(Q33536547)

27 July 2017

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title

The Toll-receptor family and control of innate immunity (English)

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27 July 2017

Medzhitov R

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27 July 2017

Kopp EB

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27 July 2017

publication date

1 February 1999

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Current Opinion in Immunology

27 July 2017

published in

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27 July 2017

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27 July 2017

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27 July 2017

page(s)

13-18

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Approaching the asymptote? Evolution and revolution in immunology

27 July 2017

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The cloning and characterization of human MyD88: a member of an IL-1 receptor related family

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Resistance gene-dependent plant defense responses

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Molecular cloning of a human RP105 homologue and chromosomal localization of the mouse and human RP105 genes (Ly64 and LY64).

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Molecular cloning of human RP105

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The molecular mechanism of B cell activation by toll-like receptor protein RP-105

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7 January 2021

The Toll gene of Drosophila, required for dorsal-ventral embryonic polarity, appears to encode a transmembrane protein

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T1/ST2 signaling establishes it as a member of an expanding interleukin-1 receptor family

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The dorsoventral regulatory gene cassette spätzle/Toll/cactus controls the potent antifungal response in Drosophila adults

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The 18-wheeler mutation reveals complex antibacterial gene regulation in Drosophila host defense

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Antimicrobial peptide defense in Drosophila

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Drosophila host defense: differential induction of antimicrobial peptide genes after infection by various classes of microorganisms

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A family of human receptors structurally related to Drosophila Toll

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A human homologue of the Drosophila Toll protein signals activation of adaptive immunity

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7 January 2021

Toll-like receptor-2 mediates lipopolysaccharide-induced cellular signalling

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7 January 2021

A conserved signaling pathway: the Drosophila toll-dorsal pathway

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7 January 2021

Macrophage differentiation marker MyD88 is a member of the Toll/IL-1 receptor family

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MyD88: an adapter that recruits IRAK to the IL-1 receptor complex

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7 January 2021

MyD88 is an adaptor protein in the hToll/IL-1 receptor family signaling pathways

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Targeted disruption of the MyD88 gene results in loss of IL-1- and IL-18-mediated function

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IRAK (Pelle) family member IRAK-2 and MyD88 as proximal mediators of IL-1 signaling

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MyD88, an adapter protein involved in interleukin-1 signaling

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Interleukin (IL)-1 receptor-associated kinase (IRAK) requirement for optimal induction of multiple IL-1 signaling pathways and IL-6 production

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7 January 2021

IRAK: a kinase associated with the interleukin-1 receptor

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7 January 2021

TRAF6 is a signal transducer for interleukin-1

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7 January 2021

The human toll signaling pathway: divergence of nuclear factor kappaB and JNK/SAPK activation upstream of tumor necrosis factor receptor-associated factor 6 (TRAF6)

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A novel family of putative signal transducers associated with the cytoplasmic domain of the 75 kDa tumor necrosis factor receptor

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Identification of TRAF6, a novel tumor necrosis factor receptor-associated factor protein that mediates signaling from an amino-terminal domain of the CD40 cytoplasmic region

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7 January 2021

Tumor necrosis factor (TNF)-mediated kinase cascades: bifurcation of nuclear factor-kappaB and c-jun N-terminal kinase (JNK/SAPK) pathways at TNF receptor-associated factor 2

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7 January 2021

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7 January 2021

Differential regulation of IkappaB kinase alpha and beta by two upstream kinases, NF-kappaB-inducing kinase and mitogen-activated protein kinase/ERK kinase kinase-1

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7 January 2021

NF-kappaB-inducing kinase activates IKK-alpha by phosphorylation of Ser-176

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7 January 2021

The IkappaB kinase complex (IKK) contains two kinase subunits, IKKalpha and IKKbeta, necessary for IkappaB phosphorylation and NF-kappaB activation

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7 January 2021

IkappaB kinase-beta: NF-kappaB activation and complex formation with IkappaB kinase-alpha and NIK

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7 January 2021

IKK-1 and IKK-2: cytokine-activated IkappaB kinases essential for NF-kappaB activation

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7 January 2021

A cytokine-responsive IkappaB kinase that activates the transcription factor NF-kappaB

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7 January 2021

Complementation cloning of NEMO, a component of the IkappaB kinase complex essential for NF-kappaB activation

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7 January 2021

IKAP is a scaffold protein of the IkappaB kinase complex

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7 January 2021

Regulated nuclear import of Rel proteins in the Drosophila immune response

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7 January 2021

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Identifiers

DOI

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27 July 2017

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