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Cell-cycle inhibitors: three families united by a common cause

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Europe PubMed Central

PubMed publication ID

29 July 2017

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Europe PubMed Central

Cell-cycle inhibitors: three families united by a common cause (English)

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

1 reference

ORCID Public Data File 2021

author name string

Vidal A

1

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

Koff A

2

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

language of work or name

0 references

publication date

1 April 2000

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

247

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

1-2

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

1-15

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

Cyclin E and c-Myc promote cell proliferation in the presence of p16INK4a and of hypophosphorylated retinoblastoma family proteins.

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2800%2900092-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Differential interaction of the cyclin-dependent kinase (Cdk) inhibitor p27Kip1 with cyclin A-Cdk2 and cyclin D2-Cdk4.

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2800%2900092-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Cell cycle regulation of the murine cyclin E gene depends on an E2F binding site in the promoter.

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2800%2900092-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Retinoblastoma protein recruits histone deacetylase to repress transcription

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2800%2900092-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Radiation-induced cell cycle arrest compromised by p21 deficiency

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2800%2900092-5

7 January 2021

based on heuristic

inferred from DOI database lookup

p21 is a critical CDK2 regulator essential for proliferation control in Rb-deficient cells

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2800%2900092-5

7 January 2021

based on heuristic

inferred from DOI database lookup

TGF-beta1 actions on FRTL-5 cells provide a model for the physiological regulation of thyroid growth.

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2800%2900092-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Oligodendrocyte precursor differentiation is perturbed in the absence of the cyclin-dependent kinase inhibitor p27Kip1.

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2800%2900092-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Dual cyclin-binding domains are required for p107 to function as a kinase inhibitor

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2800%2900092-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Decreased levels of the cell-cycle inhibitor p27Kip1 protein: prognostic implications in primary breast cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2800%2900092-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Identification of human and mouse p19, a novel CDK4 and CDK6 inhibitor with homology to p16ink4

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2800%2900092-5

7 January 2021

based on heuristic

inferred from DOI database lookup

The p21(Cip1) and p27(Kip1) CDK 'inhibitors' are essential activators of cyclin D-dependent kinases in murine fibroblasts

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2800%2900092-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Requirement for a functional Rb-1 gene in murine development

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2800%2900092-5

7 January 2021

based on heuristic

inferred from DOI database lookup

New insights into the tumor suppression function of P27(kip1)

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2800%2900092-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Requirement of p27Kip1 for restriction point control of the fibroblast cell cycle

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2800%2900092-5

7 January 2021

based on heuristic

inferred from DOI database lookup

A new pathway for mitogen-dependent cdk2 regulation uncovered in p27(Kip1)-deficient cells

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2800%2900092-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Shared role of the pRB-related p130 and p107 proteins in limb development

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2800%2900092-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Distinct altered patterns of p27KIP1 gene expression in benign prostatic hyperplasia and prostatic carcinoma

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2800%2900092-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Mice Lacking p21CIP1/WAF1 undergo normal development, but are defective in G1 checkpoint control

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2800%2900092-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Association of human cyclin E with a periodic G1-S phase protein kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2800%2900092-5

7 January 2021

based on heuristic

inferred from DOI database lookup

p53-dependent inhibition of cyclin-dependent kinase activities in human fibroblasts during radiation-induced G1 arrest.

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2800%2900092-5

7 January 2021

based on heuristic

inferred from DOI database lookup

p27Kip1 alters the response of cells to mitogen and is part of a cell-intrinsic timer that arrests the cell cycle and initiates differentiation.

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2800%2900092-5

7 January 2021

based on heuristic

inferred from DOI database lookup

The retinoblastoma protein associates with the protein phosphatase type 1 catalytic subunit

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2800%2900092-5

7 January 2021

based on heuristic

inferred from DOI database lookup

The regulation of E2F by pRB-family proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2800%2900092-5

7 January 2021

based on heuristic

inferred from DOI database lookup

WAF1, a potential mediator of p53 tumor suppression

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2800%2900092-5

7 January 2021

based on heuristic

inferred from DOI database lookup

TGF beta inhibition of Cdk4 synthesis is linked to cell cycle arrest

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2800%2900092-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Regulation of the cell cycle by the Rb tumor suppressor family

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2800%2900092-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Mice lacking cyclin D1 are small and show defects in eye and mammary gland development.

