(Q34035802)

30 July 2017

title

Comparing HIV-1 and HIV-2 infection: Lessons for viral immunopathogenesis (English)

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30 July 2017

Derek C Macallan

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Sarah Rowland-Jones

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30 July 2017

Assan Jaye

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30 July 2017

Samuel Nyamweya

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30 July 2017

Andrea Hegedus

series ordinal

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30 July 2017

Katie L Flanagan

series ordinal

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30 July 2017

publication date

26 February 2013

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Reviews in Medical Virology

30 July 2017

published in

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30 July 2017

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30 July 2017

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30 July 2017

page(s)

221-240

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Origins of HIV and the AIDS pandemic

30 July 2017

cites work

1 reference

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21 January 2018

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Novel agents for the treatment of HIV-2 infection

21 January 2018

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Population migration and the spread of types 1 and 2 human immunodeficiency viruses

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Twenty years of prospective molecular epidemiology in Senegal: changes in HIV diversity

21 January 2018

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Sixteen years of HIV surveillance in a West African research clinic reveals divergent epidemic trends of HIV-1 and HIV-2.

21 January 2018

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Regional differences in HIV trends in The Gambia: results from sentinel surveillance among pregnant women

21 January 2018

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Lower levels of HIV RNA in semen in HIV-2 compared with HIV-1 infection: implications for differences in transmission

21 January 2018

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Changes in prevalence and incidence of HIV-1, HIV-2 and dual infections in urban areas of Bissau, Guinea-Bissau: is HIV-2 disappearing?

21 January 2018

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Assessment of mother-to-child HIV-1 and HIV-2 transmission: an AIDS reference laboratory collaborative study.

21 January 2018

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21 January 2018

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Is HIV-2- induced AIDS different from HIV-1-associated AIDS? Data from a West African clinic

21 January 2018

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AIDS caused by HIV1 and HIV2 infection: are there clinical differences? Results of AIDS surveillance 1986-97 at Fann Hospital in Dakar, Senegal

21 January 2018

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Cerebrospinal fluid viral load, virus isolation, and intrathecal immunoactivation in HIV type 2 infection

21 January 2018

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HIV type 2 demyelinating encephalomyelitis

21 January 2018

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Identification of a subset of human immunodeficiency virus type 1 (HIV-1), HIV-2, and simian immunodeficiency virus strains able to exploit an alternative coreceptor on untransformed human brain and lymphoid cells

21 January 2018

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Productive HIV-2 infection in the brain is restricted to macrophages/microglia

21 January 2018

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Cytokines and growth factors in the pathogenesis of AIDS-associated Kaposi's sarcoma

21 January 2018

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9-year HIV-2-associated mortality in an urban community in Bissau, west Africa

21 January 2018

1 reference

Equal plasma viral loads predict a similar rate of CD4+ T cell decline in human immunodeficiency virus (HIV) type 1- and HIV-2-infected individuals from Senegal, West Africa

21 January 2018

1 reference

Cell-associated viral burden provides evidence of ongoing viral replication in aviremic HIV-2-infected patients

21 January 2018

1 reference

Proviral load and immune function in blood and lymph node during HIV-1 and HIV-2 infection

21 January 2018

1 reference

Mortality of HIV-1, HIV-2 and HIV-1/HIV-2 dually infected patients in a clinic-based cohort in The Gambia

21 January 2018

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Undetectable plasma viral load predicts normal survival in HIV-2-infected people in a West African village

21 January 2018

1 reference

Immunological predictors of survival in HIV type 2-infected rural villagers in Guinea-Bissau

21 January 2018

1 reference

Are plasma biomarkers of immune activation predictive of HIV progression: a longitudinal comparison and analyses in HIV-1 and HIV-2 infections?

21 January 2018

1 reference

Cause of death among people with retroviral infection in rural Guinea-Bissau.

21 January 2018

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Survival of HIV-1 and HIV-2 perinatally infected children in The Gambia

21 January 2018

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Clinical and laboratory predictors of survival in Gambian patients with symptomatic HIV-1 or HIV-2 infection

21 January 2018

1 reference

Mortality and immunovirological outcomes on antiretroviral therapy in HIV-1 and HIV-2-infected individuals in the Gambia

21 January 2018

1 reference

Genome organization and transactivation of the human immunodeficiency virus type 2.

