(Q32063493)

6 July 2017

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title

Recent progress in the biology, chemistry and structural biology of DNA glycosylases (English)

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6 July 2017

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Schärer OD

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6 July 2017

Jiricny J

series ordinal

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6 July 2017

language of work or name

English

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publication date

1 March 2001

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6 July 2017

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6 July 2017

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6 July 2017

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6 July 2017

page(s)

270-281

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Molecular mechanism of nucleotide excision repair.

6 July 2017

cites work

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Instability and decay of the primary structure of DNA

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An N -Glycosidase from Escherichia coli That Releases Free Uracil from DNA Containing Deaminated Cytosine Residues

21 January 2018

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Second pathway for completion of human DNA base excision-repair: reconstitution with purified proteins and requirement for DNase IV (FEN1).

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Mammalian abasic site base excision repair. Identification of the reaction sequence and rate-determining steps

21 January 2018

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Reconstitution of proliferating cell nuclear antigen-dependent repair of apurinic/apyrimidinic sites with purified human proteins

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Excision of deoxyribose phosphate residues by DNA polymerase beta during DNA repair

21 January 2018

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Interaction of human apurinic endonuclease and DNA polymerase beta in the base excision repair pathway

21 January 2018

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Human thymine DNA glycosylase binds to apurinic sites in DNA but is displaced by human apurinic endonuclease 1.

21 January 2018

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DNA-bound structures and mutants reveal abasic DNA binding by APE1 and DNA repair coordination [corrected]

21 January 2018

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Uracil-DNA glycosylase (UNG)-deficient mice reveal a primary role of the enzyme during DNA replication

21 January 2018

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Post-replicative base excision repair in replication foci

21 January 2018

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Identification of a new uracil-DNA glycosylase family by expression cloning using synthetic inhibitors

21 January 2018

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Cloning and expression of human G/T mismatch-specific thymine-DNA glycosylase

21 January 2018

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Mismatch-specific thymine DNA glycosylase and DNA polymerase beta mediate the correction of G.T mispairs in nuclear extracts from human cells

21 January 2018

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A new class of uracil-DNA glycosylases related to human thymine-DNA glycosylase

21 January 2018

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3,N4-ethenocytosine, a highly mutagenic adduct, is a primary substrate for Escherichia coli double-stranded uracil-DNA glycosylase and human mismatch-specific thymine-DNA glycosylase

21 January 2018

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The role of the Escherichia coli mug protein in the removal of uracil and 3,N(4)-ethenocytosine from DNA.

21 January 2018

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Retinoic acid receptors interact physically and functionally with the T:G mismatch-specific thymine-DNA glycosylase

21 January 2018

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5-methylcytosine-DNA glycosylase activity is present in a cloned G/T mismatch DNA glycosylase associated with the chicken embryo DNA demethylation complex

21 January 2018

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The thymine glycosylase MBD4 can bind to the product of deamination at methylated CpG sites

21 January 2018

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The human OGG1 gene: structure, functions, and its implication in the process of carcinogenesis

21 January 2018

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Identification of human MutY homolog (hMYH) as a repair enzyme for 2-hydroxyadenine in DNA and detection of multiple forms of hMYH located in nuclei and mitochondria

21 January 2018

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21 January 2018

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Mutagenesis by 8-oxoguanine: an enemy within

21 January 2018

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Repair of oxidatively damaged guanine in Saccharomyces cerevisiae by an alternative pathway.

21 January 2018

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Cloning and characterization of a functional human homolog of Escherichia coli endonuclease III

21 January 2018

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Cloning and expression of the cDNA encoding the human homologue of the DNA repair enzyme, Escherichia coli endonuclease III

21 January 2018

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Excision of products of oxidative DNA base damage by human NTH1 protein.

21 January 2018

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Saccharomyces cerevisiae Ntg1p and Ntg2p: broad specificity N-glycosylases for the repair of oxidative DNA damage in the nucleus and mitochondria

21 January 2018

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The Saccharomyces cerevisiae homologues of endonuclease III from Escherichia coli, Ntg1 and Ntg2, are both required for efficient repair of spontaneous and induced oxidative DNA damage in yeast

21 January 2018

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3-methyladenine DNA glycosylases: structure, function, and biological importance

21 January 2018

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Nuclear and mitochondrial uracil-DNA glycosylases are generated by alternative splicing and transcription from different positions in the UNG gene

21 January 2018

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Mitochondrial targeting of human DNA glycosylases for repair of oxidative DNA damage

21 January 2018

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Mitochondrial DNA repair pathways.

21 January 2018

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Evidence that MutY and MutM combine to prevent mutations by an oxidatively damaged form of guanine in DNA

21 January 2018

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21 January 2018

Life without DNA repair

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Base excision repair deficient mice lacking the Aag alkyladenine DNA glycosylase.

