(Q34145600)

31 July 2017

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title

Protein import into and across the mitochondrial inner membrane: role of the TIM23 and TIM22 translocons (English)

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TIM22 mitochondrial import inner membrane insertion complex

31 July 2017

main subject

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Gene Ontology release 2020-05-02

Robert E Jensen

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31 July 2017

Cory D Dunn

series ordinal

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31 July 2017

language of work or name

English

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publication date

1 September 2002

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Biochimica et Biophysica Acta

31 July 2017

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inferred from page(s)

published in

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31 July 2017

volume

1592

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31 July 2017

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31 July 2017

page(s)

25-34

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The mitochondrial import machinery for preproteins

31 July 2017

cites work

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900261-6

7 January 2021

Protein import into mitochondria

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900261-6

7 January 2021

Identification of the essential yeast protein MIM17, an integral mitochondrial inner membrane protein involved in protein import

1 reference

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7 January 2021

SMS1, a high-copy suppressor of the yeast mas6 mutant, encodes an essential inner membrane protein required for mitochondrial protein import

1 reference

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7 January 2021

MAS6 encodes an essential inner membrane component of the yeast mitochondrial protein import pathway

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https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900261-6

7 January 2021

Identification of MIM23, a putative component of the protein import machinery of the mitochondrial inner membrane

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900261-6

7 January 2021

Characterization of the mitochondrial inner membrane translocase complex: the Tim23p hydrophobic domain interacts with Tim17p but not with other Tim23p molecules

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900261-6

7 January 2021

The MIM complex mediates preprotein translocationacross the mitochondrial inner membrane and couples it to the mt-Hsp70/ATP driving system

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900261-6

7 January 2021

The Tim core complex defines the number of mitochondrial translocation contact sites and can hold arrested preproteins in the absence of matrix Hsp70-Tim44.

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900261-6

7 January 2021

The TIM17.23 preprotein translocase of mitochondria: composition and function in protein transport into the matrix

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900261-6

7 January 2021

The polytopic mitochondrial inner membrane proteins MIM17 and MIM23 operate at the same preprotein import site

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900261-6

7 January 2021

Identification of a 45-kDa protein at the protein import site of the yeast mitochondrial inner membrane

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900261-6

7 January 2021

Translocation arrest of an intramitochondrial sorting signal next to Tim11 at the inner-membrane import site

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900261-6

7 January 2021

A GTP-dependent "push" is generally required for efficient protein translocation across the mitochondrial inner membrane into the matrix

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900261-6

7 January 2021

Functional and physical interactions of components of the yeast mitochondrial inner-membrane import machinery (MIM)

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900261-6

7 January 2021

Tim23, a protein import component of the mitochondrial inner membrane, is required for normal activity of the multiple conductance channel, MCC.

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900261-6

7 January 2021

A presequence- and voltage-sensitive channel of the mitochondrial preprotein translocase formed by Tim23.

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900261-6

7 January 2021

Role of Tim23 as voltage sensor and presequence receptor in protein import into mitochondria

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900261-6

7 January 2021

A dual role for mitochondrial heat shock protein 70 in membrane translocation of preproteins

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900261-6

7 January 2021

Requirement for hsp70 in the mitochondrial matrix for translocation and folding of precursor proteins

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https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900261-6

7 January 2021

Requirement of a Membrane Potential for the Posttranslational Transfer of Proteins into Mitochondsria

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7 January 2021

Transport of F1-ATPase subunit beta into mitochondria depends on both a membrane potential and nucleoside triphosphates

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900261-6

7 January 2021

Mitochondrial protein import: biochemical and genetic evidence for interaction of matrix hsp70 and the inner membrane protein MIM44

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900261-6

7 January 2021

Mitochondrial Hsp70/MIM44 complex facilitates protein import

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900261-6

7 January 2021

Dynamic interaction between Isp45 and mitochondrial hsp70 in the protein import system of the yeast mitochondrial inner membrane

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900261-6

7 January 2021

Protein translocation: is Hsp70 pulling my chain?

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900261-6

7 January 2021

Disrupted yeast mitochondria can import precursor proteins directly through their inner membrane

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900261-6

7 January 2021

Translocation and insertion of precursor proteins into isolated outer membranes of mitochondria

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900261-6

7 January 2021

Tim23 links the inner and outer mitochondrial membranes.

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900261-6

7 January 2021

Sorting of D-lactate dehydrogenase to the inner membrane of mitochondria. Analysis of topogenic signal and energetic requirements

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900261-6

7 January 2021

Removal of a hydrophobic domain within the mature portion of a mitochondrial inner membrane protein causes its mislocalization to the matrix

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900261-6

7 January 2021

N-terminal tail export from the mitochondrial matrix. Adherence to the prokaryotic "positive-inside" rule of membrane protein topology

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900261-6

7 January 2021

Conservative sorting of F0-ATPase subunit 9: export from matrix requires delta pH across inner membrane and matrix ATP

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900261-6

7 January 2021

Two distinct and independent mitochondrial targeting signals function in the sorting of an inner membrane protein, cytochrome c1

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900261-6

7 January 2021

The sorting signal of cytochrome b2 promotes early divergence from the general mitochondrial import pathway and restricts the unfoldase activity of matrix Hsp70.

