(Q33444800)

26 July 2017

title

Abberant alpha-synuclein confers toxicity to neurons in part through inhibition of chaperone-mediated autophagy (English)

1 reference

26 July 2017

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1 reference

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David Park

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Maria Xilouri

1 reference

26 July 2017

Tereza Vogiatzi

series ordinal

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26 July 2017

Kostas Vekrellis

series ordinal

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26 July 2017

Leonidas Stefanis

series ordinal

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26 July 2017

language of work or name

English

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publication date

13 May 2009

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26 July 2017

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26 July 2017

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26 July 2017

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26 July 2017

page(s)

e5515

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Creative Commons Attribution 4.0 International

26 July 2017

start time

13 May 2009

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April 2022 Public Data File from Crossref

copyrighted

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cites work

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Consequences of the selective blockage of chaperone-mediated autophagy

21 June 2018

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Autophagy and signaling: their role in cell survival and cell death

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Lysosomes and autophagy in cell death control

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Alpha-synuclein locus duplication as a cause of familial Parkinson's disease

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Impaired degradation of mutant alpha-synuclein by chaperone-mediated autophagy

21 June 2018

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Mechanisms of chaperone-mediated autophagy

21 June 2018

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Pathophysiology of chaperone-mediated autophagy

21 June 2018

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Neurobiology of alpha-synuclein

21 June 2018

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Autophagy: in sickness and in health

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Parkinson's disease alpha-synuclein mutations exhibit defective axonal transport in cultured neurons

21 June 2018

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21 June 2018

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The new mutation, E46K, of alpha-synuclein causes Parkinson and Lewy body dementia

21 June 2018

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alpha-Synuclein locus triplication causes Parkinson's disease

21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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Staging of brain pathology related to sporadic Parkinson's disease

21 June 2018

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Proteasomal inhibition-induced inclusion formation and death in cortical neurons require transcription and ubiquitination

21 June 2018

1 reference

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alpha -Synucleinopathy and selective dopaminergic neuron loss in a rat lentiviral-based model of Parkinson's disease.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2677735

Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2677735

Alpha-synuclein and Parkinson's disease

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2677735

Neuroprotective actions of dipyridamole on cultured CNS neurons.

21 June 2018

1 reference

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alpha-Synuclein in filamentous inclusions of Lewy bodies from Parkinson's disease and dementia with lewy bodies

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2677735

A simplified system for generating recombinant adenoviruses

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2677735

Ala30Pro mutation in the gene encoding alpha-synuclein in Parkinson's disease

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2677735

Alpha-synuclein in Lewy bodies

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2677735

Mutation in the alpha-synuclein gene identified in families with Parkinson's disease

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2677735

A receptor for the selective uptake and degradation of proteins by lysosomes

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2677735

Age-associated increases of alpha-synuclein in monkeys and humans are associated with nigrostriatal dopamine depletion: Is this the target for Parkinson's disease?

21 June 2018

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https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0005515

α-Synuclein Is Degraded by Both Autophagy and the Proteasome

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0005515

Reversible inhibition of alpha-synuclein fibrillization by dopaminochrome-mediated conformational alterations.

21 January 2018

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https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0005515

Aggregated alpha-synuclein mediates dopaminergic neurotoxicity in vivo.

21 January 2018

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https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0005515

Lack of p53 delays apoptosis, but increases ubiquitinated inclusions, in proteasomal inhibitor-treated cultured cortical neurons

21 January 2018

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https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0005515

Cell-produced alpha-synuclein oligomers are targeted to, and impair, the 26S proteasome

21 January 2018

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Parkinson-like neurodegeneration induced by targeted overexpression of alpha-synuclein in the nigrostriatal system.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2677735

Expression of A53T mutant but not wild-type alpha-synuclein in PC12 cells induces alterations of the ubiquitin-dependent degradation system, loss of dopamine release, and autophagic cell death.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2677735

Caspase-dependent and -independent death of camptothecin-treated embryonic cortical neurons

31 October 2018

1 reference

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Collaborative Analysis of α-Synuclein Gene Promoter Variability and Parkinson Disease

31 October 2018

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Causal relation between alpha-synuclein gene duplication and familial Parkinson's disease

21 January 2018

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12 December 2020

Alpha-synuclein overexpression increases cytosolic catecholamine concentration

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12 December 2020

Inhibitors of trypsin-like serine proteases inhibit processing of the caspase Nedd-2 and protect PC12 cells and sympathetic neurons from death evoked by withdrawal of trophic support

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12 December 2020

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12 December 2020

Multiple agents rescue PC12 cells from serum-free cell death by translation- and transcription-independent mechanisms

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12 December 2020

10.1371/JOURNAL.PONE.0005515

Identifiers

DOI

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26 July 2017

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26 July 2017

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