(Q34195822)

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Calcium Upregulation by Percutaneous Administration of Gene Therapy in Cardiac Disease (CUPID): a phase 2 trial of intracoronary gene therapy of sarcoplasmic reticulum Ca2+-ATPase in patients with advanced heart failure

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Europe PubMed Central

PMC publication ID

30 June 2018

http://europepmc.org/abstract/PMC/5843948

Calcium Upregulation by Percutaneous Administration of Gene Therapy in Cardiac Disease (CUPID): a phase 2 trial of intracoronary gene therapy of sarcoplasmic reticulum Ca2+-ATPase in patients with advanced heart failure (English)

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Europe PubMed Central

PMC publication ID

30 June 2018

http://europepmc.org/abstract/PMC/5843948

phase II clinical trial

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Europe PubMed Central

PMC publication ID

30 June 2018

http://europepmc.org/abstract/PMC/5843948

Donna M. Mancini

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Donna Mancini

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Europe PubMed Central

PMC publication ID

30 June 2018

http://europepmc.org/abstract/PMC/5843948

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Barry Greenberg

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Europe PubMed Central

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30 June 2018

http://europepmc.org/abstract/PMC/5843948

Thomas Cappola

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Europe PubMed Central

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30 June 2018

http://europepmc.org/abstract/PMC/5843948

Daniel F Pauly

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Europe PubMed Central

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30 June 2018

http://europepmc.org/abstract/PMC/5843948

Brian Jaski

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Europe PubMed Central

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30 June 2018

http://europepmc.org/abstract/PMC/5843948

Alex Yaroshinsky

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Europe PubMed Central

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30 June 2018

http://europepmc.org/abstract/PMC/5843948

Krisztina M Zsebo

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Europe PubMed Central

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30 June 2018

http://europepmc.org/abstract/PMC/5843948

Howard Dittrich

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Europe PubMed Central

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30 June 2018

http://europepmc.org/abstract/PMC/5843948

Roger J Hajjar

10

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Europe PubMed Central

PMC publication ID

30 June 2018

http://europepmc.org/abstract/PMC/5843948

Calcium Upregulation by Percutaneous Administration of Gene Therapy in Cardiac Disease (CUPID) Investigators

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Europe PubMed Central

PMC publication ID

30 June 2018

http://europepmc.org/abstract/PMC/5843948

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publication date

27 June 2011

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Europe PubMed Central

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30 June 2018

http://europepmc.org/abstract/PMC/5843948

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Europe PubMed Central

PMC publication ID

30 June 2018

http://europepmc.org/abstract/PMC/5843948

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Europe PubMed Central

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30 June 2018

http://europepmc.org/abstract/PMC/5843948

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Europe PubMed Central

PMC publication ID

30 June 2018

http://europepmc.org/abstract/PMC/5843948

304-313

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Europe PubMed Central

PMC publication ID

30 June 2018

http://europepmc.org/abstract/PMC/5843948

Heart disease and stroke statistics--2009 update: a report from the American Heart Association Statistics Committee and Stroke Statistics Subcommittee

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5843948

5 July 2018

SERCA2a gene therapy for heart failure: ready for primetime?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5843948

5 July 2018

Existence of transient functional double-stranded DNA intermediates during recombinant AAV transduction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5843948

5 July 2018

Excitation-contraction coupling and mitochondrial energetics

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5843948

5 July 2018

Targeted high-efficiency, homogeneous myocardial gene transfer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5843948

5 July 2018

Gene therapy in the treatment of heart failure

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5843948

5 July 2018

Restoration of mechanical and energetic function in failing aortic-banded rat hearts by gene transfer of calcium cycling proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5843948

5 July 2018

Long-term suppression of experimental arthritis following intramuscular administration of a pseudotyped AAV2/1-TNFR:Fc Vector

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5843948

5 July 2018

SERCA2a in heart failure: role and therapeutic prospects

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5843948

5 July 2018

Clinical relevance of biological variation: the lesson of brain natriuretic peptide (BNP) and NT-proBNP assay.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5843948

5 July 2018

Characterization of adeno-associated virus genomes isolated from human tissues

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5843948

5 July 2018

Adeno-associated virus vectors in clinical trials

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5843948

5 July 2018

Gene transfer in cardiac myocytes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5843948

5 July 2018

Cardiac resynchronization in chronic heart failure

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5843948

5 July 2018

Differential activation of innate immune responses by adenovirus and adeno-associated virus vectors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5843948

5 July 2018

Improvement in survival and cardiac metabolism after gene transfer of sarcoplasmic reticulum Ca(2+)-ATPase in a rat model of heart failure

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5843948

5 July 2018

Monoclonal antibodies against the adeno-associated virus type 2 (AAV-2) capsid: epitope mapping and identification of capsid domains involved in AAV-2-cell interaction and neutralization of AAV-2 infection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5843948

