(Q34245432)

31 July 2017

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title

Receptor clustering and transmembrane signaling in T cells (English)

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31 July 2017

main subject

transmembrane protein

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author name string

Cochran JR

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31 July 2017

Aivazian D

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31 July 2017

Cameron TO

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31 July 2017

Stern LJ

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31 July 2017

publication date

1 May 2001

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Trends in Biochemical Sciences

31 July 2017

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inferred from page(s)

published in

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31 July 2017

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31 July 2017

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31 July 2017

page(s)

304-310

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Protein tyrosine kinase structure and function

31 July 2017

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T cell receptor-MHC interactions up close

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T cell antigen receptor signal transduction

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Signaling takes shape in the immune system

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Both high and low avidity antibodies to the T cell receptor can have agonist or antagonist activity

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The cytoplasmic domain of the T cell receptor zeta chain is sufficient to couple to receptor-associated signal transduction pathways

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T-cell and basophil activation through the cytoplasmic tail of T-cell-receptor zeta family proteins.

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Controlling Signal Transduction with Synthetic Ligands

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From TCR Engagement to T Cell Activation

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Altered peptide ligand-induced partial T cell activation: molecular mechanisms and role in T cell biology

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A new look at T cells

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MHC-based diagnostics and therapeutics - clinical applications for disease-linked genes

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Dimerization of soluble major histocompatibility complex-peptide complexes is sufficient for activation of T cell hybridoma and induction of unresponsiveness

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7 January 2021

Potent T cell activation with dimeric peptide-major histocompatibility complex class II ligand: the role of CD4 coreceptor

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7 January 2021

Kinetics of T-cell receptor binding by bivalent HLA-DR. Peptide complexes that activate antigen-specific human T-cells

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Antigen-specific signaling by a soluble, dimeric peptide/major histocompatibility complex class II/Fc chimera leading to T helper cell type 2 differentiation

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7 January 2021

Initiation of signal transduction through the T cell receptor requires the multivalent engagement of peptide/MHC ligands [corrected]

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CD8 Expression Allows T Cell Signaling by Monomeric Peptide-MHC Complexes

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A diverse set of oligomeric class II MHC-peptide complexes for probing T-cell receptor interactions

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The relationship of MHC-peptide binding and T cell activation probed using chemically defined MHC class II oligomers

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Four A6-TCR/peptide/HLA-A2 structures that generate very different T cell signals are nearly identical

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7 January 2021

Cutting edge: detection of antigen-specific CD4+ T cells by HLA-DR1 oligomers is dependent on the T cell activation state

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7 January 2021

Ligands for the T-cell receptor: hard times for avidity models

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7 January 2021

An antagonist peptide-EPO receptor complex suggests that receptor dimerization is not sufficient for activation

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7 January 2021

Qualitative and quantitative differences in T cell receptor binding of agonist and antagonist ligands.

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7 January 2021

The role of T-cell receptor dimerization in T-cell activation.

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Multivalent structure of an alphabetaT cell receptor

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Three-dimensional segregation of supramolecular activation clusters in T cells

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7 January 2021

The immunological synapse: a molecular machine controlling T cell activation

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7 January 2021

T-cell signaling: the importance of receptor clustering

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Concentration of MHC class II molecules in lipid rafts facilitates antigen presentation

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7 January 2021

T lymphocyte costimulation mediated by reorganization of membrane microdomains

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7 January 2021

A receptor/cytoskeletal movement triggered by costimulation during T cell activation

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7 January 2021

T cell activation determined by T cell receptor number and tunable thresholds.

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Cytoskeletal polarization and redistribution of cell-surface molecules during T cell antigen recognition

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7 January 2021

Evidence that a single peptide-MHC complex on a target cell can elicit a cytolytic T cell response

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7 January 2021

Determination of the relationship between T cell responsiveness and the number of MHC-peptide complexes using specific monoclonal antibodies

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7 January 2021

Differential clustering of CD4 and CD3zeta during T cell recognition

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7 January 2021

Membrane rafts and signaling by the multichain immune recognition receptors

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7 January 2021

ZAP-70 is constitutively associated with tyrosine-phosphorylated TCR ζ in murine thymocytes and lymph node T cells

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7 January 2021

Making the T cell receptor go the distance: a topological view of T cell activation

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7 January 2021

Phosphorylation of T cell receptor zeta is regulated by a lipid dependent folding transition

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7 January 2021

The immunological synapse and the actin cytoskeleton: molecular hardware for T cell signaling.

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7 January 2021

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Identifiers

DOI

1 reference

31 July 2017

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