(Q33966313)

30 July 2017

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title

Role of TNF in lymphocyte-mediated cytotoxicity (English)

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30 July 2017

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Smyth MJ

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30 July 2017

Johnstone RW

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30 July 2017

publication date

1 August 2000

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Microscopy Research and Technique

30 July 2017

published in

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30 July 2017

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30 July 2017

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30 July 2017

page(s)

196-208

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Tumor necrosis factor receptor-associated factors (TRAFs)--a family of adapter proteins that regulates life and death

30 July 2017

cites work

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Crystal structure of the soluble human 55 kd TNF receptor-human TNF beta complex: implications for TNF receptor activation

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21 January 2018

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Involvement of MACH, a novel MORT1/FADD-interacting protease, in Fas/APO-1- and TNF receptor-induced cell death

21 January 2018

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FADD, a novel death domain-containing protein, interacts with the death domain of Fas and initiates apoptosis

21 January 2018

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FADD/MORT1 is a common mediator of CD95 (Fas/APO-1) and tumor necrosis factor receptor-induced apoptosis

21 January 2018

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Suppression of tumor necrosis factor-induced cell death by inhibitor of apoptosis c-IAP2 is under NF-kappaB control

21 January 2018

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Lpr and gld: single gene models of systemic autoimmunity and lymphoproliferative disease

21 January 2018

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IAP family proteins--suppressors of apoptosis

21 January 2018

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An ovalbumin peptide-specific cytotoxic T cell clone with antigen self-presentation capacity uses two distinct mechanisms to kill target cells

21 January 2018

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RAIDD is a new 'death' adaptor molecule

21 January 2018

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Decreased sensitivity to tumour-necrosis factor but normal T-cell development in TNF receptor-2-deficient mice

21 January 2018

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CASH, a novel caspase homologue with death effector domains

21 January 2018

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Virus proteins that counteract host immune defenses

21 January 2018

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Direct evidence for tumor necrosis factor-induced mitochondrial reactive oxygen intermediates and their involvement in cytotoxicity

21 January 2018

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Reactive oxygen species- and dimerization-induced activation of apoptosis signal-regulating kinase 1 in tumor necrosis factor-alpha signal transduction

21 January 2018

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The transmembrane form of tumor necrosis factor is the prime activating ligand of the 80 kDa tumor necrosis factor receptor

21 January 2018

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Induction of cell death by tumour necrosis factor (TNF) receptor 2, CD40 and CD30: a role for TNF-R1 activation by endogenous membrane-anchored TNF.

21 January 2018

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Cytotoxic T lymphocytes inhibit hepatitis B virus gene expression by a noncytolytic mechanism in transgenic mice

21 January 2018

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Phenotypic and functional separation of memory and effector human CD8+ T cells

21 January 2018

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Dual regulation of caspase activity by hydrogen peroxide: implications for apoptosis

21 January 2018

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Anti-apoptotic potential of insect cellular and viral IAPs in mammalian cells.

21 January 2018

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The p70 tumor necrosis factor receptor mediates cytotoxicity

21 January 2018

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Tumor necrosis factor receptor-mediated signaling pathways

21 January 2018

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A novel function of CD40: induction of cell death in transformed cells

21 January 2018

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The TNF receptor 1-associated protein TRADD signals cell death and NF-kappa B activation

21 January 2018

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TNF-dependent recruitment of the protein kinase RIP to the TNF receptor-1 signaling complex

21 January 2018

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NMR structure and mutagenesis of the Fas (APO-1/CD95) death domain

21 January 2018

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Inhibition of death receptor signals by cellular FLIP

21 January 2018

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Cytotoxicity mediated by T cells and natural killer cells is greatly impaired in perforin-deficient mice

21 January 2018

1 reference

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Fas and perforin pathways as major mechanisms of T cell-mediated cytotoxicity

21 January 2018

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The death domain kinase RIP mediates the TNF-induced NF-kappaB signal

21 January 2018

1 reference

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Vaccinia virus serpin B13R (SPI-2) inhibits interleukin-1beta-converting enzyme and protects virus-infected cells from TNF- and Fas-mediated apoptosis, but does not prevent IL-1beta-induced fever

