(Q33942765)

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Stimulation of beta-amyloid precursor protein trafficking by insulin reduces intraneuronal beta-amyloid and requires mitogen-activated protein kinase signaling.

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Europe PubMed Central

PubMed publication ID

30 July 2017

Stimulation of beta-amyloid precursor protein trafficking by insulin reduces intraneuronal beta-amyloid and requires mitogen-activated protein kinase signaling (English)

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Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6762523&resulttype=core&format=json

12 May 2020

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Laura Gasparini

1

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6762523&resulttype=core&format=json

12 May 2020

4

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6762523&resulttype=core&format=json

12 May 2020

6

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P Greengard

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6762523&resulttype=core&format=json

12 May 2020

5

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M F Beal

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6762523&resulttype=core&format=json

12 May 2020

author name string

G K Gouras

2

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6762523&resulttype=core&format=json

12 May 2020

R Wang

3

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6762523&resulttype=core&format=json

12 May 2020

H Xu

7

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6762523&resulttype=core&format=json

12 May 2020

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publication date

1 April 2001

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Europe PubMed Central

PubMed publication ID

30 July 2017

Journal of Neuroscience

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Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6762523&resulttype=core&format=json

12 May 2020

21

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Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6762523&resulttype=core&format=json

12 May 2020

8

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6762523&resulttype=core&format=json

12 May 2020

2561-2570

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6762523&resulttype=core&format=json

12 May 2020

The insulin receptor tyrosine kinase substrate p58/53 and the insulin receptor are components of CNS synapses

1 reference

https://pubmed.ncbi.nlm.nih.gov/11306609

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Diabetes and dementia: is the brain another site of end-organ damage?

1 reference

https://pubmed.ncbi.nlm.nih.gov/11306609

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Association of diabetes mellitus and dementia: the Rotterdam Study.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11306609

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Generation of Alzheimer beta-amyloid protein in the trans-Golgi network in the apparent absence of vesicle formation

1 reference

https://pubmed.ncbi.nlm.nih.gov/11306609

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Detection of a novel intraneuronal pool of insoluble amyloid beta protein that accumulates with time in culture

1 reference

https://pubmed.ncbi.nlm.nih.gov/11306609

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Apolipoprotein-E genotyping of diabetic dementia patients: is diabetes rare in Alzheimer's disease?

1 reference

https://pubmed.ncbi.nlm.nih.gov/11306609

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Recruitment of functional GABA(A) receptors to postsynaptic domains by insulin

1 reference

https://pubmed.ncbi.nlm.nih.gov/11306609

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A synthetic inhibitor of the mitogen-activated protein kinase cascade

1 reference

https://pubmed.ncbi.nlm.nih.gov/11306609

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Localization and characterization of insulin receptors in rat brain and pituitary gland using in vitro autoradiography and computerized densitometry

1 reference

https://pubmed.ncbi.nlm.nih.gov/11306609

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Incidence and risk factors of vascular dementia and Alzheimer's disease in a defined elderly Japanese population: the Hisayama Study

1 reference

https://pubmed.ncbi.nlm.nih.gov/11306609

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Endoplasmic reticulum and trans-Golgi network generate distinct populations of Alzheimer beta-amyloid peptides

1 reference

https://pubmed.ncbi.nlm.nih.gov/11306609

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Intracellular generation and accumulation of amyloid beta-peptide terminating at amino acid 42.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11306609

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular basis of insulin-stimulated GLUT4 vesicle trafficking. Location! Location! Location!

1 reference

https://pubmed.ncbi.nlm.nih.gov/11306609

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

PD 098059 is a specific inhibitor of the activation of mitogen-activated protein kinase kinase in vitro and in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/11306609

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Estrogen reduces neuronal generation of Alzheimer beta-amyloid peptides

1 reference

https://pubmed.ncbi.nlm.nih.gov/11306609

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Insulin-like growth factor-1 and insulin mediate transient site-selective increases in tau phosphorylation in primary cortical neurons

1 reference

https://pubmed.ncbi.nlm.nih.gov/11306609

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Insulin regulates soluble amyloid precursor protein release via phosphatidyl inositol 3 kinase-dependent pathway

1 reference

https://pubmed.ncbi.nlm.nih.gov/11306609

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The regulation of amyloid beta protein precursor secretion and its modulatory role in cell adhesion

1 reference

https://pubmed.ncbi.nlm.nih.gov/11306609

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Diabetics do not have increased Alzheimer-type pathology compared with age-matched control subjects. A retrospective postmortem immunocytochemical and histofluorescent study.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11306609

