(Q33965673)

30 July 2017

title

Increased adipocyte O2 consumption triggers HIF-1α, causing inflammation and insulin resistance in obesity. (English)

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30 July 2017

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Yun Sok Lee

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Jung-whan Kim

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Simon Schenk

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Anne Murphy

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Randall S Johnson

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Jerrold M Olefsky

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30 July 2017

Olivia Osborne

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30 July 2017

Da Young Oh

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30 July 2017

Roman Sasik

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30 July 2017

Ai Chen

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30 July 2017

Heekyung Chung

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30 July 2017

Steven M Watkins

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30 July 2017

Oswald Quehenberger

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30 July 2017

language of work or name

English

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publication date

1 June 2014

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30 July 2017

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30 July 2017

volume

157

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30 July 2017

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30 July 2017

page(s)

1339-1352

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describes a project that uses

30 July 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4114226/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

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5 July 2018

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5 July 2018

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5 July 2018

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Selective inhibition of hypoxia-inducible factor 1α ameliorates adipose tissue dysfunction.

5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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Inflammation is necessary for long-term but not short-term high-fat diet-induced insulin resistance

5 July 2018

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Disruption of hypoxia-inducible factor 1 in adipocytes improves insulin sensitivity and decreases adiposity in high-fat diet-fed mice

5 July 2018

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Deficiency of the leukotriene B4 receptor, BLT-1, protects against systemic insulin resistance in diet-induced obesity

5 July 2018

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Desnutrin/ATGL is regulated by AMPK and is required for a brown adipose phenotype

5 July 2018

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Cellular hypoxia of pancreatic beta-cells due to high levels of oxygen consumption for insulin secretion in vitro

5 July 2018

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Kdo2-Lipid A, a TLR4-specific Agonist, Induces de Novo Sphingolipid Biosynthesis in RAW264.7 Macrophages, Which Is Essential for Induction of Autophagy

5 July 2018

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Adipose tissue-specific inhibition of hypoxia-inducible factor 1{alpha} induces obesity and glucose intolerance by impeding energy expenditure in mice

5 July 2018

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5 July 2018

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Hypoxia-mediated expression of 5-lipoxygenase-activating protein involves HIF-1alpha and NF-kappaB and microRNAs 135a and 199a-5p

5 July 2018

1 reference

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Differential activation and antagonistic function of HIF-{alpha} isoforms in macrophages are essential for NO homeostasis

5 July 2018

1 reference

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5 July 2018

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Reduced adipose tissue oxygenation in human obesity: evidence for rarefaction, macrophage chemotaxis, and inflammation without an angiogenic response

5 July 2018

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A stress signaling pathway in adipose tissue regulates hepatic insulin resistance

5 July 2018

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Adipose-specific knockout of raptor results in lean mice with enhanced mitochondrial respiration

5 July 2018

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Dysregulation of adipose glutathione peroxidase 3 in obesity contributes to local and systemic oxidative stress

5 July 2018

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O(2)-sensing signal cascade: clamping of O(2) respiration, reduced ATP utilization, and inducible fumarate respiration

5 July 2018

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Adipose tissue hypoxia in obesity and its impact on adipocytokine dysregulation

5 July 2018

1 reference

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Inhibition of mitochondrial respiration elevates oxygen concentration but leaves regulation of hypoxia-inducible factor (HIF) intact

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4114226

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5 July 2018

1 reference

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5 July 2018

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Redistribution of intracellular oxygen in hypoxia by nitric oxide: effect on HIF1alpha

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4114226

Adipose-specific peroxisome proliferator-activated receptor gamma knockout causes insulin resistance in fat and liver but not in muscle

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4114226

Effects of peroxisome proliferator-activated receptor delta on placentation, adiposity, and colorectal cancer

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4114226

Regulation of inducible nitric oxide synthase expression in IFN-gamma-treated murine macrophages cultured under hypoxic conditions.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4114226

Alterations in adipocyte free fatty acid re-esterification associated with obesity and weight reduction in man.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4114226

Hypoxia-inducible factor 1alpha induces fibrosis and insulin resistance in white adipose tissue.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4114226

Targeted disruption of inducible nitric oxide synthase protects against obesity-linked insulin resistance in muscle

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4114226

Carboxyatractylate inhibits the uncoupling effect of free fatty acids

29 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24906151

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1016/J.CELL.2014.05.012

1 reference

30 July 2017

1 reference

30 July 2017

1 reference