(Q33877218)

29 July 2017

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title

Understanding Ras: 'it ain't over 'til it's over'. (English)

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29 July 2017

Shields JM

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29 July 2017

Pruitt K

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29 July 2017

McFall A

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29 July 2017

Shaub A

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29 July 2017

Der CJ

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29 July 2017

publication date

1 April 2000

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29 July 2017

published in

Trends in Cell Biology

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29 July 2017

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29 July 2017

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29 July 2017

page(s)

147-154

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Evidence for a Ras/Ral signaling cascade

29 July 2017

cites work

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Mechanisms and consequences of activation of protein kinase B/Akt

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Increasing complexity of Ras signaling.

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Rho family proteins and Ras transformation: the RHOad less traveled gets congested.

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7 January 2021

Ras caught in another affair: the exchange factors for Ral.

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7 January 2021

New insights into the interaction of Ras with the plasma membrane

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7 January 2021

How do small GTPase signal transduction pathways regulate cell cycle entry?

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7 January 2021

Akt is more than just a Bad kinase

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7 January 2021

Mitogenic signaling mediated by oxidants in Ras-transformed fibroblasts

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7 January 2021

NF-kappaB is a target of AKT in anti-apoptotic PDGF signalling

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NF-kappaB activation by tumour necrosis factor requires the Akt serine-threonine kinase

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7 January 2021

Requirement of NF-kappaB activation to suppress p53-independent apoptosis induced by oncogenic Ras.

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7 January 2021

Control of adhesion-dependent cell survival by focal adhesion kinase

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7 January 2021

Matrix adhesion and Ras transformation both activate a phosphoinositide 3-OH kinase and protein kinase B/Akt cellular survival pathway

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7 January 2021

Senescence of human fibroblasts induced by oncogenic Raf.

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7 January 2021

Premature senescence involving p53 and p16 is activated in response to constitutive MEK/MAPK mitogenic signaling

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7 January 2021

Signaling through mitogen-activated protein kinase and Rac/Rho does not duplicate the effects of activated Ras on skeletal myogenesis

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7 January 2021

Multiple ras effector pathways contribute to G(1) cell cycle progression

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7 January 2021

Rho GTPases and signaling networks

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7 January 2021

Coupling of Ras and Rac guanosine triphosphatases through the Ras exchanger Sos.

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7 January 2021

The exchange factor Ras-GRF2 activates Ras-dependent and Rac-dependent mitogen-activated protein kinase pathways

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7 January 2021

EPS8 and E3B1 transduce signals from Ras to Rac

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7 January 2021

Signals from Ras and Rho GTPases interact to regulate expression of p21Waf1/Cip1.

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7 January 2021

Possible involvement of the inactivation of the Rho-Rho-kinase pathway in oncogenic Ras-induced transformation.

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7 January 2021

Transformation mediated by RhoA requires activity of ROCK kinases

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7 January 2021

A new member of the Rho family, Rnd1, promotes disassembly of actin filament structures and loss of cell adhesion

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7 January 2021

RhoE regulates actin cytoskeleton organization and cell migration.

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7 January 2021

Tyrosine phosphorylation regulates the adhesions of ras-transformed breast epithelia

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7 January 2021

Oncogenic Ras activation of Raf/mitogen-activated protein kinase-independent pathways is sufficient to cause tumorigenic transformation

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7 January 2021

Activation of the Raf-1/MAP kinase cascade is not sufficient for Ras transformation of RIE-1 epithelial cells

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7 January 2021

Ras, but not Src, transformation of RIE-1 epithelial cells is dependent on activation of the mitogen-activated protein kinase cascade

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7 January 2021

Activation of mitogen-activated protein kinase is necessary but not sufficient for proliferation of human thyroid epithelial cells induced by mutant Ras.

1 reference

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7 January 2021

Ral-specific guanine nucleotide exchange factor activity opposes other Ras effectors in PC12 cells by inhibiting neurite outgrowth

1 reference

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7 January 2021

Suppression of c-Myc-induced apoptosis by Ras signalling through PI(3)K and PKB.

1 reference

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7 January 2021

Differential contribution of the ERK and JNK mitogen-activated protein kinase cascades to Ras transformation of HT1080 fibrosarcoma and DLD-1 colon carcinoma cells

1 reference

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7 January 2021

Blockade of the MAP kinase pathway suppresses growth of colon tumors in vivo

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7 January 2021

p21ras initiates Rac-1 but not phosphatidyl inositol 3 kinase/PKB, mediated signaling pathways in T lymphocytes

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7 January 2021

Studying cancer in the mouse

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7 January 2021

Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a

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7 January 2021

Stepwise transformation of primary thyroid epithelial cells by a mutant Ha-ras oncogene: an in vitro model of tumor progression

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7 January 2021

Creation of human tumour cells with defined genetic elements

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7 January 2021

Absence of cancer-associated changes in human fibroblasts immortalized with telomerase

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7 January 2021

K-ras is an essential gene in the mouse with partial functional overlap with N-ras

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7 January 2021

Endomembrane trafficking of ras: the CAAX motif targets proteins to the ER and Golgi

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7 January 2021

Modulation of phagosome biogenesis by Legionella pneumophila creates an organelle permissive for intracellular growth

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7 January 2021

Tools of the trade: use of dominant-inhibitory mutants of Ras-family GTPases

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2800%2901740-2

7 January 2021

Suppression of Ras-induced apoptosis by the Rac GTPase

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2800%2901740-2

7 January 2021

Cell cycle-dependent activation of Ras.

1 reference

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7 January 2021

10.1016/S0962-8924(00)01740-2

Identifiers

DOI

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29 July 2017

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