(Q33859512)

29 July 2017

title

Ultra-deep sequencing of mouse mitochondrial DNA: mutational patterns and their origins (English)

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29 July 2017

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Christoph Freyer

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James B Stewart

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Adam Ameur

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Nils-Göran Larsson

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29 July 2017

Ulf Gyllensten

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29 July 2017

Erik Hagström

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29 July 2017

Max Ingman

series ordinal

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29 July 2017

publication date

24 March 2011

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29 July 2017

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29 July 2017

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29 July 2017

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29 July 2017

page(s)

e1002028

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Creative Commons Attribution 4.0 International

29 July 2017

start time

24 March 2011

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April 2022 Public Data File from Crossref

copyrighted

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cites work

The mtDNA mutation spectrum of the progeroid Polg mutator mouse includes abundant control region multimers

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3063763

Mitochondrial fusion is required for mtDNA stability in skeletal muscle and tolerance of mtDNA mutations

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3063763

Somatic mitochondrial DNA mutations in mammalian aging

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3063763

Global and unbiased detection of splice junctions from RNA-seq data

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3063763

Heteroplasmic mitochondrial DNA mutations in normal and tumour cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3063763

Random point mutations with major effects on protein-coding genes are the driving force behind premature aging in mtDNA mutator mice.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3063763

A comparative approach shows differences in patterns of numt insertion during hominoid evolution

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3063763

Do mtDNA deletions drive premature aging in mtDNA mutator mice?

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3063763

Mice expressing an error-prone DNA polymerase in mitochondria display elevated replication pausing and chromosomal breakage at fragile sites of mitochondrial DNA.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3063763

Pathogenic mitochondrial DNA mutations are common in the general population

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3063763

Somatic mtDNA mutations and aging--facts and fancies

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3063763

Strong purifying selection in transmission of mammalian mitochondrial DNA

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3063763

The ageing mitochondrial genome

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3063763

DNA replication and transcription in mammalian mitochondria

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3063763

Somatic mtDNA mutations cause aging phenotypes without affecting reactive oxygen species production

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3063763

Mutant mitochondrial helicase Twinkle causes multiple mtDNA deletions and a late-onset mitochondrial disease in mice

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3063763

Mitochondrial DNA mutations, oxidative stress, and apoptosis in mammalian aging

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3063763

Premature ageing in mice expressing defective mitochondrial DNA polymerase

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3063763

Revisiting the mouse mitochondrial DNA sequence

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3063763

Mitochondrial mutational spectra in human cells and tissues

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3063763

Mitochondrial role in cell aging

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3063763

The biologic clock: the mitochondria?

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3063763

Increase of deleted mitochondrial DNA in the striatum in Parkinson's disease and senescence

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3063763

Detection of a specific mitochondrial DNA deletion in tissues of older humans

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3063763

Ageing-associated 5 kb deletion in human liver mitochondrial DNA.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3063763

Transcription and translation of deleted mitochondrial genomes in Kearns-Sayre syndrome: implications for pathogenesis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3063763

Accumulation of mtDNA defects and changes in mtDNA content in mouse and rat tissues with aging

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3063763

Detecting heteroplasmy from high-throughput sequencing of complete human mitochondrial DNA genomes

5 July 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1002028

Origins of human mitochondrial point mutations as DNA polymerase gamma-mediated errors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1002028

Mitochondrial point mutations do not limit the natural lifespan of mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1002028

Deletions of muscle mitochondrial DNA in patients with mitochondrial myopathies

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1002028

On mitochondria, mutations, and methodology

21 January 2018

1 reference

12 December 2020

Response: Point Mutations Are Causing Progeroid Phenotypes in the mtDNA Mutator Mouse

1 reference

12 December 2020

High levels of mitochondrial DNA deletions in skeletal muscle of old rhesus monkeys

1 reference

12 December 2020

Generation of mice with mitochondrial dysfunction by introducing mouse mtDNA carrying a deletion into zygotes

1 reference

12 December 2020

Age-dependent increase in deleted mitochondrial DNA in the human heart: possible contributory factor to presbycardia

1 reference

12 December 2020

Deleted mitochondrial DNA in the skeletal muscle of aged individuals

1 reference

12 December 2020

DNA deletions and clonal mutations drive premature aging in mitochondrial mutator mice

1 reference

12 December 2020

10.1371/JOURNAL.PGEN.1002028

Identifiers

DOI

1 reference

29 July 2017

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29 July 2017

1 reference