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2800%2900092-5

7 January 2021

based on heuristic

inferred from DOI database lookup

A syndrome of multiorgan hyperplasia with features of gigantism, tumorigenesis, and female sterility in p27(Kip1)-deficient mice

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2800%2900092-5

7 January 2021

based on heuristic

inferred from DOI database lookup

The murine gene p27Kip1 is haplo-insufficient for tumour suppression

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2800%2900092-5

7 January 2021

based on heuristic

inferred from DOI database lookup

The three members of the pocket proteins family share the ability to repress E2F activity through recruitment of a histone deacetylase

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2800%2900092-5

7 January 2021

based on heuristic

inferred from DOI database lookup

CDK inhibitors p18(INK4c) and p27(Kip1) mediate two separate pathways to collaboratively suppress pituitary tumorigenesis

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2800%2900092-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Transcriptional Regulation of the p21(WAF1/CIP1)Gene

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2800%2900092-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Rescue of Cyclin D1 Deficiency by Knockin Cyclin E

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2800%2900092-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Role of the retinoblastoma protein family, pRB, p107 and p130 in the negative control of cell growth

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2800%2900092-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Inhibition of CDK2 activity in vivo by an associated 20K regulatory subunit.

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2800%2900092-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Growth suppression by p18, a p16INK4/MTS1- and p14INK4B/MTS2-related CDK6 inhibitor, correlates with wild-type pRb function

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2800%2900092-5

7 January 2021

based on heuristic

inferred from DOI database lookup

p15INK4B is a potential effector of TGF-beta-induced cell cycle arrest

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2800%2900092-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Cdk phosphorylation triggers sequential intramolecular interactions that progressively block Rb functions as cells move through G1

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2800%2900092-5

7 January 2021

based on heuristic

inferred from DOI database lookup

The p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2800%2900092-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Genomic imprinting of p57KIP2, a cyclin-dependent kinase inhibitor, in mouse

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2800%2900092-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Genomic imprinting of human p57KIP2 and its reduced expression in Wilms' tumors

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2800%2900092-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Translational control of p27Kip1 accumulation during the cell cycle

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2800%2900092-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Novel INK4 proteins, p19 and p18, are specific inhibitors of the cyclin D-dependent kinases CDK4 and CDK6

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2800%2900092-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Differential effects of cdk2 and cdk3 on the control of pRb and E2F function during G1 exit

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2800%2900092-5

7 January 2021

based on heuristic

inferred from DOI database lookup

pRB and p107/p130 are required for the regulated expression of different sets of E2F responsive genes.

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2800%2900092-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Repression of the CDK activator Cdc25A and cell-cycle arrest by cytokine TGF-beta in cells lacking the CDK inhibitor p15

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2800%2900092-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Effects of an Rb mutation in the mouse

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2800%2900092-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Multistep regulation of DNA replication by Cdk phosphorylation of HsCdc6

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2800%2900092-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Analysis of the p16 gene (CDKN2) as a candidate for the chromosome 9p melanoma susceptibility locus

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2800%2900092-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Tumor suppression at the mouse INK4a locus mediated by the alternative reading frame product p19ARF

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2800%2900092-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Cyclic AMP-induced G1 phase arrest mediated by an inhibitor (p27Kip1) of cyclin-dependent kinase 4 activation.

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2800%2900092-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Enhanced growth of mice lacking the cyclin-dependent kinase inhibitor function of p27(Kip1).

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2800%2900092-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Formation and activation of a cyclin E-cdk2 complex during the G1 phase of the human cell cycle

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2800%2900092-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Negative regulation of G1 in mammalian cells: inhibition of cyclin E-dependent kinase by TGF-beta.

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2800%2900092-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Tumour-derived p16 alleles encoding proteins defective in cell-cycle inhibition

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2800%2900092-5

7 January 2021

based on heuristic

inferred from DOI database lookup

p27(Kip1) induction and inhibition of proliferation by the intracellular Ah receptor in developing thymus and hepatoma cells

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2800%2900092-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Strain-dependent myeloid hyperplasia, growth deficiency, and accelerated cell cycle in mice lacking the Rb-related p107 gene.

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2800%2900092-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Mice deficient for Rb are nonviable and show defects in neurogenesis and haematopoiesis

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2800%2900092-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Cloning of p57KIP2, a cyclin-dependent kinase inhibitor with unique domain structure and tissue distribution

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2800%2900092-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Targeted disruption of p107: functional overlap between p107 and Rb

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2800%2900092-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Genes in the RB pathway and their knockout in mice

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2800%2900092-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Increased proteasome-dependent degradation of the cyclin-dependent kinase inhibitor p27 in aggressive colorectal carcinomas.

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2800%2900092-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Gene disruption of p27(Kip1) allows cell proliferation in the postnatal and adult organ of corti

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2800%2900092-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Specific enzymatic dephosphorylation of the retinoblastoma protein

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2800%2900092-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Cyclin E-induced S phase without activation of the pRb/E2F pathway.

