(Q34125750)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11978855%20AND%20SRC:MED&resulttype=core&format=json

10 December 2019

title

Stress-induced deoxycorticosterone-derived neurosteroids modulate GABA(A) receptor function and seizure susceptibility (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11978855%20AND%20SRC:MED&resulttype=core&format=json

10 December 2019

1 reference

Doodipala S Reddy

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11978855%20AND%20SRC:MED&resulttype=core&format=json

10 December 2019

Michael A Rogawski

series ordinal

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11978855%20AND%20SRC:MED&resulttype=core&format=json

10 December 2019

language of work or name

English

0 references

publication date

1 May 2002

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11978855%20AND%20SRC:MED&resulttype=core&format=json

10 December 2019

published in

Journal of Neuroscience

1 reference

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10 December 2019

volume

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11978855%20AND%20SRC:MED&resulttype=core&format=json

10 December 2019

issue

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11978855%20AND%20SRC:MED&resulttype=core&format=json

10 December 2019

page(s)

3795-3805

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11978855%20AND%20SRC:MED&resulttype=core&format=json

Finasteride, a 5alpha-reductase inhibitor, blocks the anticonvulsant activity of progesterone in mice.

10 December 2019

cites work

1 reference

12 December 2020

Swim stress alters the behavioural response of mice to GABA-related and some GABA-unrelated convulsants

1 reference

12 December 2020

Enhanced anticonvulsant activity of ganaxolone after neurosteroid withdrawal in a rat model of catamenial epilepsy.

1 reference

12 December 2020

Synthesis, metabolism, and pharmacological activity of 3 alpha-hydroxy steroids which potentiate GABA-receptor-mediated chloride ion uptake in rat cerebral cortical synaptoneurosomes

1 reference

12 December 2020

Conversion of progesterone-1,2-3H to 5β-pregnane-3,20-dione by brain tissue

1 reference

12 December 2020

Anxiolytic effects of 3α-hydroxy-5α[β]-pregnan-20-one: endogenous metabolites of progesterone that are active at the GABAA receptor

1 reference

12 December 2020

Withdrawal from 3alpha-OH-5alpha-pregnan-20-One using a pseudopregnancy model alters the kinetics of hippocampal GABAA-gated current and increases the GABAA receptor alpha4 subunit in association with increased anxiety.

1 reference

12 December 2020

Antiepileptic effects of tiagabine, a selective GABA uptake inhibitor, in the rat kindling model of temporal lobe epilepsy

1 reference

12 December 2020

Indomethacin-sensitive 3 alpha-hydroxysteroid dehydrogenase in rat tissues

1 reference

12 December 2020

Steroid hormone metabolites are barbiturate-like modulators of the GABA receptor

1 reference

12 December 2020

Inhibition of a major NAD(P)-linked oxidoreductase from rat liver cytosol by steroidal and nonsteroidal anti-inflammatory agents and by prostaglandins

1 reference

12 December 2020

The effects of inhibitors of GABAergic transmission and stress on brain and plasma allopregnanolone concentrations

1 reference

12 December 2020

Neuroactive steroids protect against pilocarpine- and kainic acid-induced limbic seizures and status epilepticus in mice

1 reference

12 December 2020

Neurosteroid withdrawal model of perimenstrual catamenial epilepsy.

1 reference

12 December 2020

A new device for the rapid measurement of impaired motor function in mice

1 reference

12 December 2020

Development of neurosteroid-based novel psychotropic drugs.

1 reference

12 December 2020

Time-dependent changes in rat brain neuroactive steroid concentrations and GABAA receptor function after acute stress

1 reference

12 December 2020

Antiepileptic drugs: pharmacological mechanisms and clinical efficacy with consideration of promising developmental stage compounds

1 reference

12 December 2020

Neurosteroids and GABAA receptor function.

1 reference

12 December 2020

Genomic organization of a human 5beta-reductase and its pseudogene and substrate selectivity of the expressed enzyme.

1 reference

12 December 2020

Tissue distribution and kinetic characteristics of rat steroid 5 alpha-reductase isozymes. Evidence for distinct physiological functions

1 reference

12 December 2020

Steroid 5 alpha-reductase type 1 immunolocalized in the adrenal gland of normal, gonadectomized, and sex hormone-supplemented rats

1 reference

12 December 2020

Stress-induced elevations of gamma-aminobutyric acid type A receptor-active steroids in the rat brain

1 reference

12 December 2020

Anticonvulsive effect of swim stress in mice

1 reference

12 December 2020

Can emotions precipitate seizures--a review of the question

1 reference

12 December 2020

Regional distribution of cytosolic and particulate 5alpha-dihydroprogesterone 3alpha-hydroxysteroid oxidoreductases in female rat brain

1 reference

12 December 2020

Steroid-induced convulsions in experimental animals

1 reference

12 December 2020

Anticonvulsant activity of neurosteroids: correlation with gamma-aminobutyric acid-evoked chloride current potentiation

1 reference

12 December 2020

Acute and chronic effects of the synthetic neuroactive steroid, ganaxolone, against the convulsive and lethal effects of pentylenetetrazol in seizure-kindled mice: comparison with diazepam and valproate

1 reference

12 December 2020

Bidirectional effects of the neuroactive steroid tetrahydrodeoxycorticosterone on GABA-activated Cl- currents in cultured rat hypothalamic neurons

1 reference

12 December 2020

Rat hippocampal neurons in culture: responses to electrical and chemical stimuli

1 reference

12 December 2020

Effect of cortisol on the excitability of limbic structures of the brain in freely moving rats

1 reference

12 December 2020

Enhanced anticonvulsant activity of neuroactive steroids in a rat model of catamenial epilepsy.

