570

beta-cell function in normal rats made chronically hyperleptinemic by adenovirus-leptin gene therapy

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=419570

Expression of the functional leptin receptor mRNA in pancreatic islets and direct inhibitory action of leptin on insulin secretion

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=419570

Leptin receptors expressed on pancreatic beta-cells

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=419570

Positional cloning of the mouse obese gene and its human homologue

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=419570

Recombinant mouse OB protein: evidence for a peripheral signal linking adiposity and central neural networks

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=419570

Lipotoxicity in the pathogenesis of obesity-dependent NIDDM. Genetic and clinical implications.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=419570

Insulin deficiency and insulin resistance in the pathogenesis of NIDDM: is a divorce possible?

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=419570

Hyperglycaemia as an inducer as well as a consequence of impaired islet cell function and insulin resistance: implications for the management of diabetes.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=419570

A urine inhibitor of interleukin 1 activity affects both interleukin 1 alpha and 1 beta but not tumor necrosis factor alpha.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=419570

A Simple Enzymatic Quantitative Analysis of Triglycerides in Tissues

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=419570

Monounsaturated fatty acids prevent the deleterious effects of palmitate and high glucose on human pancreatic beta-cell turnover and function

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=419570

Glucose induces beta-cell apoptosis via upregulation of the Fas receptor in human islets

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=419570

Distinct effects of saturated and monounsaturated fatty acids on beta-cell turnover and function

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=419570

Pancreatic beta-cell damage mediated by beta-cell production of interleukin-1. A novel mechanism for virus-induced diabetes

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=419570

Divergent roles of SHP-2 in ERK activation by leptin receptors

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=419570

Leptin secretion from subcutaneous and visceral adipose tissue in women

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=419570

The glucose fatty acid cycle in obesity and maturity onset diabetes mellitus

27 October 2018

1 reference

12 December 2020

Fetal pancreatic islets express functional leptin receptors and leptin stimulates proliferation of fetal islet cells

1 reference

12 December 2020

IL-1 receptor antagonist serum levels are increased in human obesity: a possible link to the resistance to leptin?

1 reference

12 December 2020

Interleukin-1 receptor antagonist genotype is associated with coronary atherosclerosis in patients with type 2 diabetes

1 reference

12 December 2020

Growth hormone secretion and leptin in morbid obesity before and after biliopancreatic diversion: relationships with insulin and body composition

1 reference

12 December 2020

Islet Secretion in a New Experimental Model for Non-insulin-dependent Diabetes

1 reference

12 December 2020

Plasma leptin levels and body fat distribution

1 reference

12 December 2020

Inhibition of glucose-induced insulin secretion by long-term preexposure of pancreatic islets to leptin

1 reference

12 December 2020

Sorting human beta-cells consequent to targeted expression of green fluorescent protein

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.0305683101

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15141093%20AND%20SRC:MED&resulttype=core&format=json

28 December 2019

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15141093%20AND%20SRC:MED&resulttype=core&format=json

28 December 2019

PubMed publication ID

15141093

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15141093%20AND%20SRC:MED&resulttype=core&format=json