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2800%2900092-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Retinoblastoma-protein-dependent cell-cycle inhibition by the tumour suppressor p16

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2800%2900092-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Functional inactivation of the retinoblastoma protein requires sequential modification by at least two distinct cyclin-cdk complexes

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2800%2900092-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Cell-cycle inhibition by independent CDK and PCNA binding domains in p21Cip1

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2800%2900092-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Rb interacts with histone deacetylase to repress transcription

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2800%2900092-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Rapamycin resistance tied to defective regulation of p27Kip1.

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2800%2900092-5

7 January 2021

based on heuristic

inferred from DOI database lookup

p53-dependent and independent expression of p21 during cell growth, differentiation, and DNA damage

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2800%2900092-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Retinoblastoma protein represses transcription by recruiting a histone deacetylase

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2800%2900092-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Induced expression of p16(INK4a) inhibits both CDK4- and CDK2-associated kinase activity by reassortment of cyclin-CDK-inhibitor complexes

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2800%2900092-5

7 January 2021

based on heuristic

inferred from DOI database lookup

p57KIP2, a structurally distinct member of the p21CIP1 Cdk inhibitor family, is a candidate tumor suppressor gene

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2800%2900092-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Imprinting of the gene encoding a human cyclin-dependent kinase inhibitor, p57KIP2, on chromosome 11p15

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2800%2900092-5

7 January 2021

based on heuristic

inferred from DOI database lookup

D-type cyclin-dependent kinase activity in mammalian cells

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2800%2900092-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Growth suppression by p16ink4 requires functional retinoblastoma protein

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2800%2900092-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Enhanced ribosomal association of p27(Kip1) mRNA is a mechanism contributing to accumulation during growth arrest.

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2800%2900092-5

7 January 2021

based on heuristic

inferred from DOI database lookup

E2F-4 switches from p130 to p107 and pRB in response to cell cycle reentry

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2800%2900092-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Cyclin-dependent kinases: engines, clocks, and microprocessors

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2800%2900092-5

7 January 2021

based on heuristic

inferred from DOI database lookup

The retinoblastoma gene family: cousins with overlapping interests

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2800%2900092-5

7 January 2021

based on heuristic

inferred from DOI database lookup

p130 is dispensable in peripheral T lymphocytes: evidence for functional compensation by p107 and pRB.

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2800%2900092-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Mice lacking p27(Kip1) display increased body size, multiple organ hyperplasia, retinal dysplasia, and pituitary tumors

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2800%2900092-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Cell-free degradation of p27(kip1), a G1 cyclin-dependent kinase inhibitor, is dependent on CDK2 activity and the proteasome

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2800%2900092-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Early loss of the retinoblastoma gene is associated with impaired growth inhibitory innervation during melanotroph carcinogenesis in Rb+/- mice

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2800%2900092-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Cloning of senescent cell-derived inhibitors of DNA synthesis using an expression screen

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2800%2900092-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Regulation of the cyclin E gene by transcription factor E2F1

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2800%2900092-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Cyclin-dependent regulation of G1 in mammalian fibroblasts.

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2800%2900092-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Human cyclin E, a nuclear protein essential for the G1-to-S phase transition

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2800%2900092-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Role of the ubiquitin-proteasome pathway in regulating abundance of the cyclin-dependent kinase inhibitor p27

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2800%2900092-5

7 January 2021

based on heuristic

inferred from DOI database lookup

G1 events and regulation of cell proliferation

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2800%2900092-5

7 January 2021

based on heuristic

inferred from DOI database lookup

p27 and Rb are on overlapping pathways suppressing tumorigenesis in mice.

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2800%2900092-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Cyclin D-CDK subunit arrangement is dependent on the availability of competing INK4 and p21 class inhibitors

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2800%2900092-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Mechanisms of cyclin-dependent kinase regulation: structures of Cdks, their cyclin activators, and Cip and INK4 inhibitors

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2800%2900092-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Ras signalling linked to the cell-cycle machinery by the retinoblastoma protein

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2800%2900092-5

7 January 2021

based on heuristic

inferred from DOI database lookup

p27Kip1, a cyclin-Cdk inhibitor, links transforming growth factor-beta and contact inhibition to cell cycle arrest

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2800%2900092-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Cloning of p27Kip1, a cyclin-dependent kinase inhibitor and a potential mediator of extracellular antimitogenic signals

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2800%2900092-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Expression of cell-cycle regulators p27Kip1 and cyclin E, alone and in combination, correlate with survival in young breast cancer patients

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2800%2900092-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Overexpression of mouse D-type cyclins accelerates G1 phase in rodent fibroblasts

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2800%2900092-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Loss of Cdk4 expression causes insulin-deficient diabetes and Cdk4 activation results in beta-islet cell hyperplasia

