(Q34286348)

1 August 2017

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title

Asymmetric cell division during animal development (English)

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1 August 2017

main subject

asymmetric cell division

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Knoblich JA

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1 August 2017

publication date

1 January 2001

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Nature Reviews Molecular Cell Biology

1 August 2017

published in

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1 August 2017

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1 August 2017

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1 August 2017

page(s)

11-20

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Mechanisms of asymmetric cell division: Two Bs or not two Bs, that is the question

1 August 2017

cites work

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7 January 2021

The embryonic cell lineage of the nematode Caenorhabditis elegans

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7 January 2021

Molecular genetics of asymmetric cleavage in the early Caenorhabditis elegans embryo

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7 January 2021

PARsing embryonic polarity

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7 January 2021

Early patterning of the C. elegans embryo.

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7 January 2021

MEX-5 and MEX-6 function to establish soma/germline asymmetry in early C. elegans embryos

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7 January 2021

Identification of genes required for cytoplasmic localization in early C. elegans embryos

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7 January 2021

Asymmetrically distributed PAR-3 protein contributes to cell polarity and spindle alignment in early C. elegans embryos

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7 January 2021

par-1, a gene required for establishing polarity in C. elegans embryos, encodes a putative Ser/Thr kinase that is asymmetrically distributed

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7 January 2021

Asymmetric segregation of the homeodomain protein Prospero during Drosophila development.

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7 January 2021

Asymmetric segregation of Numb and Prospero during cell division

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7 January 2021

Inscuteable and Staufen mediate asymmetric localization and segregation of prospero RNA during Drosophila neuroblast cell divisions.

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7 January 2021

Staufen-dependent localization of prospero mRNA contributes to neuroblast daughter-cell fate.

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7 January 2021

Miranda mediates asymmetric protein and RNA localization in the developing nervous system

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7 January 2021

Miranda Is Required for the Asymmetric Localization of Prospero during Mitosis in Drosophila

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7 January 2021

Miranda directs Prospero to a daughter cell during Drosophila asymmetric divisions

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7 January 2021

Asymmetric distribution of numb protein during division of the sensory organ precursor cell confers distinct fates to daughter cells

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7 January 2021

Partner of Numb colocalizes with Numb during mitosis and directs Numb asymmetric localization in Drosophila neural and muscle progenitors

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7 January 2021

prospero is expressed in neuronal precursors and encodes a nuclear protein that is involved in the control of axonal outgrowth in Drosophila

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7 January 2021

The prospero gene specifies cell fates in the drosophila central nervous system

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7 January 2021

numb, a gene required in determination of cell fate during sensory organ formation in Drosophila embryos

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7 January 2021

Inscuteable and numb mediate asymmetric muscle progenitor cell divisions during Drosophila myogenesis

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7 January 2021

Binary sibling neuronal cell fate decisions in the Drosophila embryonic central nervous system are nonstochastic and require inscuteable-mediated asymmetry of ganglion mother cells

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7 January 2021

Mesodermal cell fate decisions in Drosophila are under the control of the lineage genes numb, Notch, and sanpodo.

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7 January 2021

Control of daughter cell fates during asymmetric division: interaction of Numb and Notch

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7 January 2021

The Drosophila Numb protein inhibits signaling of the Notch receptor during cell-cell interaction in sensory organ lineage

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7 January 2021

Role of inscuteable in orienting asymmetric cell divisions in Drosophila

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7 January 2021

inscuteable, a neural precursor gene of Drosophila, encodes a candidate for a cytoskeleton adaptor protein

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7 January 2021

Rotation and asymmetry of the mitotic spindle direct asymmetric cell division in the developing central nervous system.

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7 January 2021

Bazooka recruits Inscuteable to orient asymmetric cell divisions in Drosophila neuroblasts.

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7 January 2021

Bazooka provides an apical cue for Inscuteable localization in Drosophila neuroblasts

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7 January 2021

Control of spindle orientation in Drosophila by the Par-3-related PDZ-domain protein Bazooka

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7 January 2021

armadillo, bazooka, and stardust are critical for early stages in formation of the zonula adherens and maintenance of the polarized blastoderm epithelium in Drosophila.

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7 January 2021

DmPAR-6 directs epithelial polarity and asymmetric cell division of neuroblasts in Drosophila

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7 January 2021

Drosophila atypical protein kinase C associates with Bazooka and controls polarity of epithelia and neuroblasts

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7 January 2021

Identification of Miranda protein domains regulating asymmetric cortical localization, cargo binding, and cortical release

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7 January 2021

The cell-polarity protein Par6 links Par3 and atypical protein kinase C to Cdc42

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7 January 2021

A mammalian PAR-3-PAR-6 complex implicated in Cdc42/Rac1 and aPKC signalling and cell polarity

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7 January 2021

Cell polarity: Scaffold proteins par excellence

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7 January 2021

An atypical PKC directly associates and colocalizes at the epithelial tight junction with ASIP, a mammalian homologue of Caenorhabditis elegans polarity protein PAR-3

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7 January 2021

CYK-4: A Rho family gtpase activating protein (GAP) required for central spindle formation and cytokinesis

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7 January 2021

Cell contacts orient some cell division axes in the Caenorhabditis elegans embryo

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7 January 2021

Wnt signaling polarizes an early C. elegans blastomere to distinguish endoderm from mesoderm

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7 January 2021

Wnt pathway components orient a mitotic spindle in the early Caenorhabditis elegans embryo without requiring gene transcription in the responding cell

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7 January 2021

Frizzled signalling controls orientation of asymmetric sense organ precursor cell divisions in Drosophila

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7 January 2021

Two types of asymmetric divisions in the Drosophila sensory organ precursor cell lineage

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7 January 2021

Planar polarity: out of joint?

