(Q33846180)

29 July 2017

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title

Significance of multiple mutations in cancer (English)

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29 July 2017

Loeb KR

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29 July 2017

Loeb LA

series ordinal

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29 July 2017

language of work or name

English

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publication date

1 March 2000

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29 July 2017

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29 July 2017

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29 July 2017

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29 July 2017

page(s)

379-385

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The causes and prevention of cancer

29 July 2017

cites work

1 reference

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21 January 2018

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Thymine glycol and thymidine glycol in human and rat urine: a possible assay for oxidative DNA damage

21 January 2018

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Urinary 8-hydroxy-2'-deoxyguanosine as a biological marker of in vivo oxidative DNA damage

21 January 2018

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Mutagenic and genotoxic effects of three vinyl chloride-induced DNA lesions: 1,N6-ethenoadenine, 3,N4-ethenocytosine, and 4-amino-5-(imidazol-2-yl)imidazole.

21 January 2018

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Insertion of specific bases during DNA synthesis past the oxidation-damaged base 8-oxodG

21 January 2018

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Errors in DNA synthesis: a source of spontaneous mutations

21 January 2018

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21 January 2018

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DNA-replication fidelity, mismatch repair and genome instability in cancer cells

21 January 2018

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DNA polymerases alpha, delta, and epsilon: three distinct enzymes from HeLa cells

21 January 2018

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A DNA polymerase alpha pause site is a hot spot for nucleotide misinsertion

21 January 2018

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21 January 2018

DNA mismatch correction

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Specific binding of human MSH2.MSH6 mismatch-repair protein heterodimers to DNA incorporating thymine- or uracil-containing UV light photoproducts opposite mismatched bases.

21 January 2018

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DNA polymerase beta expression differences in selected human tumors and cell lines

21 January 2018

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Dominant negative rat DNA polymerase beta mutants interfere with base excision repair in Saccharomyces cerevisiae

21 January 2018

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Biochemical basis of SOS-induced mutagenesis in Escherichia coli: reconstitution of in vitro lesion bypass dependent on the UmuD'2C mutagenic complex and RecA protein.

21 January 2018

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UmuD'(2)C is an error-prone DNA polymerase, Escherichia coli pol V.

21 January 2018

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Xeroderma pigmentosum variant (XP-V) correcting protein from HeLa cells has a thymine dimer bypass DNA polymerase activity

21 January 2018

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hRAD30 mutations in the variant form of xeroderma pigmentosum

21 January 2018

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Cell cycle control and cancer

21 January 2018

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Transcriptional activation by p53 correlates with suppression of growth but not transformation.

21 January 2018

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The clonal evolution of tumor cell populations

21 January 2018

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Differences in the rates of gene amplification in nontumorigenic and tumorigenic cell lines as measured by Luria-Delbrück fluctuation analysis

21 January 2018

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Isolation and characterization of allelic losses and gains in colorectal tumors by arbitrarily primed polymerase chain reaction

21 January 2018

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Ubiquitous somatic mutations in simple repeated sequences reveal a new mechanism for colonic carcinogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F21.3.379

Somatic frameshift mutations in the BAX gene in colon cancers of the microsatellite mutator phenotype.

21 January 2018

1 reference

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Inactivation of the type II TGF-beta receptor in colon cancer cells with microsatellite instability

21 January 2018

1 reference

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The human mutator gene homolog MSH2 and its association with hereditary nonpolyposis colon cancer

21 January 2018

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Incidence and functional consequences of hMLH1 promoter hypermethylation in colorectal carcinoma

21 January 2018

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Induction of microsatellite instability by oxidative DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F21.3.379

Conditional mutator phenotypes in hMSH2-deficient tumor cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F21.3.379

Detection and mapping of amplified DNA sequences in breast cancer by comparative genomic hybridization

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F21.3.379

Wild-type p53 is a cell cycle checkpoint determinant following irradiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F21.3.379

Genetic instability of cancer cells is proportional to their degree of aneuploidy

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F21.3.379

Chemical induction of mitotic checkpoint override in mammalian cells results in aneuploidy following a transient tetraploid state.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F21.3.379

Genetic instability in colorectal cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F21.3.379

Mutations of mitotic checkpoint genes in human cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F21.3.379

S. cerevisiae genes required for cell cycle arrest in response to loss of microtubule function

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F21.3.379

Expression of Bcl-xL and loss of p53 can cooperate to overcome a cell cycle checkpoint induced by mitotic spindle damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F21.3.379

Characterization of the p53-dependent postmitotic checkpoint following spindle disruption

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F21.3.379

p21(Waf1/Cip1) inhibition of cyclin E/Cdk2 activity prevents endoreduplication after mitotic spindle disruption

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F21.3.379

Mitotic forces control a cell-cycle checkpoint

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F21.3.379

Characterization of MAD2B and other mitotic spindle checkpoint genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F21.3.379

Mutation analysis of hBUB1 in aneuploid HNSCC and lung cancer cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F21.3.379

Mitotic checkpoint inactivation fosters transformation in cells lacking the breast cancer susceptibility gene, Brca2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F21.3.379

Proliferation of mutators in A cell population

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F21.3.379

Role of mutator alleles in adaptive evolution.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F21.3.379

A checkpoint on the road to cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F21.3.379

21 January 2018

Identifiers

DOI

10.1093/CARCIN/21.3.379

1 reference

29 July 2017

1 reference