(Q30976865)

27 June 2017

title

Dynamic opening of DNA during the enzymatic search for a damaged base (English)

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27 June 2017

Chunyang Cao

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27 June 2017

Yu Lin Jiang

series ordinal

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27 June 2017

James T Stivers

series ordinal

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27 June 2017

Fenhong Song

series ordinal

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27 June 2017

publication date

21 November 2004

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Nature Structural & Molecular Biology

27 June 2017

published in

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27 June 2017

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27 June 2017

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27 June 2017

page(s)

1230-1236

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A mechanistic perspective on the chemistry of DNA repair glycosylases

27 June 2017

cites work

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Site-specific DNA damage recognition by enzyme-induced base flipping

21 January 2018

1 reference

Base excision repair initiation revealed by crystal structures and binding kinetics of human uracil-DNA glycosylase with DNA.

21 January 2018

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Uracil-DNA glycosylase-DNA substrate and product structures: conformational strain promotes catalytic efficiency by coupled stereoelectronic effects

21 January 2018

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Stressing-out DNA? The contribution of serine-phosphodiester interactions in catalysis by uracil DNA glycosylase

21 January 2018

1 reference

Rational Engineering of a DNA Glycosylase Specific for an Unnatural Cytosine:Pyrene Base Pair

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Solution structure and base perturbation studies reveal a novel mode of alkylated base recognition by 3-methyladenine DNA glycosylase I

21 January 2018

1 reference

A nucleotide-flipping mechanism from the structure of human uracil-DNA glycosylase bound to DNA

21 January 2018

1 reference

Crystal structure of a human alkylbase-DNA repair enzyme complexed to DNA: mechanisms for nucleotide flipping and base excision

21 January 2018

1 reference

Molecular basis for discriminating between normal and damaged bases by the human alkyladenine glycosylase, AAG

21 January 2018

1 reference

Mutational analysis of the base-flipping mechanism of uracil DNA glycosylase

21 January 2018

1 reference

Kinetic mechanism of damage site recognition and uracil flipping by Escherichia coli uracil DNA glycosylase

21 January 2018

1 reference

21 January 2018

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Linear free energy correlations for enzymatic base flipping: how do damaged base pairs facilitate specific recognition?

21 January 2018

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Direct visualization of a DNA glycosylase searching for damage

21 January 2018

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How do DNA repair proteins locate damaged bases in the genome?

21 January 2018

1 reference

Role of DNA flexibility in sequence-dependent activity of uracil DNA glycosylase

21 January 2018

1 reference

Free energy and structural pathways of base flipping in a DNA GCGC containing sequence.

21 January 2018

1 reference

Imino proton exchange in DNA catalyzed by ammonia and trimethylamine: evidence for a secondary long-lived open state of the base pair.

21 January 2018

1 reference

Effects of mutations at tyrosine 66 and asparagine 123 in the active site pocket of Escherichia coli uracil DNA glycosylase on uracil excision from synthetic DNA oligomers: evidence for the occurrence of long-range interactions between the enzyme an

21 January 2018

1 reference

Base-flipping mutations of uracil DNA glycosylase: substrate rescue using a pyrene nucleotide wedge

21 January 2018

1 reference

Thermodynamic parameters for DNA sequences with dangling ends

21 January 2018

1 reference

Stereochemical outcome and kinetic effects of Rp- and Sp-phosphorothioate substitutions at the cleavage site of vaccinia type I DNA topoisomerase

21 January 2018

1 reference

Role of electrophilic and general base catalysis in the mechanism of Escherichia coli uracil DNA glycosylase.

21 January 2018

1 reference

Turning On uracil-DNA glycosylase using a pyrene nucleotide switch

21 January 2018

1 reference

Inhibition of uracil DNA glycosylase by an oxacarbenium ion mimic

21 January 2018

1 reference

NMRPipe: a multidimensional spectral processing system based on UNIX pipes

21 January 2018

1 reference

Imino proton exchange and base-pair kinetics in RNA duplexes

21 January 2018

1 reference

Melting of a self-complementary DNA minicircle. Comparison of optical melting theory with exchange broadening of the nuclear magnetic resonance spectrum

21 January 2018

1 reference

A single mode of DNA base-pair opening drives imino proton exchange

21 January 2018

1 reference

Studies of base pair kinetics by NMR measurement of proton exchange

21 January 2018

1 reference

31 March 2020

Identifiers

DOI

10.1038/NSMB864

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27 June 2017

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