(Q33734562)

29 July 2017

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title

DNA topoisomerase I in oncology: Dr Jekyll or Mr Hyde? (English)

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29 July 2017

Larsen AK

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29 July 2017

Gobert C

series ordinal

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29 July 2017

publication date

1 January 1999

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Pathology Oncology Research

29 July 2017

published in

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29 July 2017

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29 July 2017

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29 July 2017

page(s)

171-178

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Specific phosphorylation of SR proteins by mammalian DNA topoisomerase I.

29 July 2017

cites work

1 reference

https://api.crossref.org/works/10.1053%2FPAOR.1999.0209

Interaction between DNA and an Escherichia coli protein omega

21 January 2018

1 reference

https://api.crossref.org/works/10.1053%2FPAOR.1999.0209

An activity from mammalian cells that untwists superhelical DNA--a possible swivel for DNA replication (polyoma-ethidium bromide-mouse-embryo cells-dye binding assay).

21 January 2018

1 reference

https://api.crossref.org/works/10.1053%2FPAOR.1999.0209

Drosophihlatopoisomerase I: isolation, purificatioann and characterization

21 January 2018

1 reference

https://api.crossref.org/works/10.1053%2FPAOR.1999.0209

Identification of a vaccinia virus gene encoding a type I DNA topoisomerase

21 January 2018

1 reference

https://api.crossref.org/works/10.1053%2FPAOR.1999.0209

A hyper-recombination mutation in S. cerevisiae identifies a novel eukaryotic topoisomerase

21 January 2018

1 reference

https://api.crossref.org/works/10.1053%2FPAOR.1999.0209

Human TOP3: a single-copy gene encoding DNA topoisomerase III

21 January 2018

1 reference

https://api.crossref.org/works/10.1053%2FPAOR.1999.0209

Biochemical and biophysical analyses of recombinant forms of human topoisomerase I

21 January 2018

1 reference

https://api.crossref.org/works/10.1053%2FPAOR.1999.0209

Crystal structures of human topoisomerase I in covalent and noncovalent complexes with DNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1053%2FPAOR.1999.0209

Interaction between the N-terminal domain of human DNA topoisomerase I and the arginine-serine domain of its substrate determines phosphorylation of SF2/ASF splicing factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1053%2FPAOR.1999.0209

The C-terminal domain but not the tyrosine 723 of human DNA topoisomerase I active site contributes to kinase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1053%2FPAOR.1999.0209

Human DNA topoisomerase I is encoded by a single-copy gene that maps to chromosome region 20q12-13.2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1053%2FPAOR.1999.0209

Structural characterization of the human DNA topoisomerase I gene promoter

21 January 2018

1 reference

https://api.crossref.org/works/10.1053%2FPAOR.1999.0209

The promoter region of the human type-I-DNA-topoisomerase gene. Protein-binding sites and sequences involved in transcriptional regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1053%2FPAOR.1999.0209

Expression of the topoisomerase I gene in serum stimulated human fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1053%2FPAOR.1999.0209

Differential expression of DNA topoisomerases I and II during the eukaryotic cell cycle

21 January 2018

1 reference

https://api.crossref.org/works/10.1053%2FPAOR.1999.0209

Cell cycle analysis of amount and distribution of nuclear DNA topoisomerase I as determined by fluorescence digital imaging microscopy

21 January 2018

1 reference

https://api.crossref.org/works/10.1053%2FPAOR.1999.0209

Essential roles of the RNA polymerase I largest subunit and DNA topoisomerases in the formation of fission yeast nucleolus

21 January 2018

1 reference

https://api.crossref.org/works/10.1053%2FPAOR.1999.0209

Cell cycle-coupled relocation of types I and II topoisomerases and modulation of catalytic enzyme activities

21 January 2018

1 reference

https://api.crossref.org/works/10.1053%2FPAOR.1999.0209

Cloning, characterization, and sequence of the yeast DNA topoisomerase I gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1053%2FPAOR.1999.0209

Function of DNA topoisomerases as replication swivels in Saccharomyces cerevisiae

21 January 2018

1 reference

https://api.crossref.org/works/10.1053%2FPAOR.1999.0209

DNA topoisomerase I is essential in Drosophila melanogaster

21 January 2018

1 reference

https://api.crossref.org/works/10.1053%2FPAOR.1999.0209

Targeted disruption of the mouse topoisomerase I gene by camptothecin selection

21 January 2018

1 reference

https://api.crossref.org/works/10.1053%2FPAOR.1999.0209

Roles of DNA topoisomerases in simian virus 40 DNA replication in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1053%2FPAOR.1999.0209

