(Q29812273)

E3 ubiquitin-protein ligase SIN-like

1 reference

Zinc finger, RING/FYVE/PHD-type

1 reference

Seven-in-absentia protein, TRAF-like domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Zinc finger, RING-type, protein family

1 reference

based on heuristic

inferred from protein domain or family

Zinc finger, SIAH-type, protein family

1 reference

based on heuristic

inferred from protein domain or family

found in taxon

Drosophila melanogaster

1 reference

25 May 2022

1 reference

25 May 2022

ubiquitin-protein transferase activity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21461

1 reference

8 April 2019

ISS

protein binding

7 references

8 April 2019

PHYL acts to down-regulate TTK88, a transcriptional repressor of neuronal cell fates, by a SINA-dependent mechanism.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21461

8 April 2019

A role for Ebi in neuronal cell cycle control

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21461

8 April 2019

PHYL acts to down-regulate TTK88, a transcriptional repressor of neuronal cell fates, by a SINA-dependent mechanism.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21461

8 April 2019

A protein interaction map of Drosophila melanogaster

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21461

8 April 2019

Phyllopod acts as an adaptor protein to link the sina ubiquitin ligase to the substrate protein tramtrack

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21461

8 April 2019

A role for Ebi in neuronal cell cycle control

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21461

8 April 2019

PHYL acts to down-regulate TTK88, a transcriptional repressor of neuronal cell fates, by a SINA-dependent mechanism.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21461

transferase activity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21461

1 reference

8 April 2019

identical protein binding

protein self-association

1 reference

27 March 2018

Phyllopod acts as an adaptor protein to link the sina ubiquitin ligase to the substrate protein tramtrack

http://www.ebi.ac.uk/QuickGO/annotations?protein=P21461&geneProductId=UniProtKB:P21461

metal ion binding

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21461

1 reference

8 April 2019

ubiquitin conjugating enzyme binding

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21461

ubiquitin protein ligase activity

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21461

cell component

ubiquitin ligase complex

1 reference

8 April 2019

Phyllopod acts as an adaptor protein to link the sina ubiquitin ligase to the substrate protein tramtrack

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21461

nucleus

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21461

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21461

8 April 2019

8 April 2019

seven in absentia, a gene required for specification of R7 cell fate in the Drosophila eye.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21461

cytoplasm

http://www.ebi.ac.uk/QuickGO/annotations?protein=P21461&geneProductId=UniProtKB:P21461

3 references

27 March 2018

27 March 2018

seven in absentia, a gene required for specification of R7 cell fate in the Drosophila eye.

http://www.ebi.ac.uk/QuickGO/annotations?protein=P21461&geneProductId=UniProtKB:P21461

27 March 2018

Mammalian homologs of seven in absentia regulate DCC via the ubiquitin-proteasome pathway

http://www.ebi.ac.uk/QuickGO/annotations?protein=P21461&geneProductId=UniProtKB:P21461

cytoplasm

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21461

1 reference

8 April 2019

biological process

proteolysis

TAS

1 reference

27 March 2018

Control of protein degradation by E3 ubiquitin ligases in Drosophila eye development.

http://www.ebi.ac.uk/QuickGO/annotations?protein=P21461&geneProductId=UniProtKB:P21461

sensory organ development

TAS

1 reference

8 April 2019

A dual function of phyllopod in Drosophila external sensory organ development: cell fate specification of sensory organ precursor and its progeny.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21461

visual perception

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21461

1 reference

8 April 2019

proteasomal protein catabolic process

1 reference

8 April 2019

Two modes of degradation of the tramtrack transcription factors by Siah homologues

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21461

protein ubiquitination

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21461

1 reference

8 April 2019

regulation of R7 cell differentiation

1 reference

8 April 2019

seven in absentia, a gene required for specification of R7 cell fate in the Drosophila eye.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21461

response to stimulus

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21461

1 reference

8 April 2019

enteroendocrine cell differentiation

1 reference

8 April 2019

A Phyllopod-Mediated Feedback Loop Promotes Intestinal Stem Cell Enteroendocrine Commitment in Drosophila

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21461

R7 cell fate commitment

Identification of genes that interact with the sina gene in Drosophila eye development

4 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21461

8 April 2019

Phyllopod acts as an adaptor protein to link the sina ubiquitin ligase to the substrate protein tramtrack

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21461

8 April 2019

Musashi and seven in absentia downregulate Tramtrack through distinct mechanisms in Drosophila eye development.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21461

8 April 2019

PHYL acts to down-regulate TTK88, a transcriptional repressor of neuronal cell fates, by a SINA-dependent mechanism.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21461

positive regulation of proteasomal ubiquitin-dependent protein catabolic process

1 reference

8 April 2019

Phyllopod acts as an adaptor protein to link the sina ubiquitin ligase to the substrate protein tramtrack

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21461

proteasome-mediated ubiquitin-dependent protein catabolic process

1 reference

16 July 2018

Photoreceptor cell differentiation requires regulated proteolysis of the transcriptional repressor Tramtrack.

http://www.ebi.ac.uk/QuickGO/annotations?protein=P21461&geneProductId=UniProtKB:P21461

sevenless signaling pathway

3 references

8 April 2019

Identification of genes that interact with the sina gene in Drosophila eye development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21461

8 April 2019

Photoreceptor cell differentiation requires regulated proteolysis of the transcriptional repressor Tramtrack.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21461

8 April 2019

Prepattern in the developing Drosophila eye revealed by an activated torso--sevenless chimeric receptor

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21461

ubiquitin-dependent protein catabolic process

Mammalian homologs of seven in absentia regulate DCC via the ubiquitin-proteasome pathway

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21461

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21461

8 April 2019

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21461

proteasome-mediated ubiquitin-dependent protein catabolic process

has part(s)

Zinc finger, SIAH-type

1 reference

Seven-in-absentia protein, TRAF-like domain

1 reference

Zinc finger, RING-type

1 reference