(Q33283063)

25 July 2017

title

PPAR gamma 2 prevents lipotoxicity by controlling adipose tissue expandability and peripheral lipid metabolism (English)

1 reference

25 July 2017

author

Tuulikki Seppänen-Laakso

object named as

Tuulikki Seppänen-Laakso

0 references

Matej Oresic

0 references

Frances M Ashcroft

1 reference

25 July 2017

Gema Medina-Gomez

1 reference

25 July 2017

Sarah L Gray

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25 July 2017

Laxman Yetukuri

1 reference

25 July 2017

Kenju Shimomura

1 reference

25 July 2017

Sam Virtue

1 reference

25 July 2017

Mark Campbell

1 reference

25 July 2017

R Keira Curtis

1 reference

25 July 2017

Mercedes Jimenez-Linan

1 reference

25 July 2017

Margaret Blount

1 reference

25 July 2017

Giles S H Yeo

1 reference

25 July 2017

Miguel Lopez

1 reference

25 July 2017

Antonio Vidal-Puig

1 reference

25 July 2017

publication date

1 April 2007

1 reference

25 July 2017

1 reference

25 July 2017

1 reference

25 July 2017

1 reference

25 July 2017

page(s)

e64

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Creative Commons Attribution 4.0 International

25 July 2017

start time

27 April 2007

1 reference

April 2022 Public Data File from Crossref

copyrighted

0 references

cites work

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21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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Selective disruption of PPARgamma 2 impairs the development of adipose tissue and insulin sensitivity.

21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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Adipose-specific peroxisome proliferator-activated receptor gamma knockout causes insulin resistance in fat and liver but not in muscle

21 June 2018

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21 June 2018

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Compensation by the muscle limits the metabolic consequences of lipodystrophy in PPAR gamma hypomorphic mice

21 June 2018

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Targeted elimination of peroxisome proliferator-activated receptor gamma in beta cells leads to abnormalities in islet mass without compromising glucose homeostasis

21 June 2018

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21 June 2018

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Muscle-specific PPARgamma-deficient mice develop increased adiposity and insulin resistance but respond to thiazolidinediones

21 June 2018

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21 June 2018

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Liver-specific disruption of PPARgamma in leptin-deficient mice improves fatty liver but aggravates diabetic phenotypes

21 June 2018

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21 June 2018

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21 June 2018

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PPARgamma knockdown by engineered transcription factors: exogenous PPARgamma2 but not PPARgamma1 reactivates adipogenesis

21 June 2018

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CREB regulates hepatic gluconeogenesis through the coactivator PGC-1

21 June 2018

1 reference

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Control of hepatic gluconeogenesis through the transcriptional coactivator PGC-1

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1857730

The role of lipids in the pathogenesis of muscle insulin resistance and beta cell failure in type II diabetes and obesity

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1857730

Molecular regulation of adipogenesis

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1857730

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21 June 2018

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21 June 2018

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PPARγ Is Required for the Differentiation of Adipose Tissue In Vivo and In Vitro

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1857730

PPAR gamma is required for placental, cardiac, and adipose tissue development

21 June 2018

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21 June 2018

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Insulin resistance and diabetes mellitus in transgenic mice expressing nuclear SREBP-1c in adipose tissue: model for congenital generalized lipodystrophy

21 June 2018

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21 June 2018

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PPAR-gamma: adipogenic regulator and thiazolidinedione receptor

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1857730

Peroxisome proliferator-activated receptor gene expression in human tissues. Effects of obesity, weight loss, and regulation by insulin and glucocorticoids

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1857730

Regulation of PPAR gamma gene expression by nutrition and obesity in rodents.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1857730

Differential expression of peroxisome proliferator-activated receptors (PPARs): tissue distribution of PPAR-alpha, -beta, and -gamma in the adult rat

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1857730

Beta-cell lipotoxicity in the pathogenesis of non-insulin-dependent diabetes mellitus of obese rats: impairment in adipocyte-beta-cell relationships

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1857730

The influence of genetic background on the expression of mutations at the diabetes locus in the mouse IV. Male lethal syndrome in CBA/Lt mice

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1857730

Optimizing sampling efficiency of stereological studies in biology: or 'do more less well!'.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1857730

The active synthesis of phosphatidylcholine is required for very low density lipoprotein secretion from rat hepatocytes

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1857730

Energy Expenditure and Fuel Selection in Biological Systems: The Theory and Practice of Calculations Based on Indirect Calorimetry and Tracer Methods

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1857730

Pioglitazone reduces islet triglyceride content and restores impaired glucose-stimulated insulin secretion in heterozygous peroxisome proliferator-activated receptor-gamma-deficient mice on a high-fat diet

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1857730

Lysophosphatidylcholine enhances cytokine production of endothelial cells via induction of L-type amino acid transporter 1 and cell surface antigen 4F2.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1857730

Liver peroxisome proliferator-activated receptor gamma contributes to hepatic steatosis, triglyceride clearance, and regulation of body fat mass.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1857730

N-acetylcysteine and taurine prevent hyperglycemia-induced insulin resistance in vivo: possible role of oxidative stress

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1857730

Role of ATP production and uncoupling protein-2 in the insulin secretory defect induced by chronic exposure to high glucose or free fatty acids and effects of peroxisome proliferator-activated receptor-gamma inhibition

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1857730

Prolonged exposure to free fatty acids has cytostatic and pro-apoptotic effects on human pancreatic islets: evidence that beta-cell death is caspase mediated, partially dependent on ceramide pathway, and Bcl-2 regulated.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1857730

Banting lecture 2001: dysregulation of fatty acid metabolism in the etiology of type 2 diabetes

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1857730

Rat PPARs: quantitative analysis in adult rat tissues and regulation in fasting and refeeding

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1857730

The Pro12 -->Ala substitution in PPAR-gamma is associated with resistance to development of diabetes in the general population: possible involvement in impairment of insulin secretion in individuals with type 2 diabetes

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1857730

Targeted expression of a toxin gene to adipose tissue: transgenic mice resistant to obesity.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1857730

Expression of peroxisome proliferator-activated receptor γ (PPARγ) in normal human pancreatic islet cells

31 October 2018

1 reference

12 December 2020

Genetic typing of the mouse ob mutation by PCR and restriction enzyme analysis

1 reference

12 December 2020

Ligand-independent activation domain in the N terminus of peroxisome proliferator-activated receptor gamma (PPARgamma). Differential activity of PPARgamma1 and -2 isoforms and influence of insulin

1 reference

12 December 2020

Lipotoxicity, an imbalance between lipogenesis de novo and fatty acid oxidation

1 reference

12 December 2020

Diabetes, a New Mutation in the Mouse

1 reference

12 December 2020

10.1371/JOURNAL.PGEN.0030064

Identifiers

DOI

1 reference

25 July 2017

1 reference

25 July 2017

1 reference