(Q33889312)

29 July 2017

title

BMP-4 is proteolytically activated by furin and/or PC6 during vertebrate embryonic development (English)

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29 July 2017

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Y Cui

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29 July 2017

F Jean

series ordinal

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29 July 2017

G Thomas

series ordinal

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29 July 2017

J L Christian

series ordinal

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29 July 2017

language of work or name

English

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publication date

1 August 1998

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29 July 2017

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29 July 2017

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29 July 2017

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29 July 2017

page(s)

4735-4743

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TGF-beta signalling through the Smad pathway

29 July 2017

cites work

1 reference

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5 July 2018

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Furin: a mammalian subtilisin/Kex2p-like endoprotease involved in processing of a wide variety of precursor proteins

5 July 2018

1 reference

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Cellular interpretation of multiple TGF-beta signals: intracellular antagonism between activin/BVg1 and BMP-2/4 signaling mediated by Smads

5 July 2018

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TGF-beta signalling from cell membrane to nucleus through SMAD proteins

5 July 2018

1 reference

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Eukaryotic protein processing: endoproteolysis of precursor proteins

5 July 2018

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Impaired fertility in mice deficient for the testicular germ-cell protease PC4

5 July 2018

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Vertebrate neural induction: inducers, inhibitors, and a new synthesis

5 July 2018

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Xnr4: a Xenopus nodal-related gene expressed in the Spemann organizer

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170802

Activation of the furin endoprotease is a multiple-step process: requirements for acidification and internal propeptide cleavage

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170802

Embryonic patterning: to BMP or not to BMP, that is the question

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170802

The developmental expression in the rat CNS and peripheral tissues of proteases PC5 and PACE4 mRNAs: comparison with other proprotein processing enzymes.

5 July 2018

1 reference

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Synergistic effects of Vg1 and Wnt signals in the specification of dorsal mesoderm and endoderm

5 July 2018

1 reference

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Signalling by TGF-beta family members: short-range effects of Xnr-2 and BMP-4 contrast with the long-range effects of activin.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170802

SPC4, SPC6, and the novel protease SPC7 are coexpressed with bone morphogenetic proteins at distinct sites during embryogenesis.

5 July 2018

1 reference

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Bone morphogenetic proteins: multifunctional regulators of vertebrate development

5 July 2018

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The secreted product of Xenopus gene lunatic Fringe, a vertebrate signaling molecule

5 July 2018

1 reference

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Modulation of furin-mediated proprotein processing activity by site-directed mutagenesis.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170802

Differential processing of proenkephalin by prohormone convertases 1(3) and 2 and furin

5 July 2018

1 reference

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Vg1 and regional specification in vertebrates: a new role for an old molecule

5 July 2018

1 reference

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On the function of BMP-4 in patterning the marginal zone of the Xenopus embryo.

5 July 2018

1 reference

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Expression of achaete-scute homolog 3 in Xenopus embryos converts ectodermal cells to a neural fate

5 July 2018

1 reference

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Potent ectopic bone-inducing activity of bone morphogenetic protein-4/7 heterodimer

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170802

Processing of transforming growth factor beta 1 precursor by human furin convertase

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170802

Studies with a Xenopus BMP receptor suggest that ventral mesoderm-inducing signals override dorsal signals in vivo

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170802

Intracellular trafficking and activation of the furin proprotein convertase: localization to the TGN and recycling from the cell surface

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170802

Monoclonal antibodies identify blastemal cells derived from dedifferentiating muscle in newt limb regeneration

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170802

Functional messenger RNAs are produced by SP6in vitrotranscription of cloned cDNAs

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170802

The Xenopus XIHbox 6 homeo protein, a marker of posterior neural induction, is expressed in proliferating neurons

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170802

Xwnt-8, a Xenopus Wnt-1/int-1-related gene responsive to mesoderm-inducing growth factors, may play a role in ventral mesodermal patterning during embryogenesis.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170802

Prohormone processing in Xenopus oocytes: characterization of cleavage signals and cleavage enzymes

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170802

Molecular nature of Spemann's organizer: the role of the Xenopus homeobox gene goosecoid

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170802

Human furin is a calcium-dependent serine endoprotease that recognizes the sequence Arg-X-X-Arg and efficiently cleaves anthrax toxin protective antigen

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170802

The new enzymology of precursor processing endoproteases

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170802

Ventral ectoderm of Xenopus forms neural tissue, including hindbrain, in response to activin

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170802

Identification of the fourth member of the mammalian endoprotease family homologous to the yeast Kex2 protease. Its testis-specific expression

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170802

Xenopus Smad8 acts downstream of BMP-4 to modulate its activity during vertebrate embryonic patterning

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170802

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170802

The developmental expression in rat of proteases furin, PC1, PC2, and carboxypeptidase E: implications for early maturation of proteolytic processing capacity.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170802

The bli-4 locus of Caenorhabditis elegans encodes structurally distinct kex2/subtilisin-like endoproteases essential for early development and adult morphology

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170802

Induction of dorsal mesoderm by soluble, mature Vg1 protein

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170802

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170802

bFGF as a possible morphogen for the anteroposterior axis of the central nervous system in Xenopus.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170802

A truncated activin receptor inhibits mesoderm induction and formation of axial structures in Xenopus embryos

29 October 2018

1 reference

12 December 2020

6 Active-site titration of peptidases

1 reference

12 December 2020

Fluorescent Peptidyl Substrates as an Aid in Studying the Substrate Specificity of Human Prohormone Convertase PC1 and Human Furin and Designing a Potent Irreversible Inhibitor

1 reference

12 December 2020

Growth factors in development: the role of TGF-beta related polypeptide signalling molecules in embryogenesis

1 reference

12 December 2020

Identifiers

DOI

10.1093/EMBOJ/17.16.4735

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29 July 2017

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29 July 2017

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