21 January 2018

1 reference

Cytopathicity of human immunodeficiency virus type 2 (HIV-2) in human lymphoid tissue is coreceptor dependent and comparable to that of HIV-1

21 January 2018

1 reference

Low plasma human immunodeficiency virus type 2 viral load is independent of proviral load: low virus production in vivo

21 January 2018

1 reference

Evolution of human immunodeficiency virus type 2 coreceptor usage, autologous neutralization, envelope sequence and glycosylation

21 January 2018

1 reference

HIV-2 genetic evolution in patients with advanced disease is faster than that in matched HIV-1 patients

21 January 2018

1 reference

Evidence for negative selective pressure in HIV-2 evolution in vivo

21 January 2018

1 reference

Potent autologous and heterologous neutralizing antibody responses occur in HIV-2 infection across a broad range of infection outcomes

21 January 2018

1 reference

The replicative fitness of primary human immunodeficiency virus type 1 (HIV-1) group M, HIV-1 group O, and HIV-2 isolates

21 January 2018

1 reference

Human immunodeficiency virus types 1 and 2 have different replication kinetics in human primary macrophage culture.

21 January 2018

1 reference

CCR5 receptor expression is down-regulated in HIV type 2 infection: implication for viral control and protection

21 January 2018

1 reference

Efficient thymopoiesis contributes to the maintenance of peripheral CD4 T cells during chronic human immunodeficiency virus type 2 infection

21 January 2018

1 reference

Maintenance of HIV-specific CD4+ T cell help distinguishes HIV-2 from HIV-1 infection.

21 January 2018

1 reference

Polyfunctional T cell responses are a hallmark of HIV-2 infection

21 January 2018

1 reference

Comprehensive analysis of HIV Gag-specific IFN-gamma response in HIV-1- and HIV-2-infected asymptomatic patients from a clinical cohort in The Gambia

21 January 2018

1 reference

Comparison of human immunodeficiency virus (HIV)-specific T-cell responses in HIV-1- and HIV-2-infected individuals in Senegal.

21 January 2018

1 reference

Distinct profile of T cell activation in HIV type 2 compared to HIV type 1 infection: differential mechanism for immunoprotection.

21 January 2018

1 reference

Greater CD8+ TCR heterogeneity and functional flexibility in HIV-2 compared to HIV-1 infection

21 January 2018

1 reference

Robust Gag-specific T cell responses characterize viremia control in HIV-2 infection

21 January 2018

1 reference

Comparison of the frequency of interleukin (IL)-2-, interferon-gamma-, and IL-4-producing T cells in 2 diseases, human immunodeficiency virus types 1 and 2, with distinct clinical outcomes.

21 January 2018

1 reference

No differences in cellular immune responses between asymptomatic HIV type 1- and type 2-infected Gambian patients

21 January 2018

1 reference

Gag-specific CD4+ T-cell frequency is inversely correlated with proviral load and directly correlated with immune activation in infection with human immunodeficiency virus type 2 (HIV-2) but not HIV-1.

21 January 2018

1 reference

Virologic and immunologic characterization of long-term survivors of human immunodeficiency virus type 1 infection

21 January 2018

1 reference

Neutralizing antibody responses to human immunodeficiency virus type 1 in primary infection and long-term-nonprogressive infection

21 January 2018

1 reference

Antibody neutralization and escape by HIV-1

21 January 2018

1 reference

Potent intratype neutralizing activity distinguishes human immunodeficiency virus type 2 (HIV-2) from HIV-1

21 January 2018

1 reference

Comparison of heterologous neutralizing antibody responses of human immunodeficiency virus type 1 (HIV-1)- and HIV-2-infected Senegalese patients: distinct patterns of breadth and magnitude distinguish HIV-1 and HIV-2 infections

21 January 2018

1 reference

Broad and potent neutralizing antibody responses elicited in natural HIV-2 infection

21 January 2018

1 reference

Natural killer cell function is well preserved in asymptomatic human immunodeficiency virus type 2 (HIV-2) infection but similar to that of HIV-1 infection when CD4 T-cell counts fall.