21 January 2018

1 reference

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A novel addition to the T cell repertory. Cell surface expression of tumor necrosis factor/cachectin by activated normal human T cells

21 January 2018

1 reference

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Tumor necrosis factor sustains the generalized lymphoproliferative disorder (gld) phenotype

21 January 2018

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Inhibition of tumor necrosis factor and interferon triggered responses by DNA viruses

21 January 2018

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Tumor necrosis factor-alpha and interleukin 6 synergistically induce T cell growth

21 January 2018

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T cell receptor-dependent cell death of T cell hybridomas mediated by the CD30 cytoplasmic domain in association with tumor necrosis factor receptor-associated factors

21 January 2018

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Differentiation of follicular dendritic cells and full antibody responses require tumor necrosis factor receptor-1 signaling

21 January 2018

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Cleavage of BID by caspase 8 mediates the mitochondrial damage in the Fas pathway of apoptosis

21 January 2018

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Perforin-independent CD8(+) T-cell-mediated cytotoxicity of alveolar epithelial cells is preferentially mediated by tumor necrosis factor-alpha: relative insensitivity to Fas ligand

21 January 2018

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Dissection of TNF receptor 1 effector functions: JNK activation is not linked to apoptosis while NF-kappaB activation prevents cell death

21 January 2018

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Molecular cloning and expression of the human 55 kd tumor necrosis factor receptor

21 January 2018

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Bid, a Bcl2 interacting protein, mediates cytochrome c release from mitochondria in response to activation of cell surface death receptors

21 January 2018

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21 January 2018

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Tumor necrosis factor-induced apoptosis is mediated by a CrmA-sensitive cell death pathway

21 January 2018

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Membrane form of TNF alpha induces both cell lysis and apoptosis in susceptible target cells

21 January 2018

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FLICE, a novel FADD-homologous ICE/CED-3-like protease, is recruited to the CD95 (Fas/APO-1) death--inducing signaling complex

21 January 2018

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21 January 2018

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Apoptosis by death factor

21 January 2018

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Tumor necrosis factor (TNF).

21 January 2018

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Immune and inflammatory responses in TNF alpha-deficient mice: a critical requirement for TNF alpha in the formation of primary B cell follicles, follicular dendritic cell networks and germinal centers, and in the maturation of the humoral immune re

21 January 2018

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Peyer's patch organogenesis is intact yet formation of B lymphocyte follicles is defective in peripheral lymphoid organs of mice deficient for tumor necrosis factor and its 55-kDa receptor

21 January 2018

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A nonsecretable cell surface mutant of tumor necrosis factor (TNF) kills by cell-to-cell contact

21 January 2018

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Mice deficient for the 55 kd tumor necrosis factor receptor are resistant to endotoxic shock, yet succumb to L. monocytogenes infection

21 January 2018

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The CD95 (APO-1/Fas) receptor activates NF-kappaB independently of its cytotoxic function

21 January 2018

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Inhibition of cytotoxic T cell development by transforming growth factor beta and reversal by recombinant tumor necrosis factor alpha

21 January 2018

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Identification and characterization of an IkappaB kinase

21 January 2018

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Tumor necrosis factor alpha-induced activation of c-jun N-terminal kinase is mediated by TRAF2.

21 January 2018

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Mice lacking the tumour necrosis factor receptor 1 are resistant to TNF-mediated toxicity but highly susceptible to infection by Listeria monocytogenes

21 January 2018

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The TNFR2-TRAF signaling complex contains two novel proteins related to baculoviral inhibitor of apoptosis proteins

21 January 2018

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Regulation of tumor necrosis factor (TNF)-alpha synthesis and TNF receptors expression in T lymphocytes through the CD2 activation pathway

21 January 2018

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The interaction of p62 with RIP links the atypical PKCs to NF-kappaB activation

21 January 2018

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CD28-independent, TRAF2-dependent costimulation of resting T cells by 4-1BB ligand