21 January 2018

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Targeted deletion of alkylpurine-DNA-N-glycosylase in mice eliminates repair of 1,N6-ethenoadenine and hypoxanthine but not of 3,N4-ethenocytosine or 8-oxoguanine

21 January 2018

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Accumulation of premutagenic DNA lesions in mice defective in removal of oxidative base damage

21 January 2018

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Mmh/Ogg1 gene inactivation results in accumulation of 8-hydroxyguanine in mice

21 January 2018

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Database of mouse strains carrying targeted mutations in genes affecting cellular responses to DNA damage. Version 4.

21 January 2018

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The structural basis of specific base-excision repair by uracil-DNA glycosylase

21 January 2018

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Crystal structure and mutational analysis of human uracil-DNA glycosylase: structural basis for specificity and catalysis

21 January 2018

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A nucleotide-flipping mechanism from the structure of human uracil-DNA glycosylase bound to DNA

21 January 2018

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Uracil-DNA glycosylase-DNA substrate and product structures: conformational strain promotes catalytic efficiency by coupled stereoelectronic effects

21 January 2018

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Crystal structure of a G:T/U mismatch-specific DNA glycosylase: mismatch recognition by complementary-strand interactions

21 January 2018

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Crystal structure of a thwarted mismatch glycosylase DNA repair complex

21 January 2018

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Structural basis for recognition and repair of the endogenous mutagen 8-oxoguanine in DNA

21 January 2018

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MutY catalytic core, mutant and bound adenine structures define specificity for DNA repair enzyme superfamily

21 January 2018

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Crystal structure of a human alkylbase-DNA repair enzyme complexed to DNA: mechanisms for nucleotide flipping and base excision

21 January 2018

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Structural basis for the excision repair of alkylation-damaged DNA

21 January 2018

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Three-dimensional structure of a DNA repair enzyme, 3-methyladenine DNA glycosylase II, from Escherichia coli.

21 January 2018

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DNA bending and a flip-out mechanism for base excision by the helix–hairpin–helix DNA glycosylase, Escherichia coli AlkA

21 January 2018

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Atomic model of a pyrimidine dimer excision repair enzyme complexed with a DNA substrate: structural basis for damaged DNA recognition

21 January 2018

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Cloning of a yeast 8-oxoguanine DNA glycosylase reveals the existence of a base-excision DNA-repair protein superfamily

21 January 2018

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Chemical approaches toward understanding base excision DNA repair.

21 January 2018

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DNA containing a chemically reduced apurinic site is a high affinity ligand for the E. coli formamidopyrimidine-DNA glycosylase

21 January 2018

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Specific binding of a designed pyrrolidine abasic site analog to multiple DNA glycosylases

21 January 2018

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AP site structural determinants for Fpg specific recognition

21 January 2018

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Investigation of the mechanisms of DNA binding of the human G/T glycosylase using designed inhibitors

21 January 2018

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Substrate recognition by Escherichia coli MutY using substrate analogs

21 January 2018

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HhaI methyltransferase flips its target base out of the DNA helix

21 January 2018

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The crystal structure of Haelll methyltransferase covalently complexed to DNA: An extrahelical cytosine and rearranged base pairing

21 January 2018

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21 January 2018

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Release of normal bases from intact DNA by a native DNA repair enzyme

21 January 2018

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Generation of a strong mutator phenotype in yeast by imbalanced base excision repair

21 January 2018

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Role of electrophilic and general base catalysis in the mechanism of Escherichia coli uracil DNA glycosylase.

21 January 2018

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Heteronuclear NMR and crystallographic studies of wild-type and H187Q Escherichia coli uracil DNA glycosylase: electrophilic catalysis of uracil expulsion by a neutral histidine 187

21 January 2018

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Separating substrate recognition from base hydrolysis in human thymine DNA glycosylase by mutational analysis

21 January 2018

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Mechanisms of enzymatic glycoside hydrolysis

21 January 2018

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Snapshots along an enzymatic reaction coordinate: analysis of a retaining beta-glycoside hydrolase

21 January 2018

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Molecular basis for discriminating between normal and damaged bases by the human alkyladenine glycosylase, AAG

21 January 2018

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Properties of a Recombinant Human Uracil-DNA Glycosylase from the UNG Gene and Evidence that UNG Encodes the Major Uracil-DNA Glycosylase

21 January 2018

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Mutagenic deamination of cytosine residues in DNA

21 January 2018

1 reference

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10.1002/1521-1878(200103)23:3<270::AID-BIES1037>3.0.CO;2-J

21 January 2018

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DOI

1 reference

6 July 2017

1 reference