(Q33653389)

28 July 2017

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title

Peptide nucleic acids as therapeutic agents (English)

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28 July 2017

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Nielsen PE

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28 July 2017

publication date

1 June 1999

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Current Opinion in Structural Biology

28 July 2017

published in

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28 July 2017

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28 July 2017

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28 July 2017

page(s)

353-357

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Sequence-selective recognition of DNA by strand displacement with a thymine-substituted polyamide

28 July 2017

cites work

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2899%2980047-5

7 January 2021

DNA unwinding upon strand-displacement binding of a thymine-substituted polyamide to double-stranded DNA.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2899%2980047-5

7 January 2021

Evidence for (PNA)2/DNA triplex structure upon binding of PNA to dsDNA by strand displacement

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2899%2980047-5

7 January 2021

PNA hybridizes to complementary oligonucleotides obeying the Watson–Crick hydrogen-bonding rules

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2899%2980047-5

7 January 2021

Kinetics for hybridization of peptide nucleic acids (PNA) with DNA and RNA studied with the BIAcore technique

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2899%2980047-5

7 January 2021

A formula for thermal stability (Tm) prediction of PNA/DNA duplexes

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2899%2980047-5

7 January 2021

NMR solution structure of a peptide nucleic acid complexed with RNA

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2899%2980047-5

7 January 2021

Solution structure of a peptide nucleic acid-DNA duplex

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2899%2980047-5

7 January 2021

A nucleic acid triple helix formed by a peptide nucleic acid-DNA complex

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2899%2980047-5

7 January 2021

Crystal structure of a peptide nucleic acid (PNA) duplex at 1.7 A resolution

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2899%2980047-5

7 January 2021

Kinetics and mechanism of polyamide ("peptide") nucleic acid binding to duplex DNA.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2899%2980047-5

7 January 2021

Stability of peptide nucleic acids in human serum and cellular extracts

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2899%2980047-5

7 January 2021

Antisense and Antigene Properties of Peptide Nucleic Acids

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2899%2980047-5

7 January 2021

Antisense properties of duplex- and triplex-forming PNAs

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2899%2980047-5

7 January 2021

Additive antisense effects of different PNAs on the in vitro translation of the PML/RARalpha gene

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2899%2980047-5

7 January 2021

Sequence-specific transcription arrest by peptide nucleic acid bound to the DNA template strand

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2899%2980047-5

7 January 2021

Inhibition of NF-κB specific transcriptional activation by PNA strand invasion

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2899%2980047-5

7 January 2021

Peptide nucleic acids directed to the promoter of the alpha-chain of the interleukin-2 receptor

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2899%2980047-5

7 January 2021

Selective inhibition of mutant human mitochondrial DNA replication in vitro by peptide nucleic acids

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2899%2980047-5

7 January 2021

Inhibition of human telomerase activity by peptide nucleic acids

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2899%2980047-5

7 January 2021

Identification of determinants for inhibitor binding within the RNA active site of human telomerase using PNA scanning

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2899%2980047-5

7 January 2021

An assessment of the antisense properties of RNase H-competent and steric-blocking oligomers

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2899%2980047-5

7 January 2021

Cell penetrating PNA constructs regulate galanin receptor levels and modify pain transmission in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2899%2980047-5

7 January 2021

Specific gene blockade shows that peptide nucleic acids readily enter neuronal cells in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2899%2980047-5

7 January 2021

A peptide nucleic acid (PNA) is more rapidly internalized in cultured neurons when coupled to a retro-inverso delivery peptide. The antisense activity depresses the target mRNA and protein in magnocellular oxytocin neurons

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2899%2980047-5

7 January 2021

Antitumor activity of a phosphorothioate antisense oligodeoxynucleotide targeted against C-raf kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2899%2980047-5

7 January 2021

Antisense inhibition of gene expression in bacteria by PNA targeted to mRNA.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2899%2980047-5

7 January 2021

Inhibition of translation and bacterial growth by peptide nucleic acid targeted to ribosomal RNA.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2899%2980047-5

7 January 2021

Efficient in vitro inhibition of HIV-1 gag reverse transcription by peptide nucleic acid (PNA) at minimal ratios of PNA/RNA.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2899%2980047-5

7 January 2021

Polyamide nucleic acid targeted to the primer binding site of the HIV-1 RNA genome blocks in vitro HIV-1 reverse transcription

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2899%2980047-5

7 January 2021

Peptide nucleic acid-targeted mutagenesis of a chromosomal gene in mouse cells

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2899%2980047-5

7 January 2021

Transcription-mediated binding of peptide nucleic acid (PNA) to double-stranded DNA: sequence-specific suicide transcription

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2899%2980047-5

7 January 2021

Enhanced peptide nucleic acid binding to supercoiled DNA: possible implications for DNA "breathing" dynamics

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2899%2980047-5

7 January 2021

Cooperative strand displacement by peptide nucleic acid (PNA).

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2899%2980047-5

7 January 2021

Inhibition of a DNA-helicase by peptide nucleic acids

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2899%2980047-5

7 January 2021

Peptide nucleic acid.DNA strand displacement loops as artificial transcription promoters

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2899%2980047-5

7 January 2021

PNA: Synthetic Polyamide Nucleic Acids with Unusual Binding Properties

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2899%2980047-5

7 January 2021

Synthesis and evaluation of some properties of chimeric oligomers containing PNA and phosphono-PNA residues

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2899%2980047-5

7 January 2021

Optimization of the binding properties of PNA-(5')-DNA chimerae

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2899%2980047-5

7 January 2021

PNA-nucleic acid complexes. Structure, stability and dynamics

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2899%2980047-5

7 January 2021

10.1016/S0959-440X(99)80047-5

Identifiers

DOI

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28 July 2017

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