21 January 2018

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Molecular cloning and expression of a receptor for human tumor necrosis factor

21 January 2018

1 reference

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Conversion of membrane-bound Fas(CD95) ligand to its soluble form is associated with downregulation of its proapoptotic activity and loss of liver toxicity

21 January 2018

1 reference

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Challenging cytokine redundancy: inflammatory cell movement and clinical course of experimental autoimmune encephalomyelitis are normal in lymphotoxin-deficient, but not tumor necrosis factor-deficient, mice

21 January 2018

1 reference

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Monoclonal antibodies specific for murine p55 and p75 tumor necrosis factor receptors: identification of a novel in vivo role for p75

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1097-0029%2820000801%2950%3A3%3C196%3A%3AAID-JEMT3%3E3.0.CO%3B2-9

Casper is a FADD- and caspase-related inducer of apoptosis

21 January 2018

1 reference

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Tumor necrosis factor (TNF)-mediated kinase cascades: bifurcation of nuclear factor-kappaB and c-jun N-terminal kinase (JNK/SAPK) pathways at TNF receptor-associated factor 2

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1097-0029%2820000801%2950%3A3%3C196%3A%3AAID-JEMT3%3E3.0.CO%3B2-9

Conversion of HPV 18 positive non-tumorigenic HeLa-fibroblast hybrids to invasive growth involves loss of TNF-alpha mediated repression of viral transcription and modification of the AP-1 transcription complex.

21 January 2018

1 reference

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RIP: a novel protein containing a death domain that interacts with Fas/APO-1 (CD95) in yeast and causes cell death

21 January 2018

1 reference

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JNK is involved in signal integration during costimulation of T lymphocytes.

21 January 2018

1 reference

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The roles of Fas/APO-1 (CD95) and TNF in antigen-induced programmed cell death in T cell receptor transgenic mice.

21 January 2018

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The regulation of reactive oxygen species production during programmed cell death

21 January 2018

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The two different receptors for tumor necrosis factor mediate distinct cellular responses

21 January 2018

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Tumor necrosis factor's cytotoxic activity is signaled by the p55 TNF receptor

21 January 2018

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Fas- and tumor necrosis factor-induced apoptosis is inhibited by the poxvirus crmA gene product

21 January 2018

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Cloning and expression of apoptosis inhibitory protein homologs that function to inhibit apoptosis and/or bind tumor necrosis factor receptor-associated factors

21 January 2018

1 reference

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Inhibition of TNF-induced apoptosis by NF-kappa B.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1097-0029%2820000801%2950%3A3%3C196%3A%3AAID-JEMT3%3E3.0.CO%3B2-9

Perforin dependence of natural killer cell-mediated tumor control in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1097-0029%2820000801%2950%3A3%3C196%3A%3AAID-JEMT3%3E3.0.CO%3B2-9

Inhibition of caspases increases the sensitivity of L929 cells to necrosis mediated by tumor necrosis factor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1097-0029%2820000801%2950%3A3%3C196%3A%3AAID-JEMT3%3E3.0.CO%3B2-9

Manganous superoxide dismutase is essential for cellular resistance to cytotoxicity of tumor necrosis factor

21 January 2018

1 reference

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Daxx, a Novel Fas-Binding Protein That Activates JNK and Apoptosis

21 January 2018

1 reference

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T cell receptor (TCR) engagement leads to activation-induced splicing of tumor necrosis factor (TNF) nuclear pre-mRNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1097-0029%2820000801%2950%3A3%3C196%3A%3AAID-JEMT3%3E3.0.CO%3B2-9

Natural killer (NK) cell-mediated cytotoxicity: differential use of TRAIL and Fas ligand by immature and mature primary human NK cells

21 January 2018

1 reference

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Induction of apoptosis in mature T cells by tumour necrosis factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1097-0029%2820000801%2950%3A3%3C196%3A%3AAID-JEMT3%3E3.0.CO%3B2-9

Differential TCR Signaling Regulates Apoptosis and Immunopathology during Antigen Responses In Vivo

