(Q34262782)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22437714%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

title

Evidence that a 'dynamic knockout' in Escherichia coli dihydrofolate reductase does not affect the chemical step of catalysis (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22437714%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22437714%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

Enas M Behiry

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22437714%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

Jiannan Guo

series ordinal

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22437714%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

Rudolf K Allemann

series ordinal

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22437714%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

publication date

11 March 2012

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22437714%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22437714%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

volume

1 reference

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26 January 2020

issue

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22437714%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

page(s)

292-297

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22437714%20AND%20SRC:MED&resulttype=core&format=json

A 21st century revisionist's view at a turning point in enzymology

26 January 2020

cites work

1 reference

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Probing coupled motions in enzymatic hydrogen tunnelling reactions

21 January 2018

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Atomic description of an enzyme reaction dominated by proton tunneling

21 January 2018

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Computational and theoretical methods to explore the relation between enzyme dynamics and catalysis

21 January 2018

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Dynamical contributions to enzyme catalysis: critical tests of a popular hypothesis

21 January 2018

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Protein dynamics and enzyme catalysis: insights from simulations

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Enzymology takes a quantum leap forward

21 January 2018

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Evidence to support the hypothesis that promoting vibrations enhance the rate of an enzyme catalyzed H-tunneling reaction

21 January 2018

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Enzymatic transition states and dynamic motion in barrier crossing

21 January 2018

1 reference

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Slow conformational motions that favor sub-picosecond motions important for catalysis

21 January 2018

1 reference

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Dynamic personalities of proteins

21 January 2018

1 reference

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A compelling experimental test of the hypothesis that enzymes have evolved to enhance quantum mechanical tunneling in hydrogen transfer reactions: the beta-neopentylcobalamin system combined with prior adocobalamin data

21 January 2018

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The first experimental test of the hypothesis that enzymes have evolved to enhance hydrogen tunneling

21 January 2018

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An Analysis of All the Relevant Facts and Arguments Indicates that Enzyme Catalysis Does Not Involve Large Contributions from Nuclear Tunneling

21 January 2018

1 reference

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Enzyme millisecond conformational dynamics do not catalyze the chemical step

21 January 2018

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Origin of the temperature dependence of isotope effects in enzymatic reactions: the case of dihydrofolate reductase

21 January 2018

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Effect of pH on hydride transfer by Escherichia coli dihydrofolate reductase.

21 January 2018

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Tunneling and coupled motion in the Escherichia coli dihydrofolate reductase catalysis

21 January 2018

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Enzyme dynamics and hydrogen tunnelling in a thermophilic alcohol dehydrogenase.

21 January 2018

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Oxygen- and temperature-dependent kinetic isotope effects in choline oxidase: correlating reversible hydride transfer with environmentally enhanced tunneling

21 January 2018

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Structural and mechanistic aspects of flavoproteins: probes of hydrogen tunnelling

21 January 2018

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Loop and subdomain movements in the mechanism of Escherichia coli dihydrofolate reductase: crystallographic evidence

21 January 2018

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A dynamic knockout reveals that conformational fluctuations influence the chemical step of enzyme catalysis

21 January 2018

1 reference

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Catalysis by dihydrofolate reductase and other enzymes arises from electrostatic preorganization, not conformational motions

21 January 2018

1 reference

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Pivotal role of Gly 121 in dihydrofolate reductase from Escherichia coli: the altered structure of a mutant enzyme may form the basis of its diminished catalytic performance

21 January 2018

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Construction and evaluation of the kinetic scheme associated with dihydrofolate reductase from Escherichia coli

21 January 2018

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Hydride transfer during catalysis by dihydrofolate reductase from Thermotoga maritima

21 January 2018

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The role of large-scale motions in catalysis by dihydrofolate reductase.

21 January 2018

1 reference

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Functionally important conformations of the Met20 loop in dihydrofolate reductase are populated by rapid thermal fluctuations

21 January 2018

1 reference

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Backbone dynamics in dihydrofolate reductase complexes: role of loop flexibility in the catalytic mechanism

21 January 2018

1 reference

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The temperature dependence of the kinetic isotope effects of dihydrofolate reductase from Thermotoga maritima is influenced by intersubunit interactions

21 January 2018

1 reference

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Solvent effects on catalysis by Escherichia coli dihydrofolate reductase

21 January 2018

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Solvent effects on environmentally coupled hydrogen tunnelling during catalysis by dihydrofolate reductase from Thermotoga maritima

21 January 2018

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The catalytic effect of dihydrofolate reductase and its mutants is determined by reorganization energies

21 January 2018

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Coupling of protein motions and hydrogen transfer during catalysis by Escherichia coli dihydrofolate reductase

21 January 2018

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Kinetic mechanism of the reaction catalyzed by dihydrofolate reductase from Escherichia coli.

21 January 2018

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Temperature dependence of acidity constants, a tool to affect separation selectivity in capillary electrophoresis.

21 January 2018

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Crystalline Dihydropteroylglutamic Acid

21 January 2018

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Nuclear quantum tunneling in the light-activated enzyme protochlorophyllide oxidoreductase

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22437714

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Heavy atom motions and tunneling in hydrogen transfer reactions: the importance of the pre-tunneling state

1 reference

https://api.crossref.org/works/10.1038%2FNCHEM.1296