(Q31001616)

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Virtual screening of combinatorial libraries across a gene family: in search of inhibitors of Giardia lamblia guanine phosphoribosyltransferase

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

12 September 2017

Virtual screening of combinatorial libraries across a gene family: in search of inhibitors of Giardia lamblia guanine phosphoribosyltransferase (English)

1 reference

Europe PubMed Central

PMC publication ID

12 September 2017

virtual screening

1 reference

based on heuristic

inferred from title

Giardia lamblia

1 reference

based on heuristic

inferred from title

author name string

A M Aronov

1

1 reference

Europe PubMed Central

PMC publication ID

12 September 2017

N R Munagala

2

1 reference

Europe PubMed Central

PMC publication ID

12 September 2017

I D Kuntz

3

1 reference

Europe PubMed Central

PMC publication ID

12 September 2017

C C Wang

4

1 reference

Europe PubMed Central

PMC publication ID

12 September 2017

language of work or name

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publication date

1 September 2001

1 reference

Europe PubMed Central

PMC publication ID

12 September 2017

number of pages

6

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based on heuristic

inferred from page(s)

Antimicrobial Agents and Chemotherapy

1 reference

Europe PubMed Central

PMC publication ID

12 September 2017

45

1 reference

Europe PubMed Central

PMC publication ID

12 September 2017

9

1 reference

Europe PubMed Central

PMC publication ID

12 September 2017

2571-2576

1 reference

Europe PubMed Central

PMC publication ID

12 September 2017

Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings

1 reference

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Adenosine analogues as inhibitors of Trypanosoma brucei phosphoglycerate kinase: elucidation of a novel binding mode for a 2-amino-N(6)-substituted adenosine

1 reference

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Use of an additional hydrophobic binding site, the Z site, in the rational drug design of a new class of stronger trypanothione reductase inhibitor, quaternary alkylammonium phenothiazines

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Crystal structures of Giardia lamblia guanine phosphoribosyltransferase at 1.75 A(,)

1 reference

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21 June 2018

Rational design of selective submicromolar inhibitors of Tritrichomonas foetus hypoxanthine-guanine-xanthine phosphoribosyltransferase

1 reference

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21 June 2018

Structure-based inhibitor design

1 reference

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Crystal structures of the Toxoplasma gondii hypoxanthine-guanine phosphoribosyltransferase-GMP and -IMP complexes: comparison of purine binding interactions with the XMP complex

1 reference

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The 2.0 A structure of malarial purine phosphoribosyltransferase in complex with a transition-state analogue inhibitor

1 reference

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The 2.0 A structure of human hypoxanthine-guanine phosphoribosyltransferase in complex with a transition-state analog inhibitor

1 reference

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21 June 2018

Structure-based design of submicromolar, biologically active inhibitors of trypanosomatid glyceraldehyde-3-phosphate dehydrogenase

1 reference

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21 June 2018

Approaching the transition state in the crystal structure of a phosphoribosyltransferase

1 reference

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Structures of free and complexed forms of Escherichia coli xanthine-guanine phosphoribosyltransferase

1 reference

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Rational design of novel antimicrobials: blocking purine salvage in a parasitic protozoan

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Designer drugs: pipe-dreams or realities?

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Validating targets for antiparasite chemotherapy

1 reference

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Structure-based design of parasitic protease inhibitors

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21 June 2018

Crystal structures of Toxoplasma gondii HGXPRTase reveal the catalytic role of a long flexible loop

1 reference

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21 June 2018

Cloning, expression and characterization of an unusual guanine phosphoribosyltransferase from Giardia lamblia

1 reference

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21 June 2018

Crystal structure of the hypoxanthine-guanine-xanthine phosphoribosyltransferase from the protozoan parasite Tritrichomonas foetus

1 reference

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A flexible loop at the dimer interface is a part of the active site of the adjacent monomer of Escherichia coli orotate phosphoribosyltransferase

1 reference

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Structure-based inhibitor design by using protein models for the development of antiparasitic agents

1 reference

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The crystal structure of human hypoxanthine-guanine phosphoribosyltransferase with bound GMP

1 reference

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21 June 2018

Isolation, sequencing and expression of the gene encoding hypoxanthine-guanine-xanthine phosphoribosyltransferase of Tritrichomonas foetus

1 reference

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The crystal structure of the orotate phosphoribosyltransferase complexed with orotate and alpha-D-5-phosphoribosyl-1-pyrophosphate

1 reference

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Differential inhibitory effects of GMP-2',3'-dialdehyde on human and schistosomal hypoxanthine-guanine phosphoribosyltransferases.

1 reference

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21 June 2018

Purine salvage networks in Giardia lamblia

1 reference

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Parasite enzymes as potential targets for antiparasitic chemotherapy

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Properties and substrate specificity of a purine phosphoribosyltransferase from the human malaria parasite, Plasmodium falciparum

1 reference

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The biology of Giardia spp

1 reference

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21 June 2018

Steady-state kinetics of the schistosomal hypoxanthine-guanine phosphoribosyltransferase

1 reference

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25 November 2018

Identifiers

10.1128/AAC.45.9.2571-2576.2001

1 reference

Europe PubMed Central

PMC publication ID

12 September 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

12 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

12 September 2017

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