5 July 2018

Epitope mapping of human anti-adeno-associated virus type 2 neutralizing antibodies: implications for gene therapy and virus structure

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5843948

5 July 2018

Linking clinical relevance and statistical significance in evaluating intra-individual changes in health-related quality of life

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5843948

5 July 2018

Implantable left ventricular assist devices.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5843948

5 July 2018

Modulation of ventricular function through gene transfer in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5843948

5 July 2018

Recirculating cardiac delivery of AAV2/1SERCA2a improves myocardial function in an experimental model of heart failure in large animals

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5843948

28 October 2018

Design of a phase 1/2 trial of intracoronary administration of AAV1/SERCA2a in patients with heart failure.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5843948

28 October 2018

Impact of cardiac resynchronization therapy on exercise performance, functional capacity, and quality of life in systolic heart failure with QRS prolongation: COMPANION trial sub-study

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5843948

28 October 2018

Heart failure: a silver bullet to treat heart failure

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5843948

28 October 2018

Evidence of multiyear factor IX expression by AAV-mediated gene transfer to skeletal muscle in an individual with severe hemophilia B.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5843948

28 October 2018

Diastolic dysfunction in human cardiac allografts is related with reduced SERCA2a gene expression.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5843948

28 October 2018

Human immunoglobulin inhibits liver transduction by AAV vectors at low AAV2 neutralizing titers in SCID mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5843948

28 October 2018

Prognostic impact of plasma N-terminal pro-brain natriuretic peptide in severe chronic congestive heart failure: a substudy of the Carvedilol Prospective Randomized Cumulative Survival (COPERNICUS) trial

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5843948

28 October 2018

Clinical recovery from end-stage heart failure using left-ventricular assist device and pharmacological therapy correlates with increased sarcoplasmic reticulum calcium content but not with regression of cellular hypertrophy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5843948

28 October 2018

Self-rating of quality of life provides additional prognostic information in heart failure. Insights into the EPICAL study.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5843948

28 October 2018

Prognostic value of low-dose dobutamine echocardiography in patients with idiopathic dilated cardiomyopathy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5843948

28 October 2018

Further evidence supporting an SEM-based criterion for identifying meaningful intra-individual changes in health-related quality of life.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5843948

28 October 2018

Successes and failures of current treatment of heart failure

1 reference

https://pubmed.ncbi.nlm.nih.gov/21709064

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Relation between myocardial function and expression of sarcoplasmic reticulum Ca(2+)-ATPase in failing and nonfailing human myocardium

1 reference

https://pubmed.ncbi.nlm.nih.gov/21709064

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Alterations in sarcoplasmic reticulum gene expression in human heart failure. A possible mechanism for alterations in systolic and diastolic properties of the failing myocardium

1 reference

https://pubmed.ncbi.nlm.nih.gov/21709064

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The reproducibility and sensitivity of the 6-min walk test in elderly patients with chronic heart failure

1 reference

https://pubmed.ncbi.nlm.nih.gov/21709064

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Function of the sarcoplasmic reticulum and expression of its Ca2(+)-ATPase gene in pressure overload-induced cardiac hypertrophy in the rat

1 reference

https://pubmed.ncbi.nlm.nih.gov/21709064

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

High intraindividual variation of B-type natriuretic peptide (BNP) and amino-terminal proBNP in patients with stable chronic heart failure

1 reference

https://pubmed.ncbi.nlm.nih.gov/21709064

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Overwhelming evidence of the beneficial effects of SERCA gene transfer in heart failure

1 reference

https://pubmed.ncbi.nlm.nih.gov/21709064

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

[Serum NT-proBNP levels are a prognostic predictor in patients with advanced heart failure]

1 reference

https://pubmed.ncbi.nlm.nih.gov/21709064

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Echocardiographic predictors of morbidity and mortality in patients with advanced heart failure: the Beta-blocker Evaluation of Survival Trial (BEST)

1 reference

https://pubmed.ncbi.nlm.nih.gov/21709064

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Unchanged Protein Levels of SERCA II and Phospholamban but Reduced Ca 2+ Uptake and Ca 2+ -ATPase Activity of Cardiac Sarcoplasmic Reticulum From Dilated Cardiomyopathy Patients Compared With Patients With Nonfailing Hearts

1 reference

https://pubmed.ncbi.nlm.nih.gov/21709064

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reversal of cardiac dysfunction after long-term expression of SERCA2a by gene transfer in a pre-clinical model of heart failure

1 reference

https://pubmed.ncbi.nlm.nih.gov/21709064

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1161/CIRCULATIONAHA.111.022889

1 reference

Europe PubMed Central

PMC publication ID

30 June 2018

http://europepmc.org/abstract/PMC/5843948

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

30 June 2018

http://europepmc.org/abstract/PMC/5843948

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

30 June 2018

http://europepmc.org/abstract/PMC/5843948

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