1 reference

12 December 2020

Expression of 5alpha-reductase and 3alpha-hydroxisteroid oxidoreductase in the hippocampus of patients with chronic temporal lobe epilepsy

1 reference

12 December 2020

Distribution of seizure precipitants among epilepsy syndromes

1 reference

12 December 2020

The Contribution of the Zona Fasciculata and Glomerulosa to Plasma 11-Deoxycorticosterone Levels in Man

1 reference

12 December 2020

Inhibition of rat alpha-reductases by finasteride: evidence for isozyme differences in the mechanism of inhibition

1 reference

12 December 2020

Purification and properties of 3 alpha-hydroxysteroid dehydrogenase from rat brain cytosol. Inhibition by nonsteroidal anti-inflammatory drugs and progestins.

1 reference

12 December 2020

High frequency electro-shock seizures and their antagonism in developing mice. 3. Effects of cortisol, corticosterone, deoxycorticosterone, dexamethasone and a synthetic corticotropine

1 reference

12 December 2020

Steroid 5 alpha-reductase: two genes/two enzymes

1 reference

12 December 2020

Structure-activity relationships for steroid interaction with the gamma-aminobutyric acidA receptor complex

1 reference

12 December 2020

Effect of drum stress on maximal electroconvulsive seizure latency in mice

1 reference

12 December 2020

Sulfated and unsulfated steroids modulate gamma-aminobutyric acidA receptor function through distinct sites

1 reference

12 December 2020

Brain and plasma cations and experimental seizures in normal and desoxycorticosterone-treated rats.

1 reference

12 December 2020

Arcaine blocks N-methyl-D-aspartate receptor responses by an open channel mechanism: whole-cell and single-channel recording studies in cultured hippocampal neurons.

1 reference

12 December 2020

Modification of seizure activity by electrical stimulation. II. Motor seizure

1 reference

12 December 2020

Role of AMPA and GluR5 kainate receptors in the development and expression of amygdala kindling in the mouse

1 reference

12 December 2020

Quantification of neurosteroids in rat plasma and brain following swim stress and allopregnanolone administration using negative chemical ionization gas chromatography/mass spectrometry

1 reference

12 December 2020

Mineralocorticoid receptors mediate the enhancing effects of corticosterone on convulsion susceptibility in mice.

1 reference

12 December 2020

Progesterone withdrawal decreases latency to and increases duration of electrified prod burial: a possible rat model of PMS anxiety.

1 reference

12 December 2020

Four-amino acid segment in steroid 5 alpha-reductase 1 confers sensitivity to finasteride, a competitive inhibitor

1 reference

12 December 2020

Characterization of the anticonvulsant properties of ganaxolone (CCD 1042; 3alpha-hydroxy-3beta-methyl-5alpha-pregnan-20-one), a selective, high-affinity, steroid modulator of the gamma-aminobutyric acid(A) receptor

1 reference

12 December 2020

Steroid modulation of the GABAA receptor complex: electrophysiological studies.

1 reference

12 December 2020

Neurosteroids: expression of steroidogenic enzymes and regulation of steroid biosynthesis in the central nervous system.

1 reference

12 December 2020

Indomethacin inhibits lordosis induced by ring A-reduced progestins: possible role of 3alpha-oxoreduction in progestin-facilitated lordosis

1 reference

12 December 2020

Anticonvulsant drugs and their antagonism of kindled amygdaloid seizures in rats

1 reference

12 December 2020

Anxiolytic activity of an endogenous adrenal steroid

1 reference

12 December 2020

Comparative study of the anticonvulsant effect of gamma-aminobutyric acid agonists in the feline kindling model of epilepsy

1 reference

12 December 2020

Decreased convulsant potency of picrotoxin and pentetrazol and enhanced [3H]flunitrazepam cortical binding following stressful manipulations in rats

1 reference

12 December 2020

Social isolation-induced decreases in both the abundance of neuroactive steroids and GABA(A) receptor function in rat brain

1 reference

12 December 2020

Stress as a risk factor for seizures among adults with epilepsy.

1 reference

12 December 2020

Effects of water immersion stress on convulsions induced by pentylenetetrazol

1 reference

12 December 2020

Identity of emotional triggers in epilepsy

1 reference

12 December 2020

Stimulation and suppression of the mineralocorticoid hormones in normal subjects and adrenocortical disorders.

1 reference

12 December 2020

10.1523/JNEUROSCI.22-09-03795.2002

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11978855%20AND%20SRC:MED&resulttype=core&format=json

10 December 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11978855%20AND%20SRC:MED&resulttype=core&format=json

10 December 2019

PubMed publication ID

11978855

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11978855%20AND%20SRC:MED&resulttype=core&format=json