(Q34018172)

30 July 2017

title

Protein-free small nuclear RNAs catalyze a two-step splicing reaction (English)

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30 July 2017

Sarah Geisler

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Saba Valadkhan

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30 July 2017

Afshin Mohammadi

series ordinal

1 reference

30 July 2017

Yasaman Jaladat

series ordinal

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30 July 2017

language of work or name

English

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publication date

22 June 2009

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Proceedings of the National Academy of Sciences of the United States of America

30 July 2017

published in

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30 July 2017

volume

106

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30 July 2017

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30 July 2017

page(s)

11901-11906

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Toward predicting self-splicing and protein-facilitated splicing of group I introns

30 July 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2715495

Crystal Structure of a Self-Spliced Group II Intron

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2715495

Protein-free spliceosomal snRNAs catalyze a reaction that resembles the first step of splicing

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2715495

The spliceosome: caught in a web of shifting interactions

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2715495

The spliceosome: a ribozyme at heart?

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2715495

Prp8 protein: at the heart of the spliceosome

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2715495

Roles of protein subunits in RNA-protein complexes: lessons from ribonuclease P.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2715495

The spliceosome: the most complex macromolecular machine in the cell?

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2715495

Group II introns: structure and catalytic versatility of large natural ribozymes

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2715495

Characterization of the catalytic activity of U2 and U6 snRNAs

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2715495

The question remains: is the spliceosome a ribozyme?

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2715495

A tertiary interaction detected in a human U2-U6 snRNA complex assembled in vitro resembles a genetically proven interaction in yeast

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2715495

Metal ion catalysis during the exon-ligation step of nuclear pre-mRNA splicing: extending the parallels between the spliceosome and group II introns

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2715495

Mechanical devices of the spliceosome: motors, clocks, springs, and things

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2715495

Randomization-selection analysis of snRNAs in vivo: evidence for a tertiary interaction in the spliceosome

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2715495

Heterogeneous Nuclear RNA Promotes Synthesis of (2′,5′)Oligoadenylate and Is Cleaved by the (2′,5′)Oligoadenylate-Activated Endoribonuclease

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2715495

Efficient trans-splicing of a yeast mitochondrial RNA group II intron implicates a strong 5' exon-intron interaction.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2715495

The generality of self-splicing RNA: relationship to nuclear mRNA splicing

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2715495

On the origin of RNA splicing and introns

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2715495

Evidence for a base-pairing interaction between U6 small nuclear RNA and 5' splice site during the splicing reaction in yeast

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2715495

Association of U6 snRNA with the 5'-splice site region of pre-mRNA in the spliceosome

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2715495

Repositioning of the reaction intermediate within the catalytic center of the spliceosome.

5 July 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0902020106

Proximity of conserved U6 and U2 snRNA elements to the 5' splice site region in activated spliceosomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0902020106

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0902020106

Is the spliceosome a ribonucleoprotein enzyme?

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0902020106

More than one way to splice an RNA: branching without a bulge and splicing without branching in group II introns.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0902020106

Metal-ion coordination by U6 small nuclear RNA contributes to catalysis in the spliceosome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0902020106

U2–U6 RNA folding reveals a group II intron-like domain and a four-helix junction

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0902020106

Group II intron splicing in vivo by first-step hydrolysis

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2715495

Metal ion catalysis during splicing of premessenger RNA

29 October 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0902020106

Group II intron self-splicing. Alternative reaction conditions yield novel products

21 January 2018

1 reference

12 December 2020

Interactions of small nuclear RNA's with precursor messenger RNA during in vitro splicing

1 reference

12 December 2020

The U5 and U6 small nuclear RNAs as active site components of the spliceosome

1 reference

12 December 2020

Involvement of U6 snRNA in 5' splice site selection

1 reference

12 December 2020

Both catalytic steps of nuclear pre-mRNA splicing are reversible

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.0902020106

1 reference

30 July 2017

0 references

1 reference

30 July 2017

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