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2800%2900092-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Acceleration of the G1/S phase transition by expression of cyclins D1 and E with an inducible system

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2800%2900092-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Kip/Cip and Ink4 Cdk inhibitors cooperate to induce cell cycle arrest in response to TGF-beta

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2800%2900092-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Abrogation of p27Kip1 by cDNA antisense suppresses quiescence (G0 state) in fibroblasts

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2800%2900092-5

7 January 2021

based on heuristic

inferred from DOI database lookup

p107 is a suppressor of retinoblastoma development in pRb-deficient mice

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2800%2900092-5

7 January 2021

based on heuristic

inferred from DOI database lookup

The INK4 family of cell cycle inhibitors in cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2800%2900092-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Stable binding to E2F is not required for the retinoblastoma protein to activate transcription, promote differentiation, and suppress tumor cell growth

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2800%2900092-5

7 January 2021

based on heuristic

inferred from DOI database lookup

A new regulatory motif in cell-cycle control causing specific inhibition of cyclin D/CDK4

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2800%2900092-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Role of the INK4a locus in tumor suppression and cell mortality.

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2800%2900092-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Cyclin E-CDK2 is a regulator of p27Kip1.

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2800%2900092-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Mammalian G1 cyclins

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2800%2900092-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Cancer cell cycles

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2800%2900092-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Tumor surveillance via the ARF-p53 pathway.

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2800%2900092-5

7 January 2021

based on heuristic

inferred from DOI database lookup

CDK inhibitors: positive and negative regulators of G1-phase progression

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2800%2900092-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Cyclin D1 provides a link between development and oncogenesis in the retina and breast

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2800%2900092-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Cyclin D2 is an FSH-responsive gene involved in gonadal cell proliferation and oncogenesis

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2800%2900092-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Inactivation of the cyclin-dependent kinase inhibitor p27 upon loss of the tuberous sclerosis complex gene-2

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2800%2900092-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Cell cycle control of DNA replication.

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2800%2900092-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Inactivation of pRB-related proteins p130 and p107 mediated by the J domain of simian virus 40 large T antigen.

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2800%2900092-5

7 January 2021

based on heuristic

inferred from DOI database lookup

p27, a novel inhibitor of G1 cyclin-Cdk protein kinase activity, is related to p21

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2800%2900092-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Mutation of E2f-1 suppresses apoptosis and inappropriate S phase entry and extends survival of Rb-deficient mouse embryos

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2800%2900092-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Targeted disruption of CDK4 delays cell cycle entry with enhanced p27(Kip1) activity

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2800%2900092-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Phosphorylation-dependent degradation of the cyclin-dependent kinase inhibitor p27

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2800%2900092-5

7 January 2021

based on heuristic

inferred from DOI database lookup

HuR regulates p21 mRNA stabilization by UV light

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2800%2900092-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Mechanism of active transcriptional repression by the retinoblastoma protein

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2800%2900092-5

7 January 2021

based on heuristic

inferred from DOI database lookup

p130 and p107 use a conserved domain to inhibit cellular cyclin-dependent kinase activity

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2800%2900092-5

7 January 2021

based on heuristic

inferred from DOI database lookup

p21 is a universal inhibitor of cyclin kinases

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2800%2900092-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Ablation of the CDK inhibitor p57Kip2 results in increased apoptosis and delayed differentiation during mouse development.

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2800%2900092-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Role of pRb-related proteins in simian virus 40 large-T-antigen-mediated transformation

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2800%2900092-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Proliferating cell nuclear antigen and p21 are components of multiple cell cycle kinase complexes

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2800%2900092-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Altered cell differentiation and proliferation in mice lacking p57KIP2 indicates a role in Beckwith–Wiedemann syndrome

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2800%2900092-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Cooperation between the Cdk inhibitors p27(KIP1) and p57(KIP2) in the control of tissue growth and development

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2800%2900092-5

7 January 2021

based on heuristic

inferred from DOI database lookup

p21(CIP1) and p57(KIP2) control muscle differentiation at the myogenin step

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2800%2900092-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Expression of NPAT, a novel substrate of cyclin E-CDK2, promotes S-phase entry

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2800%2900092-5

7 January 2021

based on heuristic

inferred from DOI database lookup

p107 uses a p21CIP1-related domain to bind cyclin/cdk2 and regulate interactions with E2F.

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2800%2900092-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Postnatal neuronal proliferation in mice lacking Ink4d and Kip1 inhibitors of cyclin-dependent kinases

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2800%2900092-5

7 January 2021

based on heuristic

inferred from DOI database lookup

INK4d-deficient mice are fertile despite testicular atrophy

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2800%2900092-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Identifiers

10.1016/S0378-1119(00)00092-5

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

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