21 January 2018

1 reference

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Reactive Oxygen Species Regulate Activation-Induced T Cell Apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1097-0029%2820000801%2950%3A3%3C196%3A%3AAID-JEMT3%3E3.0.CO%3B2-9

REGULATION OF APO-2 LIGAND/TRAIL EXPRESSION IN NK CELLS—INVOLVEMENT IN NK CELL-MEDIATED CYTOTOXICITY

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1097-0029%2820000801%2950%3A3%3C196%3A%3AAID-JEMT3%3E3.0.CO%3B2-9

Failure of TGF beta1 and IL-12 to regulate human FasL and mTNF alloreactive cytotoxic T-cell pathways

21 January 2018

1 reference

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TNF in Pathophysiology: Biosynthetic Regulation

21 January 2018

1 reference

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Unraveling function in the TNF ligand and receptor families

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1097-0029%2820000801%2950%3A3%3C196%3A%3AAID-JEMT3%3E3.0.CO%3B2-9

Mitochondrial perturbations define lymphocytes undergoing apoptotic depletion in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1097-0029%2820000801%2950%3A3%3C196%3A%3AAID-JEMT3%3E3.0.CO%3B2-9

Tumor necrosis factor (TNF) receptor type 2 mediates thymocyte proliferation independently of TNF receptor type 1

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1097-0029%2820000801%2950%3A3%3C196%3A%3AAID-JEMT3%3E3.0.CO%3B2-9

Continuous autotropic signaling by membrane-expressed tumor necrosis factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1097-0029%2820000801%2950%3A3%3C196%3A%3AAID-JEMT3%3E3.0.CO%3B2-9

A novel family of viral death effector domain-containing molecules that inhibit both CD-95- and tumor necrosis factor receptor-1-induced apoptosis

21 January 2018

1 reference

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Induction of interleukin-2 receptor by tumor necrosis factor alpha on cultured ovarian tumor-associated lymphocytes

21 January 2018

1 reference

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Cytotoxic pathways in the skin allograft rejection by CD4+ T cells

21 January 2018

1 reference

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TRAF2 is essential for JNK but not NF-kappaB activation and regulates lymphocyte proliferation and survival

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1097-0029%2820000801%2950%3A3%3C196%3A%3AAID-JEMT3%3E3.0.CO%3B2-9

LFA-3 co-stimulates cytokine secretion by cytotoxic T lymphocytes by providing a TCR-independent activation signal

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1097-0029%2820000801%2950%3A3%3C196%3A%3AAID-JEMT3%3E3.0.CO%3B2-9

Involvement of APO2 ligand/TRAIL in activation-induced death of Jurkat and human peripheral blood T cells

21 January 2018

1 reference

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An essential role for ectodomain shedding in mammalian development

21 January 2018

1 reference

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Effects of interferon-gamma and tumour necrosis factor-alpha on the development of cytotoxic T lymphocytes in autologous mixed lymphocyte tumour cultures with human melanoma

21 January 2018

1 reference

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The fas antigen is involved in peripheral but not thymic deletion of T lymphocytes in T cell receptor transgenic mice

21 January 2018

1 reference

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Delayed kinetics of tumor necrosis factor-mediated bystander lysis by peptide-specific CD8+ cytotoxic T lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1097-0029%2820000801%2950%3A3%3C196%3A%3AAID-JEMT3%3E3.0.CO%3B2-9

Tumor necrosis factor receptor p55 mediates deletion of peripheral cytotoxic T lymphocytesin vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1097-0029%2820000801%2950%3A3%3C196%3A%3AAID-JEMT3%3E3.0.CO%3B2-9

Fas ligand in human serum

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1097-0029%2820000801%2950%3A3%3C196%3A%3AAID-JEMT3%3E3.0.CO%3B2-9

Inhibition of fas death signals by FLIPs

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1097-0029%2820000801%2950%3A3%3C196%3A%3AAID-JEMT3%3E3.0.CO%3B2-9

10.1002/1097-0029(20000801)50:3<196::AID-JEMT3>3.0.CO;2-9

21 January 2018

Identifiers

DOI

1 reference

30 July 2017

1 reference