(Q30010164)

21 May 2017

title

PIKE mediates EGFR proliferative signaling in squamous cell carcinoma cells (English)

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21 May 2017

Z Xie

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21 May 2017

Y Jiang

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21 May 2017

E-Y Liao

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21 May 2017

Y Chen

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21 May 2017

S D Pennypacker

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21 May 2017

J Peng

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21 May 2017

S M Chang

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21 May 2017

language of work or name

English

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publication date

20 February 2012

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21 May 2017

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21 May 2017

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21 May 2017

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21 May 2017

page(s)

5090-5098

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Overexpression of EGFR and absence of C-KIT expression correlate with poor prognosis in salivary gland carcinomas

21 May 2017

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The mechanism of phospholipase C-gamma1 regulation

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Activation of phospholipase C gamma by PI 3-kinase-induced PH domain-mediated membrane targeting.

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Protein kinase C alpha activates RAF-1 by direct phosphorylation

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Protein kinase C activates the MEK-ERK pathway in a manner independent of Ras and dependent on Raf.

21 January 2018

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Role of diacylglycerol-regulated protein kinase C isotypes in growth factor activation of the Raf-1 protein kinase

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Epidermal growth factor signaling and mitogenesis in Plcg1 null mouse embryonic fibroblasts

21 January 2018

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Epidermal growth factor receptor-mediated cell motility: phospholipase C activity is required, but mitogen-activated protein kinase activity is not sufficient for induced cell movement

21 January 2018

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PLC gamma 1 Src homology domain induces mitogenesis in quiescent NIH 3T3 fibroblasts

21 January 2018

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An SH3 domain is required for the mitogenic activity of microinjected phospholipase C-gamma 1.

21 January 2018

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Requirement for phospholipase C-gamma1 enzymatic activity in growth factor-induced mitogenesis

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Phospholipase C-gamma1 is required for the epidermal growth factor receptor-induced squamous cell carcinoma cell mitogenesis

21 January 2018

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The SH3 domain, but not the catalytic domain, is required for phospholipase C-gamma1 to mediate epidermal growth factor-induced mitogenesis

21 January 2018

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Phospholipase C gamma 1 is a physiological guanine nucleotide exchange factor for the nuclear GTPase PIKE

21 January 2018

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Pike. A nuclear gtpase that enhances PI3kinase activity and is regulated by protein 4.1N

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Nucleolin is a protein kinase C-zeta substrate. Connection between cell surface signaling and nucleus in PC12 cells

21 January 2018

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PIKE-A is amplified in human cancers and prevents apoptosis by up-regulating Akt

21 January 2018

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PIKE-A is a proto-oncogene promoting cell growth, transformation and invasion

21 January 2018

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Involvement of phosphatidylinositol 3-kinase in nuclear translocation of protein kinase C zeta induced by C2-ceramide in rat hepatocytes

21 January 2018

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Nucleolin: The most abundant multifunctional phosphoprotein of nucleolus

21 January 2018

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21 January 2018

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21 January 2018

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The recruitment of phosphatidylinositol 3-kinase to the E-cadherin-catenin complex at the plasma membrane is required for calcium-induced phospholipase C-gamma1 activation and human keratinocyte differentiation.

21 January 2018

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21 January 2018

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Calcium-induced human keratinocyte differentiation requires src- and fyn-mediated phosphatidylinositol 3-kinase-dependent activation of phospholipase C-gamma1

21 January 2018

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Immunohistochemical expression of EGFR and p-EGFR in oral squamous cell carcinomas

21 January 2018

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EGFR protein overexpression and gene amplification in squamous cell carcinomas of the esophagus

31 March 2020

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EGFR overexpression in malignant pleural mesothelioma

31 March 2020

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EGFR gene copy number alterations in primary cutaneous malignant melanomas are associated with poor prognosis

31 March 2020

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Epidermal growth factor receptor (EGFR) expression is associated with a worse prognosis in gastric cancer patients undergoing curative surgery

31 March 2020

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Protein kinase C, but not tyrosine kinases or Ras, plays a critical role in angiotensin II-induced activation of Raf-1 kinase and extracellular signal-regulated protein kinases in cardiac myocytes

31 March 2020

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Nuclear translocation of PKC zeta during ischemia and its inhibition by wortmannin, an inhibitor of phosphatidylinositol 3-kinase

31 March 2020

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Increase in nuclear phosphatidylinositol 3-kinase activity and phosphatidylinositol (3,4,5) trisphosphate synthesis precede PKC-zeta translocation to the nucleus of NGF-treated PC12 cells

31 March 2020

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