(Q31924315)

5 July 2017

title

Opposite effects of the Hsp90 inhibitor Geldanamycin: induction of apoptosis in PC12, and differentiation in N2A cells (English)

1 reference

5 July 2017

J Renart

1 reference

5 July 2017

M D López-Maderuelo

1 reference

5 July 2017

M Fernández-Renart

series ordinal

1 reference

5 July 2017

C Moratilla

series ordinal

1 reference

5 July 2017

language of work or name

English

0 references

publication date

1 February 2001

1 reference

5 July 2017

1 reference

5 July 2017

volume

490

1 reference

5 July 2017

issue

1-2

1 reference

5 July 2017

page(s)

23-27

1 reference

MAP kinase kinase kinase, MAP kinase kinase and MAP kinase

5 July 2017

cites work

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902130-5

Specificity of receptor tyrosine kinase signaling: transient versus sustained extracellular signal-regulated kinase activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902130-5

Sustained activation of the mitogen-activated protein (MAP) kinase cascade may be required for differentiation of PC12 cells. Comparison of the effects of nerve growth factor and epidermal growth factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902130-5

Organization of kinases, phosphatases, and receptor signaling complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902130-5

The role of the hsp90-based chaperone system in signal transduction by nuclear receptors and receptors signaling via MAP kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902130-5

Reduced levels of hsp90 compromise steroid receptor action in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902130-5

A role for Hsp90 in retinoid receptor signal transduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902130-5

Mammalian p50Cdc37 is a protein kinase-targeting subunit of Hsp90 that binds and stabilizes Cdk4

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902130-5

Heat-shock protein hsp90 governs the activity of pp60v-src kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902130-5

Maturation of the tyrosine kinase c-src as a kinase and as a substrate depends on the molecular chaperone Hsp90.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902130-5

Kinase suppressor of Ras forms a multiprotein signaling complex and modulates MEK localization

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902130-5

p50(cdc37) acting in concert with Hsp90 is required for Raf-1 function

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902130-5

Hsp90 as a capacitor for morphological evolution

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902130-5

Protein folding and the regulation of signaling pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902130-5

Destabilization of Raf-1 by geldanamycin leads to disruption of the Raf-1-MEK-mitogen-activated protein kinase signalling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902130-5

Disruption of the Raf-1-Hsp90 Molecular Complex Results in Destabilization of Raf-1 and Loss of Raf-1-Ras Association

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902130-5

Geldanamycin-induced destabilization of Raf-1 involves the proteasome

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902130-5

Nerve growth factor prevents the death and stimulates the neuronal differentiation of clonal PC12 pheochromocytoma cells in serum-free medium

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902130-5

Opposing effects of ERK and JNK-p38 MAP kinases on apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902130-5

A synthetic inhibitor of the mitogen-activated protein kinase cascade

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902130-5

Withdrawal of survival factors results in activation of the JNK pathway in neuronal cells leading to Fas ligand induction and cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902130-5

Aurintricarboxylic acid rescues PC12 cells and sympathetic neurons from cell death caused by nerve growth factor deprivation: correlation with suppression of endonuclease activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902130-5

The hsp90-binding antibiotic geldanamycin decreases Raf levels and epidermal growth factor signaling without disrupting formation of signaling complexes or reducing the specific enzymatic activity of Raf kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902130-5

Nerve growth factor induces survival and differentiation through two distinct signaling cascades in PC12 cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902130-5

A divergence in the MAP kinase regulatory network defined by MEK kinase and Raf

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902130-5

Direct interaction between Ras and the kinase domain of mitogen-activated protein kinase kinase kinase (MEKK1).

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902130-5

Activation of stress-activated protein kinase by MEKK1 phosphorylation of its activator SEK1

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902130-5

Role of SAPK/ERK kinase-1 in the stress-activated pathway regulating transcription factor c-Jun

21 January 2018

2 references

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902130-5

21 January 2018

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902130-5

inferred from DOI database lookup

7 January 2021

based on heuristic

Heat shock proteins and molecular chaperones: mediators of protein conformation and turnover in the cell

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902130-5

Effect of SB 203580 on the activity of c-Raf in vitro and in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902130-5

Depletion of Raf-1 protooncogene by geldanamycin causes apoptosis in human luteinized granulosa cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902130-5

10.1016/S0014-5793(01)02130-5

21 January 2018

Identifiers

DOI

1 reference

5 July 2017

1 reference