(Q34306521)

1 August 2017

title

Beta-synuclein regulates Akt activity in neuronal cells. A possible mechanism for neuroprotection in Parkinson's disease (English)

1 reference

1 August 2017

1 reference

1 reference

Edward Rockenstein

1 reference

1 August 2017

Eliezer Masliah

1 reference

1 August 2017

Makoto Hashimoto

1 reference

1 August 2017

Pazit Bar-On

1 reference

1 August 2017

Gilbert Ho

1 reference

1 August 2017

Takato Takenouchi

1 reference

1 August 2017

Leslie Crews

1 reference

1 August 2017

language of work or name

English

0 references

publication date

16 March 2004

1 reference

Journal of Biological Chemistry

1 August 2017

published in

1 reference

1 August 2017

volume

279

1 reference

1 August 2017

1 reference

1 August 2017

page(s)

23622-23629

1 reference

Spectrum of Parkinson's disease, Parkinson's dementia, and Lewy body dementia.

1 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313784200

Alpha-synuclein in Lewy bodies

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313784200

Neurofibrillary tangles in the dentate granule cells of patients with Alzheimer's disease, Lewy body disease and progressive supranuclear palsy

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313784200

Ala30Pro mutation in the gene encoding alpha-synuclein in Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313784200

Mutation in the alpha-synuclein gene identified in families with Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313784200

Dopaminergic loss and inclusion body formation in alpha-synuclein mice: implications for neurodegenerative disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313784200

A Drosophila model of Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313784200

Accelerated in vitro fibril formation by a mutant alpha-synuclein linked to early-onset Parkinson disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313784200

Both familial Parkinson's disease mutations accelerate alpha-synuclein aggregation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313784200

Chronic systemic pesticide exposure reproduces features of Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313784200

Alpha-synuclein up-regulation in substantia nigra dopaminergic neurons following administration of the parkinsonian toxin MPTP.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313784200

Identification of two distinct synucleins from human brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313784200

Peripheral Nervous System-specific Genes Identified by Subtractive cDNA Cloning

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313784200

Synoretin--A new protein belonging to the synuclein family

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313784200

Molecular cloning of cDNA encoding an unrecognized component of amyloid in Alzheimer disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313784200

alpha-Synuclein protects against oxidative stress via inactivation of the c-Jun N-terminal kinase stress-signaling pathway in neuronal cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313784200

Biophysical properties of the synucleins and their propensities to fibrillate: inhibition of alpha-synuclein assembly by beta- and gamma-synucleins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313784200

alpha-Synuclein affects the MAPK pathway and accelerates cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313784200

Alpha-synuclein up-regulates expression of caveolin-1 and down-regulates extracellular signal-regulated kinase activity in B103 neuroblastoma cells: role in the pathogenesis of Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313784200

Role of MAP kinase in neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313784200

Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313784200

Cellular survival: a play in three Akts

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313784200

Reduced neuritic outgrowth and cell adhesion in neuronal cells transfected with human alpha-synuclein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313784200

Fibroblast growth factor 1 regulates signaling via the glycogen synthase kinase-3beta pathway. Implications for neuroprotection

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313784200

The precursor protein of non-A beta component of Alzheimer's disease amyloid is a presynaptic protein of the central nervous system

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313784200

beta-Synuclein inhibits alpha-synuclein aggregation: a possible role as an anti-parkinsonian factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313784200

Beta-synuclein displays an antiapoptotic p53-dependent phenotype and protects neurons from 6-hydroxydopamine-induced caspase 3 activation: cross-talk with alpha-synuclein and implication for Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313784200

The PTEN, Mdm2, p53 tumor suppressor-oncoprotein network

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313784200

6-Hydroxydopamine increases ubiquitin-conjugates and protein degradation: implications for the pathogenesis of Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313784200

Chaperone-like activity of synucleins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313784200

CAIR-1/BAG-3 abrogates heat shock protein-70 chaperone complex-mediated protein degradation: accumulation of poly-ubiquitinated Hsp90 client proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313784200

Modulation of Akt kinase activity by binding to Hsp90

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313784200

Regulation of phospholipase D2: selective inhibition of mammalian phospholipase D isoenzymes by alpha- and beta-synucleins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313784200

alpha-Synuclein interacts with phospholipase D isozymes and inhibits pervanadate-induced phospholipase D activation in human embryonic kidney-293 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313784200

Alpha-synuclein regulates neuronal survival via Bcl-2 family expression and PI3/Akt kinase pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313784200

21 January 2018

Identifiers

DOI

10.1074/JBC.M313784200

1 reference

1 August 2017

1 reference