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Brain insulin and insulin receptors in aging and sporadic Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/11306609

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differential regulation of signaling pathways for insulin and insulin-like growth factor I

1 reference

https://pubmed.ncbi.nlm.nih.gov/11306609

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of insulin degradation by hepatoma cells after microinjection of monoclonal antibodies to a specific cytosolic protease

1 reference

https://pubmed.ncbi.nlm.nih.gov/11306609

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Distinct sites of intracellular production for Alzheimer's disease A beta40/42 amyloid peptides.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11306609

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cerebrospinal fluid and plasma insulin levels in Alzheimer's disease: relationship to severity of dementia and apolipoprotein E genotype

1 reference

https://pubmed.ncbi.nlm.nih.gov/11306609

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The endocrinology of aging.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11306609

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Processing of Alzheimer beta/A4 amyloid precursor protein: modulation by agents that regulate protein phosphorylation

1 reference

https://pubmed.ncbi.nlm.nih.gov/11306609

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A detergent-insoluble membrane compartment contains A beta in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/11306609

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Insulin-degrading enzyme regulates extracellular levels of amyloid beta-protein by degradation

1 reference

https://pubmed.ncbi.nlm.nih.gov/11306609

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neurons regulate extracellular levels of amyloid beta-protein via proteolysis by insulin-degrading enzyme

1 reference

https://pubmed.ncbi.nlm.nih.gov/11306609

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evidence for phosphorylation and oligomeric assembly of presenilin 1.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11306609

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Insulin stimulates both leptin secretion and production by rat white adipose tissue

1 reference

https://pubmed.ncbi.nlm.nih.gov/11306609

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Two compartments for insulin-stimulated exocytosis in 3T3-L1 adipocytes defined by endogenous ACRP30 and GLUT4

1 reference

https://pubmed.ncbi.nlm.nih.gov/11306609

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Analysis of familial and individual risk factors among patients with ischemic vascular dementia and Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/11306609

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Diabetes mellitus and the risk of dementia: The Rotterdam Study.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11306609

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Intracellular APP processing and A beta production in Alzheimer disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/11306609

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Insulin and insulin-like growth factor-1 regulate tau phosphorylation in cultured human neurons.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11306609

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The endocrinology of aging

1 reference

https://pubmed.ncbi.nlm.nih.gov/11306609

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Intraneuronal Abeta42 accumulation in human brain.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11306609

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Abeta42-positive non-pyramidal neurons around amyloid plaques in Alzheimer's disease.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11306609

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Brain insulin receptors and spatial memory. Correlated changes in gene expression, tyrosine phosphorylation, and signaling molecules in the hippocampus of water maze trained rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/11306609

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Low blood pressure and blood glucose levels in Alzheimer's disease. Evidence for a hypometabolic disorder?

1 reference

https://pubmed.ncbi.nlm.nih.gov/11306609

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Insulin metabolism in Alzheimer's disease differs according to apolipoprotein E genotype and gender.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11306609

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tracking insulin to the mind

1 reference

https://pubmed.ncbi.nlm.nih.gov/11306609

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Alzheimer's A beta(1-42) is generated in the endoplasmic reticulum/intermediate compartment of NT2N cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/11306609

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The cell biology of beta-amyloid precursor protein and presenilin in Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/11306609

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Risk of dementia among persons with diabetes mellitus: a population-based cohort study

1 reference

https://pubmed.ncbi.nlm.nih.gov/11306609

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Insulin transiently increases tau phosphorylation: involvement of glycogen synthase kinase-3beta and Fyn tyrosine kinase

1 reference

https://pubmed.ncbi.nlm.nih.gov/11306609

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of amyloid precursor protein cleavage

1 reference

https://pubmed.ncbi.nlm.nih.gov/11306609

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A disturbance in the neuronal insulin receptor signal transduction in sporadic Alzheimer's disease.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11306609

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Generation and regulation of beta-amyloid peptide variants by neurons.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11306609

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Transgenic mice with Alzheimer presenilin 1 mutations show accelerated neurodegeneration without amyloid plaque formation.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11306609

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nerve and epidermal growth factors induce the release of the Alzheimer amyloid precursor from PC 12 cell cultures.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11306609

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of the major Abeta1-42-degrading catabolic pathway in brain parenchyma: suppression leads to biochemical and pathological deposition

1 reference

https://pubmed.ncbi.nlm.nih.gov/11306609

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1523/JNEUROSCI.21-08-02561.2001

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6762523&resulttype=core&format=json

12 May 2020

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6762523&resulttype=core&format=json

12 May 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6762523&resulttype=core&format=json

12 May 2020

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