(Q30453620)

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Phosphotyrosine (p-Tyr)-dependent and -independent mechanisms of p190 RhoGAP-p120 RasGAP interaction: Tyr 1105 of p190, a substrate for c-Src, is the sole p-Tyr mediator of complex formation

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Europe PubMed Central

PMC publication ID

13 September 2017

Phosphotyrosine (p-Tyr)-dependent and -independent mechanisms of p190 RhoGAP-p120 RasGAP interaction: Tyr 1105 of p190, a substrate for c-Src, is the sole p-Tyr mediator of complex formation (English)

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Europe PubMed Central

PMC publication ID

13 September 2017

Nicholas E. Sherman

4

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Europe PubMed Central

PMC publication ID

13 September 2017

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M Kinter

5

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author name string

R W Roof

1

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Europe PubMed Central

PMC publication ID

13 September 2017

M D Haskell

2

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Europe PubMed Central

PMC publication ID

13 September 2017

B D Dukes

3

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Europe PubMed Central

PMC publication ID

13 September 2017

S J Parsons

6

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Europe PubMed Central

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13 September 2017

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1 December 1998

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Europe PubMed Central

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13 September 2017

Molecular and Cellular Biology

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Europe PubMed Central

PMC publication ID

13 September 2017

18

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Europe PubMed Central

PMC publication ID

13 September 2017

12

1 reference

Europe PubMed Central

PMC publication ID

13 September 2017

7052-7063

1 reference

Europe PubMed Central

PMC publication ID

13 September 2017

The GTPase and Rho GAP domains of p190, a tumor suppressor protein that binds the M(r) 120,000 Ras GAP, independently function as anti-Ras tumor suppressors.

1 reference

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1 reference

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p62, a phosphotyrosine-independent ligand of the SH2 domain of p56lck, belongs to a new class of ubiquitin-binding proteins

1 reference

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20 June 2018

Phosphotyrosine-independent binding of a 62-kDa protein to the src homology 2 (SH2) domain of p56lck and its regulation by phosphorylation of Ser-59 in the lck unique N-terminal region

1 reference

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In vivo association of v-Abl with Shc mediated by a non-phosphotyrosine-dependent SH2 interaction

1 reference

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Monoclonal antibodies to oncoproteins

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The N-terminal region of GAP regulates cytoskeletal structure and cell adhesion

1 reference

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rho family GTPase activating proteins p190, bcr and rhoGAP show distinct specificities in vitro and in vivo

1 reference

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The Ras-related protein Cdc42Hs and bradykinin promote formation of peripheral actin microspikes and filopodia in Swiss 3T3 fibroblasts

1 reference

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20 June 2018

Catalytic specificity of protein-tyrosine kinases is critical for selective signalling

1 reference

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DNA synthesis induced by some but not all growth factors requires Src family protein tyrosine kinases.

1 reference

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20 June 2018

Increased levels of p21ras-GTP and enhanced DNA synthesis accompany elevated tyrosyl phosphorylation of GAP-associated proteins, p190 and p62, in c-src overexpressors

1 reference

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20 June 2018

Tyrosine 807 of the v-Fms oncogene product controls cell morphology and association with p120RasGAP

1 reference

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20 June 2018

Two SH2 Domains of p120 Ras GTPase-activating Protein Bind Synergistically to Tyrosine Phosphorylated p190 Rho GTPase-activating Protein

1 reference

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20 June 2018

Potentiation of epidermal growth factor receptor-mediated oncogenesis by c-Src: implications for the etiology of multiple human cancers

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=109287

20 June 2018

c-Src regulates the simultaneous rearrangement of actin cytoskeleton, p190RhoGAP, and p120RasGAP following epidermal growth factor stimulation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=109287

20 June 2018

Rho, rac, and cdc42 GTPases regulate the assembly of multimolecular focal complexes associated with actin stress fibers, lamellipodia, and filopodia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=109287

20 June 2018

A cyclin-dependent kinase homologue, p130PITSLRE is a phosphotyrosine-independent SH2 ligand

1 reference

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20 June 2018

Raf-1 interacts with Fyn and Src in a non-phosphotyrosine-dependent manner

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=109287

20 June 2018

pp60c-src tyrosine kinase, myristylation, and modulatory domains are required for enhanced mitogenic responsiveness to epidermal growth factor seen in cells overexpressing c-src

1 reference

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20 June 2018

Augmented mitogenic responsiveness to epidermal growth factor in murine fibroblasts that overexpress pp60c-src

1 reference

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20 June 2018

Protein-tyrosine kinases regulate the phosphorylation, protein interactions, subcellular distribution, and activity of p21ras GTPase-activating protein

1 reference

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20 June 2018

Phosphopeptide mapping and phosphoamino acid analysis by two-dimensional separation on thin-layer cellulose plates

1 reference

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20 June 2018

Comparative analysis of signaling pathways between mast cell growth factor (c-kit ligand) and granulocyte-macrophage colony-stimulating factor in a human factor-dependent myeloid cell line involves phosphorylation of Raf-1, GTPase-activating [...]

1 reference

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20 June 2018

BCR sequences essential for transformation by the BCR-ABL oncogene bind to the ABL SH2 regulatory domain in a non-phosphotyrosine-dependent manner

1 reference

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20 June 2018

Transformation by pp60src or stimulation of cells with epidermal growth factor induces the stable association of tyrosine-phosphorylated cellular proteins with GTPase-activating protein

1 reference

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Phosphorylation of GAP and GAP-associated proteins by transforming and mitogenic tyrosine kinases

1 reference

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20 June 2018

The small GTP-binding protein rac regulates growth factor-induced membrane ruffling

1 reference

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The small GTP-binding protein rho regulates the assembly of focal adhesions and actin stress fibers in response to growth factors

1 reference

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20 June 2018

Molecular cloning of cDNAs encoding the GAP-associated protein p190: implications for a signaling pathway from ras to the nucleus

1 reference

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20 June 2018

Multiple SH2-mediated interactions in v-src-transformed cells

1 reference

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Association between GTPase activators for Rho and Ras families.

1 reference

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20 June 2018

A limited set of SH2 domains binds BCR through a high-affinity phosphotyrosine-independent interaction

1 reference

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20 June 2018

Identifiers

10.1128/MCB.18.12.7052

1 reference

Europe PubMed Central

PMC publication ID

13 September 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

13 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

13 September 2017

ResearchGate publication ID

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