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900261-6

7 January 2021

Cytochromes c1 and b2 are sorted to the intermembrane space of yeast mitochondria by a stop-transfer mechanism

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900261-6

7 January 2021

A mitochondrial protease with two catalytic subunits of nonoverlapping specificities.

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900261-6

7 January 2021

Mitochondrial inner membrane protease 1 of Saccharomyces cerevisiae shows sequence similarity to the Escherichia coli leader peptidase

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900261-6

7 January 2021

Topogenesis of inner membrane proteins of mitochondria

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900261-6

7 January 2021

Membrane potential-driven protein import into mitochondria. The sorting sequence of cytochrome b(2) modulates the deltapsi-dependence of translocation of the matrix-targeting sequence

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900261-6

7 January 2021

N-terminal Hydrophobic Sorting Signals of Preproteins Confer Mitochondrial hsp70 Independence for Import into Mitochondria

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900261-6

7 January 2021

Presequence and mature part of preproteins strongly influence the dependence of mitochondrial protein import on heat shock protein 70 in the matrix

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900261-6

7 January 2021

A mutant form of mitochondrial GrpE suppresses the sorting defect caused by an alteration in the presequence of cytochrome b2

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900261-6

7 January 2021

Yeast mitochondrial F1F0-ATPase: the novel subunit e is identical to Tim11.

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900261-6

7 January 2021

The cotranslational integration of membrane proteins into the phospholipid bilayer is a multistep process

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900261-6

7 January 2021

Molecular mechanism of membrane protein integration into the endoplasmic reticulum

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900261-6

7 January 2021

Import of carrier proteins into the mitochondrial inner membrane mediated by Tim22.

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900261-6

7 January 2021

Tim22, the essential core of the mitochondrial protein insertion complex, forms a voltage-activated and signal-gated channel

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900261-6

7 January 2021

The Tim54p-Tim22p complex mediates insertion of proteins into the mitochondrial inner membrane

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900261-6

7 January 2021

Tim18p is a new component of the Tim54p-Tim22p translocon in the mitochondrial inner membrane

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900261-6

7 January 2021

Tim18p, a new subunit of the TIM22 complex that mediates insertion of imported proteins into the yeast mitochondrial inner membrane

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900261-6

7 January 2021

MMM1 encodes a mitochondrial outer membrane protein essential for establishing and maintaining the structure of yeast mitochondria

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900261-6

7 January 2021

Mmm1p, a mitochondrial outer membrane protein, is connected to mitochondrial DNA (mtDNA) nucleoids and required for mtDNA stability

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900261-6

7 January 2021

The Saccharomyces cerevisiae succinate dehydrogenase anchor subunit, Sdh4p: mutations at the C-terminal lys-132 perturb the hydrophobic domain

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900261-6

7 January 2021

Carrier protein import into mitochondria mediated by the intermembrane proteins Tim10/Mrs11 and Tim12/Mrs5.

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900261-6

7 January 2021

Tim9p, an essential partner subunit of Tim10p for the import of mitochondrial carrier proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900261-6

7 January 2021

Import of mitochondrial carriers mediated by essential proteins of the intermembrane space

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900261-6

7 January 2021

Tim9, a new component of the TIM22.54 translocase in mitochondria

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900261-6

7 January 2021

Human deafness dystonia syndrome is a mitochondrial disease

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900261-6

7 January 2021

The Tim9p-Tim10p complex binds to the transmembrane domains of the ADP/ATP carrier

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900261-6

7 January 2021

The DNA helicase, Hmi1p, is transported into mitochondria by a C-terminal cleavable targeting signal

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900261-6

7 January 2021

Role of the chaperonin cofactor Hsp10 in protein folding and sorting in yeast mitochondria

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900261-6

7 January 2021

Phylogenetic classification of the mitochondrial carrier family of Saccharomyces cerevisiae

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900261-6

7 January 2021

Mitochondrial metabolite transporters.

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900261-6

7 January 2021

Tim23p contains separate and distinct signals for targeting to mitochondria and insertion into the inner membrane

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900261-6

7 January 2021

Transport of the ADP/ATP carrier of mitochondria from the TOM complex to the TIM22.54 complex

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900261-6

7 January 2021

Functional staging of ADP/ATP carrier translocation across the outer mitochondrial membrane

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900261-6

7 January 2021

The three modules of ADP/ATP carrier cooperate in receptor recruitment and translocation into mitochondria

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900261-6

7 January 2021

Two intermembrane space TIM complexes interact with different domains of Tim23p during its import into mitochondria

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900261-6

7 January 2021

The role of the TIM8-13 complex in the import of Tim23 into mitochondria

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900261-6

7 January 2021

Secretory proteins move through the endoplasmic reticulum membrane via an aqueous, gated pore.

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900261-6

7 January 2021

Mitochondrial targeting sequences may form amphiphilic helices

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900261-6

7 January 2021

10.1016/S0167-4889(02)00261-6

Identifiers

DOI

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31 July 2017

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