(Q33712613)

28 July 2017

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title

Interfacial binding of secreted phospholipases A(2): more than electrostatics and a major role for tryptophan (English)

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28 July 2017

M H Gelb

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28 July 2017

W Cho

series ordinal

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28 July 2017

D C Wilton

series ordinal

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28 July 2017

publication date

1 August 1999

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Current Opinion in Structural Biology

28 July 2017

published in

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28 July 2017

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28 July 2017

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28 July 2017

page(s)

428-432

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Mammalian non-pancreatic phospholipases A2.

28 July 2017

cites work

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Cloning, chromosomal mapping, and expression of a novel human secretory phospholipase A2

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Kinetics of interfacial catalysis by phospholipase A2 in intravesicle scooting mode, and heterofusion of anionic and zwitterionic vesicles

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7 January 2021

Interfacial enzymology of glycerolipid hydrolases: lessons from secreted phospholipases A2.

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Docking phospholipase A2 on membranes using electrostatic potential-modulated spin relaxation magnetic resonance

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7 January 2021

Human non-pancreatic (group II) secreted phospholipase A2 expressed from a synthetic gene in Escherichia coli: characterisation of N-terminal mutants

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7 January 2021

Interfacial recognition by bee venom phospholipase A2: insights into nonelectrostatic molecular determinants by charge reversal mutagenesis

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7 January 2021

Structural aspects of interfacial adsorption. A crystallographic and site-directed mutagenesis study of the phospholipase A2 from the venom of Agkistrodon piscivorus piscivorus

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7 January 2021

The divalent cation is obligatory for the binding of ligands to the catalytic site of secreted phospholipase A2.

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7 January 2021

Active site of bee venom phospholipase A2: the role of histidine-34, aspartate-64 and tyrosine-87.

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7 January 2021

A phospholipase A2 kinetic and binding assay using phospholipid-coated hydrophobic beads

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7 January 2021

Phospholipase A2 at the bilayer interface

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7 January 2021

Modulation of Phospholipase A2: Identification of an Inactive Membrane-Bound State

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7 January 2021

Mapping the interfacial binding surface of human secretory group IIa phospholipase A2.

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Structures of the catalytic site mutants D99A and H48Q and the calcium-loop mutant D49E of phospholipase A2

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7 January 2021

The electrostatic basis for the interfacial binding of secretory phospholipases A2.

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7 January 2021

A structure-function study of bovine pancreatic phospholipase A2 using polymerized mixed liposomes

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7 January 2021

Action of human group IIa secreted phospholipase A2 on cell membranes. Vesicle but not heparinoid binding determines rate of fatty acid release by exogenously added enzyme

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7 January 2021

Use of an imperfect neutral diluent and outer vesicle layer scooting mode hydrolysis to analyze the interfacial kinetics, inhibition, and substrate preferences of bee venom phospholipase A2

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7 January 2021

Interaction of phospholipase A2 and phospholipid bilayers

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7 January 2021

Identification of functional involvement of tryptophan residues in phospholipase A2 from Naja naja atra (Taiwan cobra) snake venom

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7 January 2021

Effects of chemical modifications of Pa-11, a phospholipase A2 from the venom of Australian king brown snake (Pseudechis australis), on its biological activities.

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7 January 2021

Anchoring of tryptophan and tyrosine analogs at the hydrocarbon-polar boundary in model membrane vesicles: parallax analysis of fluorescence quenching induced by nitroxide-labeled phospholipids

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7 January 2021

Tryptophan-containing mutant of human (group IIa) secreted phospholipase A2 has a dramatically increased ability to hydrolyze phosphatidylcholine vesicles and cell membranes

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7 January 2021

Phospholipase A2 engineering. Probing the structural and functional roles of N-terminal residues with site-directed mutagenesis, X-ray, and NMR.

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7 January 2021

Roles of Trp31 in high membrane binding and proinflammatory activity of human group V phospholipase A2

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7 January 2021

Crystal structure of bee-venom phospholipase A2 in a complex with a transition-state analogue

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7 January 2021

10.1016/S0959-440X(99)80059-1

Identifiers

DOI

1 reference

28 July 2017

1 reference