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English
Linking colorectal cancer to Wnt signaling
scientific article (publication date: 13 October 2000)
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review article
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Europe PubMed Central
title
Linking colorectal cancer to Wnt signaling
(English)
1 reference
stated in
PubMed
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=11057903
retrieved
30 April 2017
main subject
colorectal cancer
1 reference
based on heuristic
inferred from title
colorectal carcinoma
1 reference
based on heuristic
inferred from title
author name string
Bienz M
series ordinal
1
1 reference
stated in
PubMed
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=11057903
retrieved
30 April 2017
Clevers H
series ordinal
2
1 reference
stated in
PubMed
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=11057903
retrieved
30 April 2017
language of work or name
English
1 reference
stated in
PubMed
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=11057903
retrieved
30 April 2017
publication date
13 October 2000
1 reference
stated in
PubMed
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=11057903
retrieved
30 April 2017
published in
Cell
1 reference
stated in
PubMed
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=11057903
retrieved
30 April 2017
volume
103
1 reference
stated in
PubMed
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=11057903
retrieved
30 April 2017
issue
2
1 reference
stated in
PubMed
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=11057903
retrieved
30 April 2017
page(s)
311-20
1 reference
stated in
PubMed
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=11057903
retrieved
30 April 2017
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beta-catenin regulates the expression of the matrix metalloproteinase-7 in human colorectal cancer
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Binding to cadherins antagonizes the signaling activity of beta-catenin during axis formation in Xenopus
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Interaction among GSK-3, GBP, axin, and APC in Xenopus axis specification
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De Novo hair follicle morphogenesis and hair tumors in mice expressing a truncated beta-catenin in skin
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LEF-1 contains an activation domain that stimulates transcription only in a specific context of factor-binding sites.
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Identification and characterization of E-APC, a novel Drosophila homologue of the tumour suppressor APC.
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Intestinal polyposis in mice with a dominant stable mutation of the beta-catenin gene
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Downregulation of beta-catenin by human Axin and its association with the APC tumor suppressor, beta-catenin and GSK3 beta
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A Drosophila homolog of the tumor suppressor gene adenomatous polyposis coli down-regulates beta-catenin but its zygotic expression is not essential for the regulation of Armadillo
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Identification of c-MYC as a target of the APC pathway
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PPARdelta is an APC-regulated target of nonsteroidal anti-inflammatory drugs
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The p300/CBP acetyltransferases function as transcriptional coactivators of beta-catenin in vertebrates
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Nuclear-cytoplasmic shuttling of APC regulates beta-catenin subcellular localization and turnover
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Tumor-suppressor gene products in cell contacts: the cadherin-APC-armadillo connection
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Axin, a negative regulator of the Wnt signaling pathway, forms a complex with GSK-3beta and beta-catenin and promotes GSK-3beta-dependent phosphorylation of beta-catenin
1 reference
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7 January 2021
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Regulation of the Hedgehog and Wingless signalling pathways by the F-box/WD40-repeat protein Slimb
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7 January 2021
based on heuristic
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Asef, a link between the tumor suppressor APC and G-protein signaling
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7 January 2021
based on heuristic
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Lessons from hereditary colorectal cancer
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7 January 2021
based on heuristic
inferred from DOI database lookup
Identification of FAP locus genes from chromosome 5q21
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7 January 2021
based on heuristic
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DIX domains of Dvl and axin are necessary for protein interactions and their ability to regulate beta-catenin stability
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900122-7
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7 January 2021
based on heuristic
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Axin prevents Wnt-3a-induced accumulation of beta-catenin
1 reference
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Crossref
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https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900122-7
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7 January 2021
based on heuristic
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Constitutive transcriptional activation by a beta-catenin-Tcf complex in APC-/- colon carcinoma
1 reference
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Crossref
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7 January 2021
based on heuristic
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Depletion of epithelial stem-cell compartments in the small intestine of mice lacking Tcf-4
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Crossref
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7 January 2021
based on heuristic
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Distinct beta-catenins mediate adhesion and signalling functions in C. elegans
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7 January 2021
based on heuristic
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Familial adenomatous polyposis
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7 January 2021
based on heuristic
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APC mutations are sufficient for the growth of early colorectal adenomas
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900122-7
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7 January 2021
based on heuristic
inferred from DOI database lookup
beta-TrCP is a negative regulator of Wnt/beta-catenin signaling pathway and dorsal axis formation in Xenopus embryos.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900122-7