Topoisomerase I interacts with transcribed regions in Drosophila cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1053%2FPAOR.1999.0209

Role of DNA topoisomerase I in the transcription of supercoiled rRNA gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1053%2FPAOR.1999.0209

DNA topoisomerase I is involved in both repression and activation of transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1053%2FPAOR.1999.0209

Topoisomerase I enhances TFIID-TFIIA complex assembly during activation of transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1053%2FPAOR.1999.0209

Identification of human DNA topoisomerase I as a cofactor for activator-dependent transcription by RNA polymerase II.

21 January 2018

1 reference

https://api.crossref.org/works/10.1053%2FPAOR.1999.0209

Association of crossover points with topoisomerase I cleavage sites: a model for nonhomologous recombination

21 January 2018

1 reference

https://api.crossref.org/works/10.1053%2FPAOR.1999.0209

Conservation of structure and mechanism between eukaryotic topoisomerase I and site-specific recombinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1053%2FPAOR.1999.0209

Topoisomerase I involvement in illegitimate recombination in Saccharomyces cerevisiae

21 January 2018

1 reference

https://api.crossref.org/works/10.1053%2FPAOR.1999.0209

DNA sequence studies of simian virus 40 chromosomal excision and integration in rat cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1053%2FPAOR.1999.0209

International Commission for Protection Against Environmental Mutagens and Carcinogens. Mutagenicity and carcinogenicity of topoisomerase-interactive agents

21 January 2018

1 reference

https://api.crossref.org/works/10.1053%2FPAOR.1999.0209

Cisplatin- and UV-damaged DNA lure the basal transcription factor TFIID/TBP.

21 January 2018

1 reference

https://api.crossref.org/works/10.1053%2FPAOR.1999.0209

Mitotic chromosome condensation in the rDNA requires TRF4 and DNA topoisomerase I in Saccharomyces cerevisiae.

21 January 2018

1 reference

https://api.crossref.org/works/10.1053%2FPAOR.1999.0209

ATP-dependent positive supercoiling of DNA by 13S condensin: a biochemical implication for chromosome condensation

21 January 2018

1 reference

https://api.crossref.org/works/10.1053%2FPAOR.1999.0209

Comparison of biochemical properties of DNA-topoisomerase I from normal and regenerating liver

21 January 2018

1 reference

https://api.crossref.org/works/10.1053%2FPAOR.1999.0209

Cell cycle-specific and transcription-related phosphorylation of mammalian topoisomerase I.

21 January 2018

1 reference

https://api.crossref.org/works/10.1053%2FPAOR.1999.0209

ADP-ribosylation of ADPR-transferase and topoisomerase I in intact mouse epidermal cells JB6.

21 January 2018

1 reference

https://api.crossref.org/works/10.1053%2FPAOR.1999.0209

Poly(ADP-ribose) synthase is the major endogenous nonhistone acceptor for poly(ADP-ribose) in alkylated rat hepatoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1053%2FPAOR.1999.0209

Association of eukaryotic DNA topoisomerase I with nucleosomes and chromosomal proteins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1053%2FPAOR.1999.0209

Association of DNA topoisomerase I and RNA polymerase I: a possible role for topoisomerase I in ribosomal gene transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1053%2FPAOR.1999.0209

Identification of a nucleolin binding site in human topoisomerase I

21 January 2018

1 reference

https://api.crossref.org/works/10.1053%2FPAOR.1999.0209

The interaction between p53 and DNA topoisomerase I is regulated differently in cells with wild-type and mutant p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1053%2FPAOR.1999.0209

Topoisomerase I and II activity in human breast, cervix, lung and colon cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1053%2FPAOR.1999.0209

Variation in topoisomerase I gene copy number as a mechanism for intrinsic drug sensitivity

21 January 2018

1 reference

https://api.crossref.org/works/10.1053%2FPAOR.1999.0209

Modulation of DNA Topoisomerase I Activity byp53

21 January 2018

1 reference

https://api.crossref.org/works/10.1053%2FPAOR.1999.0209

Cellular resistance to topoisomerase-targeted drugs: from drug uptake to cell death

