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Rapamycin prevents epilepsy in a mouse model of tuberous sclerosis complex.
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1 reference
stated in
Europe PubMed Central
PMC publication ID
3937593
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18389497%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 January 2020
title
Rapamycin prevents epilepsy in a mouse model of tuberous sclerosis complex
(English)
1 reference
stated in
Europe PubMed Central
PMC publication ID
3937593
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18389497%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 January 2020
main subject
tuberous sclerosis
1 reference
based on heuristic
inferred from title
sirolimus
1 reference
based on heuristic
inferred from title
author
David H. Gutmann
series ordinal
3
1 reference
stated in
Europe PubMed Central
PMC publication ID
3937593
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18389497%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 January 2020
author name string
Ling-Hui Zeng
series ordinal
1
1 reference
stated in
Europe PubMed Central
PMC publication ID
3937593
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18389497%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 January 2020
Lin Xu
series ordinal
2
1 reference
stated in
Europe PubMed Central
PMC publication ID
3937593
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18389497%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 January 2020
Michael Wong
series ordinal
4
1 reference
stated in
Europe PubMed Central
PMC publication ID
3937593
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18389497%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 January 2020
publication date
1 April 2008
1 reference
stated in
Europe PubMed Central
PMC publication ID
3937593
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18389497%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 January 2020
published in
Annals of Neurology
1 reference
stated in
Europe PubMed Central
PMC publication ID
3937593
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18389497%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 January 2020
volume
63
1 reference
stated in
Europe PubMed Central
PMC publication ID
3937593
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18389497%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 January 2020
issue
4
1 reference
stated in
Europe PubMed Central
PMC publication ID
3937593
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18389497%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 January 2020
page(s)
444-453
1 reference
stated in
Europe PubMed Central
PMC publication ID
3937593
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18389497%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 January 2020
describes a project that uses
ImageJ
1 reference
stated in
Europe PubMed Central
retrieved
11 June 2022
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3937593/fullTextXML
based on heuristic
inferred from PubMed Central ID database lookup
cites work
Mechanisms of epileptogenesis in tuberous sclerosis complex and related malformations of cortical development with abnormal glioneuronal proliferation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3937593
retrieved
20 June 2018
Abnormal glutamate homeostasis and impaired synaptic plasticity and learning in a mouse model of tuberous sclerosis complex
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3937593
retrieved
20 June 2018
The natural history and treatment of epilepsy in a murine model of tuberous sclerosis.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3937593
retrieved
20 June 2018
Tuberous sclerosis complex and epilepsy: recent developments and future challenges
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3937593
retrieved
20 June 2018
Successive neuron loss in the thalamus and cortex in a mouse model of infantile neuronal ceroid lipofuscinosis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3937593
retrieved
20 June 2018
The tuberous sclerosis complex
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3937593
retrieved
20 June 2018
Antitumoral activity of rapamycin in renal angiomyolipoma associated with tuberous sclerosis complex
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3937593
retrieved
20 June 2018
Rapamycin causes regression of astrocytomas in tuberous sclerosis complex
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3937593
retrieved
20 June 2018
Epileptogenesis and reduced inward rectifier potassium current in tuberous sclerosis complex-1-deficient astrocytes
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3937593
retrieved
20 June 2018
Loss of tuberous sclerosis complex 1 (Tsc1) expression results in increased Rheb/S6K pathway signaling important for astrocyte cell size regulation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3937593
retrieved
20 June 2018
Time-restricted role for dendritic activation of the mTOR-p70 S6K pathway in the induction of late-phase long-term potentiation in the CA1
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3937593
retrieved
20 June 2018
mTor is required for hypertrophy of Pten-deficient neuronal soma in vivo
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3937593
retrieved
20 June 2018
Tuberous sclerosis: from tubers to mTOR.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3937593
retrieved
20 June 2018
Tuberous sclerosis complex-1 and -2 gene products function together to inhibit mammalian target of rapamycin (mTOR)-mediated downstream signaling
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3937593
retrieved
20 June 2018
Tsc tumour suppressor proteins antagonize amino-acid-TOR signalling
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3937593
retrieved
20 June 2018
TSC2 is phosphorylated and inhibited by Akt and suppresses mTOR signalling
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3937593
retrieved
20 June 2018
A rapamycin-sensitive signaling pathway contributes to long-term synaptic plasticity in the hippocampus
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3937593
retrieved
20 June 2018
TSC1 and TSC2 tumor suppressors antagonize insulin signaling in cell growth
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3937593
retrieved
20 June 2018
gigas, a Drosophila homolog of tuberous sclerosis gene product-2, regulates the cell cycle
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3937593
retrieved
20 June 2018
On the incidence of fits and mental retardation in tuberous sclerosis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3937593
retrieved
20 June 2018
Tuberous sclerosis complex: clinical features, diagnosis, and prevalence within Northern Ireland.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3937593
retrieved
26 November 2018
Regulation of astrocytic glutamate transporter expression by Akt: evidence for a selective transcriptional effect on the GLT-1/EAAT2 subtype
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3937593
retrieved
26 November 2018
CNS-directed AAV2-mediated gene therapy ameliorates functional deficits in a murine model of infantile neuronal ceroid lipofuscinosis.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3937593
retrieved
26 November 2018
Efficacy of a rapamycin analog (CCI-779) and IFN-gamma in tuberous sclerosis mouse models
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3937593
retrieved
26 November 2018
Effects of rapamycin in the Eker rat model of tuberous sclerosis complex
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3937593
retrieved
26 November 2018
Impaired glial glutamate transport in a mouse tuberous sclerosis epilepsy model.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3937593
retrieved
26 November 2018
Mutation in TSC2 and activation of mammalian target of rapamycin signalling pathway in renal angiomyolipoma
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3937593
retrieved
26 November 2018
Astrocyte-specific TSC1 conditional knockout mice exhibit abnormal neuronal organization and seizures
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3937593
retrieved
26 November 2018
Drosophila Tsc1 functions with Tsc2 to antagonize insulin signaling in regulating cell growth, cell proliferation, and organ size
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3937593
retrieved
26 November 2018
The Drosophila tuberous sclerosis complex gene homologs restrict cell growth and cell proliferation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3937593
retrieved
26 November 2018
Seizure remission and antiepileptic drug discontinuation in children with tuberous sclerosis complex
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/18389497
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1002/ANA.21331
1 reference
stated in
Europe PubMed Central
PMC publication ID
3937593
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18389497%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 January 2020
Fatcat ID
release_suszt4yg6rbcjoehewsh5lhheq
1 reference
stated in
Fatcat
reference URL
https://api.fatcat.wiki/v0/release/suszt4yg6rbcjoehewsh5lhheq
retrieved
24 November 2022
based on heuristic
mapped directly with Wikidata item
PMC publication ID
3937593
1 reference
stated in
Europe PubMed Central
PMC publication ID
3937593
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18389497%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 January 2020
PubMed publication ID
18389497
1 reference
stated in
Europe PubMed Central
PMC publication ID
3937593
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18389497%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 January 2020
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