(Q33186850)

23 July 2017

title

Mutation of p53 and consecutive selective drug resistance in B-CLL occurs as a consequence of prior DNA-damaging chemotherapy (English)

1 reference

B-cell chronic lymphocytic leukemia

23 July 2017

1 reference

1 reference

1 reference

https://api.crossref.org/works/10.1038/SJ.CDD.4401194

28 December 2023

1 reference

I. Sturm

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12719725

28 December 2023

A. G. Bosanquet

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12719725

28 December 2023

S. Hermann

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12719725

28 December 2023

D. Güner

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12719725

28 December 2023

B. Dörken

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12719725

28 December 2023

P. T. Daniel

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12719725

28 December 2023

language of work or name

English

1 reference

National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=12719725

28 December 2023

publication date

1 April 2003

1 reference

full work available at URL

23 July 2017

https://www.nature.com/articles/4401194.pdf

file format

Portable Document Format

online access status

open access

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12719725

http://www.nature.com/articles/4401194

28 December 2023

1 reference

https://api.crossref.org/works/10.1038/SJ.CDD.4401194

http://www.nature.com/articles/4401194.pdf

28 December 2023

file format

Portable Document Format

1 reference

https://api.crossref.org/works/10.1038/SJ.CDD.4401194

Cell Death & Differentiation

28 December 2023

published in

1 reference

23 July 2017

1 reference

23 July 2017

1 reference

23 July 2017

page(s)

477-484

1 reference

The apoptosis promoting Bcl-2 homologues Bak and Nbk/Bik overcome drug resistance in Mdr-1-negative and Mdr-1-overexpressing breast cancer cell lines

23 July 2017

cites work

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401194

Adenovirus-mediated overexpression of p14(ARF) induces p53 and Bax-independent apoptosis

21 January 2018

1 reference

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Overexpression of caspase-3 restores sensitivity for drug-induced apoptosis in breast cancer cell lines with acquired drug resistance

21 January 2018

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Ceramide induces mitochondrial activation and apoptosis via a Bax-dependent pathway in human carcinoma cells

21 January 2018

1 reference

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Twenty years of p53 research: structural and functional aspects of the p53 protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401194

Relapse in childhood acute lymphoblastic leukemia is associated with a decrease of the Bax/Bcl-2 ratio and loss of spontaneous caspase-3 processing in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401194

The kiss of death: promises and failures of death receptors and ligands in cancer therapy

21 January 2018

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Dissecting the pathways to death

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401194

Bax expression correlates with cellular drug sensitivity to doxorubicin, cyclophosphamide and chlorambucil but not fludarabine, cladribine or corticosteroids in B cell chronic lymphocytic leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401194

Analysis of p53/BAX in primary colorectal carcinoma: low BAX protein expression is a negative prognostic factor in UICC stage III tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401194

Analysis of the p53/BAX pathway in colorectal cancer: low BAX is a negative prognostic factor in patients with resected liver metastases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401194

Impaired BAX protein expression in breast cancer: mutational analysis of the BAX and the p53 gene

21 January 2018

1 reference

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Analysis of p53/BAX/p16(ink4a/CDKN2) in esophageal squamous cell carcinoma: high BAX and p16(ink4a/CDKN2) identifies patients with good prognosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401194

Keeping killers on a tight leash: transcriptional and post-translational control of the pro-apoptotic activity of BH3-only proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401194

Noxa, a BH3-only member of the Bcl-2 family and candidate mediator of p53-induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401194

PUMA, a novel proapoptotic gene, is induced by p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401194

DNA microarray analysis of genes involved in p53 mediated apoptosis: activation of Apaf-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401194

Apaf-1 is a transcriptional target for E2F and p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401194

p53-dependent apoptosis modulates the cytotoxicity of anticancer agents

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401194

p53 mutations in human lymphoid malignancies: association with Burkitt lymphoma and chronic lymphocytic leukemia

21 January 2018

1 reference

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Combined p53/Bax mutation results in extremely poor prognosis in gastric carcinoma with low microsatellite instability

21 January 2018

1 reference

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Multigene analysis of Rb pathway and apoptosis control in esophageal squamous cell carcinoma identifies patients with good prognosis

21 January 2018

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Insights into cancer therapeutic design based on p53 and TRAIL receptor signaling

21 January 2018

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Chlorambucil in indolent chronic lymphocytic leukemia. French Cooperative Group on Chronic Lymphocytic Leukemia

21 January 2018

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The effect of p53 dysfunction on purine analogue cytotoxicity in chronic lymphocytic leukaemia.

21 January 2018

1 reference

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Induction of an apoptotic program in cell-free extracts by 2-chloro-2'-deoxyadenosine 5'-triphosphate and cytochrome c

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401194

Enhanced ex vivo drug sensitivity testing of chronic lymphocytic leukaemia using refined DiSC assay methodology

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401194

Ex vivo assessment of drug response by differential staining cytotoxicity (DiSC) assay suggests a biological basis for equality of chemotherapy irrespective of age for patients with chronic lymphocytic leukaemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401194

7 January 2021

p53-dependent pathways of apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401194

7 January 2021

DNA damage and apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401194

7 January 2021

Radiation-induced apoptosis in the adult central nervous system is p53-dependent

1 reference

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7 January 2021

Chronic lymphocytic leukemia terminating in acute leukemia

1 reference

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7 January 2021

A senescence program controlled by p53 and p16INK4a contributes to the outcome of cancer therapy

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7 January 2021

Exon 5 mutations in the p53 gene in relapsed childhood acute lymphoblastic leukemia

1 reference

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7 January 2021

Loss of normal p53 function confers sensitization to Taxol by increasing G2/M arrest and apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401194

7 January 2021

Taxol-induced mitotic block triggers rapid onset of a p53-independent apoptotic pathway.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401194

7 January 2021

4187

AR Pettitt

2000

1 reference

https://api.crossref.org/works/10.1038/SJ.CDD.4401194

The New England Journal of Medicine

28 December 2023

339

924

HW Grunwald

1998

1 reference

https://api.crossref.org/works/10.1038/SJ.CDD.4401194

28 December 2023

3791

O Brathwaite

1992

1 reference

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28 December 2023

DA Tweddle

2001

1 reference

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28 December 2023

F Morabito

1997

1 reference

https://api.crossref.org/works/10.1038/SJ.CDD.4401194

28 December 2023

Identifiers

1 reference

23 July 2017

1 reference