21 January 2018

1 reference

12 December 2020

DNA-topoisomerase I, a new target for the treatment of neuroblastoma

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12 December 2020

Isolation of type I and II DNA topoisomerase mutants from fission yeast: single and double mutants show different phenotypes in cell growth and chromatin organization

1 reference

12 December 2020

Protein kinase C phosphorylates DNA topoisomerase I

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12 December 2020

Structure of the human type I DNA topoisomerase gene

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12 December 2020

Increased synthesis and degradation of DNA topoisomerase I during the initial phase of human T lymphocyte proliferation

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12 December 2020

DNA topoisomerase I controls the kinetics of promoter activation and DNA topology in Saccharomyces cerevisiae

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12 December 2020

Phosphorylation of mammalian DNA topoisomerase I and activation by protein kinase C.

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12 December 2020

The involvement of topoisomerase I in the induction of DNA-protein crosslinks and DNA single-strand breaks in cells of ultraviolet-irradiated human and frog cell lines.

1 reference

12 December 2020

DNA topoisomerases as repair enzymes: mechanism(s) of action and regulation by p53.

1 reference

12 December 2020

Eukaryotic type I topoisomerase is enriched in the nucleolus and catalytically active on ribosomal DNA.

1 reference

12 December 2020

Poly(ADP-ribosylation) of DNA topoisomerase I from calf thymus

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12 December 2020

Poly(ADP-ribosylation) of a DNA topoisomerase

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12 December 2020

DNA topoisomerase I--targeted chemotherapy of human colon cancer in xenografts

1 reference

12 December 2020

Poly(ADP-ribose)-mediated post-translational modification of chromatin-associated human topoisomerase I. Inhibitory effects on catalytic activity

1 reference

12 December 2020

Partial purification of .omega. protein from calf thymus

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12 December 2020

Topoisomerase I phosphorylation in vitro and in rapidly growing Novikoff hepatoma cells

1 reference

12 December 2020

Topoisomerase I-mediated integration of hepadnavirus DNA in vitro

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12 December 2020

Trapping of mammalian topoisomerase I and recombinations induced by damaged DNA containing nicks or gaps. Importance of DNA end phosphorylation and camptothecin effects

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12 December 2020

A type I DNA topoisomerase from Trypanosoma cruzi

1 reference

12 December 2020

Ubiquitin-dependent destruction of topoisomerase I is stimulated by the antitumor drug camptothecin

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12 December 2020

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12 December 2020

Features of two hepatitis B virus (HBV) DNA integrations suggest mechanisms of HBV integration

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12 December 2020

Ultraviolet-induced DNA damage stimulates topoisomerase I-DNA complex formation in vivo: possible relationship with DNA repair

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12 December 2020

Elevation of topoisomerase I messenger RNA, protein, and catalytic activity in human tumors: demonstration of tumor-type specificity and implications for cancer chemotherapy

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12 December 2020

Casein kinase II stimulates Xenopus laevis DNA topoisomerase I by physical association

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12 December 2020

Elevations of DNA topoisomerase I catalytic activity and immunoprotein in human malignancies

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12 December 2020

Changes in topoisomerase I levels and localization during myeloid maturation in vitro and in vivo

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12 December 2020

Down-regulation of topoisomerase I in mammalian cells following ionizing radiation

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12 December 2020

DNA topoisomerase I from calf thymus is inhibited in vitro by poly(ADP-ribosylation)

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12 December 2020

The DNA untwisting enzyme from Saccharomyces cerevisiae. Partial purification and characterization

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12 December 2020

Wild-type and mutant forms of p53 activate human topoisomerase I: a possible mechanism for gain of function in mutants.

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12 December 2020

Expression of DNA topoisomerase I, DNA topoisomerase II-alpha, and p53 in metastatic malignant melanoma

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12 December 2020

Identification of an N-terminal domain of eukaryotic DNA topoisomerase I dispensable for catalytic activity but essential for in vivo function

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12 December 2020

Human DNA topoisomerase I-mediated cleavages stimulated by ultraviolet light-induced DNA damage

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12 December 2020

Regulation of Xenopus laevis DNA topoisomerase I activity by phosphorylation in vitro

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12 December 2020

Identifiers

DOI

10.1053/PAOR.1999.0209

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Dimensions Publication ID

29 July 2017

1006371525

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