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7 January 2021

Frizzled signaling and the developmental control of cell polarity.

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7 January 2021

A Drosophila tissue polarity locus encodes a protein containing seven potential transmembrane domains

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7 January 2021

The role of RhoA in tissue polarity and Frizzled signalling

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7 January 2021

Flamingo controls the planar polarity of sensory bristles and asymmetric division of sensory organ precursors in Drosophila.

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7 January 2021

Frizzled regulates localization of cell-fate determinants and mitotic spindle rotation during asymmetric cell division.

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7 January 2021

G proteins are required for spatial orientation of early cell cleavages in C. elegans embryos.

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7 January 2021

Protein kinase C is differentially stimulated by Wnt and Frizzled homologs in a G-protein-dependent manner

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7 January 2021

A protein complex containing Inscuteable and the Galpha-binding protein Pins orients asymmetric cell divisions in Drosophila

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7 January 2021

Analysis of partner of inscuteable, a novel player of Drosophila asymmetric divisions, reveals two distinct steps in inscuteable apical localization

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7 January 2021

Rapsynoid/partner of inscuteable controls asymmetric division of larval neuroblasts in Drosophila.

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7 January 2021

The GoLoco motif: a Galphai/o binding motif and potential guanine-nucleotide exchange factor

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7 January 2021

Receptor-independent activators of heterotrimeric G-protein signaling pathways

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7 January 2021

G protein signaling events are activated at the leading edge of chemotactic cells

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7 January 2021

Cell polarity in yeast

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7 January 2021

The PIE-1 protein and germline specification in C. elegans embryos

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7 January 2021

Repression of gene expression in the embryonic germ lineage of C. elegans

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7 January 2021

Asymmetric segregation of PIE-1 in C. elegans is mediated by two complementary mechanisms that act through separate PIE-1 protein domains

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7 January 2021

Modes of protein movement that lead to the asymmetric localization of partner of Numb during Drosophila neuroblast division

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7 January 2021

The tumour-suppressor genes lgl and dlg regulate basal protein targeting in Drosophila neuroblasts

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7 January 2021

Role of cortical tumour-suppressor proteins in asymmetric division of Drosophila neuroblast

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7 January 2021

Dlg protein is required for junction structure, cell polarity, and proliferation control in Drosophila epithelia

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7 January 2021

Cooperative regulation of cell polarity and growth by Drosophila tumor suppressors

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7 January 2021

The Drosophila lethal(2)giant larvae tumor suppressor protein is a component of the cytoskeleton.

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7 January 2021

The discs-large tumor suppressor gene of Drosophila encodes a guanylate kinase homolog localized at septate junctions

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7 January 2021

The Drosophila lethal(2)giant larvae tumor suppressor protein forms homo-oligomers and is associated with nonmuscle myosin II heavy chain

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7 January 2021

What is Drosophila telling us about cancer?

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7 January 2021

Cleavage orientation and the asymmetric inheritance of notchl immunoreactivity in mammalian neurogenesis

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7 January 2021

Asymmetric localization of a mammalian numb homolog during mouse cortical neurogenesis

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7 January 2021

NUMB localizes in the basal cortex of mitotic avian neuroepithelial cells and modulates neuronal differentiation by binding to NOTCH-1.

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7 January 2021

Mouse numb is an essential gene involved in cortical neurogenesis

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7 January 2021

Identification of a neural stem cell in the adult mammalian central nervous system

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7 January 2021

Subventricular zone astrocytes are neural stem cells in the adult mammalian brain

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7 January 2021

Centrosome movement in the early divisions of Caenorhabditis elegans: a cortical site determining centrosome position

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7 January 2021

The Drosophila homolog of C. elegans PAR-1 organizes the oocyte cytoskeleton and directs oskar mRNA localization to the posterior pole

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7 January 2021

Mammalian homologues of C. elegans PAR-1 are asymmetrically localized in epithelial cells and may influence their polarity

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7 January 2021

par-2, a gene required for blastomere asymmetry in Caenorhabditis elegans, encodes zinc-finger and ATP-binding motifs

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7 January 2021

A Caenorhabditis elegans prospero homologue defines a novel domain

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7 January 2021

Prox 1, a prospero-related homeobox gene expressed during mouse development

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7 January 2021

Identifiers

DOI

10.1038/35048085

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Dimensions Publication ID

1 August 2017

1033146752

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