21 January 2018

1 reference

Differential restriction of human immunodeficiency virus type 2 and simian immunodeficiency virus SIVmac by TRIM5alpha alleles

21 January 2018

1 reference

HIV-2 capsids distinguish high and low virus load patients in a West African community cohort

21 January 2018

1 reference

Species-specific activity of SIV Nef and HIV-1 Vpu in overcoming restriction by tetherin/BST2

21 January 2018

1 reference

Antagonism to and intracellular sequestration of human tetherin by the human immunodeficiency virus type 2 envelope glycoprotein

21 January 2018

1 reference

HIV/simian immunodeficiency virus (SIV) accessory virulence factor Vpx loads the host cell restriction factor SAMHD1 onto the E3 ubiquitin ligase complex CRL4DCAF1.

21 January 2018

1 reference

SAMHD1 is the dendritic- and myeloid-cell-specific HIV-1 restriction factor counteracted by Vpx

21 January 2018

1 reference

Vpx relieves inhibition of HIV-1 infection of macrophages mediated by the SAMHD1 protein

21 January 2018

1 reference

A cryptic sensor for HIV-1 activates antiviral innate immunity in dendritic cells

21 January 2018

1 reference

Dendritic cells are less susceptible to human immunodeficiency virus type 2 (HIV-2) infection than to HIV-1 infection

21 January 2018

1 reference

A specific region of 37 amino acid residues in the SPRY (B30.2) domain of African green monkey TRIM5alpha determines species-specific restriction of simian immunodeficiency virus SIVmac infection

21 January 2018

1 reference

Studies on toll-like receptor stimuli responsiveness in HIV-1 and HIV-2 infections

21 January 2018

1 reference

Shorter survival in advanced human immunodeficiency virus type 1 infection is more closely associated with T lymphocyte activation than with plasma virus burden or virus chemokine coreceptor usage.

21 January 2018

1 reference

Direct relationship between virus load and systemic immune activation in HIV-2 infection

21 January 2018

1 reference

Downregulation of the T-cell receptor by human immunodeficiency virus type 2 Nef does not protect against disease progression

21 January 2018

1 reference

Directly measured kinetics of circulating T lymphocytes in normal and HIV-1-infected humans

21 January 2018

1 reference

Increased turnover of T lymphocytes in HIV-1 infection and its reduction by antiretroviral therapy

21 January 2018

1 reference

Reduced immune activation and T cell apoptosis in human immunodeficiency virus type 2 compared with type 1: correlation of T cell apoptosis with beta2 microglobulin concentration and disease evolution

21 January 2018

1 reference

HIV type 2 primary isolates induce a lower degree of apoptosis "in vitro" compared with HIV type 1 primary isolates

21 January 2018

1 reference

Analysis of lymphocyte cell death and apoptosis in HIV-2-infected patients.

21 January 2018

1 reference

Efficient Nef-mediated downmodulation of TCR-CD3 and CD28 is associated with high CD4+ T cell counts in viremic HIV-2 infection

21 January 2018

1 reference

PD-1 and its ligand PD-L1 are progressively up-regulated on CD4 and CD8 T-cells in HIV-2 infection irrespective of the presence of viremia.

21 January 2018

1 reference

Low level viremia and high CD4% predict normal survival in a cohort of HIV type-2-infected villagers

21 January 2018

1 reference

Differences in proviral DNA load between HIV-1- and HIV-2-infected patients

21 January 2018

1 reference

In vitro replication capacity of HIV-2 variants from long-term aviremic individuals

21 January 2018

1 reference

Highly avid, oligoclonal, early-differentiated antigen-specific CD8+ T cells in chronic HIV-2 infection

21 January 2018

1 reference

Microbial Translocation Correlates with the Severity of Both HIV‐1 and HIV‐2 Infections

21 January 2018

1 reference

HIV Interplay with SAMHD1

21 January 2018

1 reference

21 January 2018

Identifiers

DOI

10.1002/RMV.1739

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30 July 2017

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