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7 January 2021
based on heuristic
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Inactivation of the type II TGF-beta receptor in colon cancer cells with microsatellite instability
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900122-7
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7 January 2021
based on heuristic
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Binding of APC to the human homolog of the Drosophila discs large tumor suppressor protein.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900122-7
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7 January 2021
based on heuristic
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Drosophila APC2 is a cytoskeletally-associated protein that regulates wingless signaling in the embryonic epidermis
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900122-7
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7 January 2021
based on heuristic
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Polyclonal structure of intestinal adenomas in ApcMin/+ mice with concomitant loss of Apc+ from all tumor lineages
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900122-7
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7 January 2021
based on heuristic
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Signal transduction through beta-catenin and specification of cell fate during embryogenesis
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900122-7
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7 January 2021
based on heuristic
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Adenomatous polyposis coli (APC) protein moves along microtubules and concentrates at their growing ends in epithelial cells
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900122-7
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7 January 2021
based on heuristic
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XTcf-3 transcription factor mediates beta-catenin-induced axis formation in Xenopus embryos
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900122-7
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7 January 2021
based on heuristic
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Activation of beta-catenin-Tcf signaling in colon cancer by mutations in beta-catenin or APC
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900122-7
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7 January 2021
based on heuristic
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Regulation of intracellular beta-catenin levels by the adenomatous polyposis coli (APC) tumor-suppressor protein
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900122-7
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7 January 2021
based on heuristic
inferred from DOI database lookup
Mutations of the APC (adenomatous polyposis coli) gene
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900122-7
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7 January 2021
based on heuristic
inferred from DOI database lookup
The adenomatous polyposis coli tumor suppressor protein localizes to plasma membrane sites involved in active cell migration.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900122-7
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7 January 2021
based on heuristic
inferred from DOI database lookup
dishevelled and armadillo act in the wingless signalling pathway in Drosophila
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900122-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
An in vivo structure-function study of armadillo, the beta-catenin homologue, reveals both separate and overlapping regions of the protein required for cell adhesion and for wingless signaling
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900122-7
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7 January 2021
based on heuristic
inferred from DOI database lookup
Loss of Apc heterozygosity and abnormal tissue building in nascent intestinal polyps in mice carrying a truncated Apc gene
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900122-7
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7 January 2021
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The genetic basis of patterned baldness in Drosophila
1 reference
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https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900122-7
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7 January 2021
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LEF-1, a nuclear factor coordinating signaling inputs from wingless and decapentaplegic.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900122-7
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7 January 2021
based on heuristic
inferred from DOI database lookup
Mad-related genes in the human
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900122-7
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7 January 2021
based on heuristic
inferred from DOI database lookup
Wnt signaling and an APC-related gene specify endoderm in early C. elegans embryos
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900122-7
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7 January 2021
based on heuristic
inferred from DOI database lookup
The Xenopus Wnt effector XTcf-3 interacts with Groucho-related transcriptional repressors
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900122-7
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7 January 2021
based on heuristic
inferred from DOI database lookup
Synergy between tumor suppressor APC and the beta-catenin-Tcf4 target Tcf1.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900122-7
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7 January 2021
based on heuristic
inferred from DOI database lookup
The APC tumour suppressor has a nuclear export function.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900122-7
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7 January 2021
based on heuristic
inferred from DOI database lookup
Association of the APC gene product with beta-catenin
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900122-7
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7 January 2021
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Stabilization of beta-catenin by genetic defects in melanoma cell lines
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900122-7
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7 January 2021
based on heuristic
inferred from DOI database lookup
Uncoupling cadherin-based adhesion from wingless signalling in Drosophila.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900122-7
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7 January 2021
based on heuristic
inferred from DOI database lookup
AXIN1 mutations in hepatocellular carcinomas, and growth suppression in cancer cells by virus-mediated transfer of AXIN1
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900122-7
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7 January 2021
based on heuristic
inferred from DOI database lookup
wingless signaling acts through zeste-white 3, the Drosophila homolog of glycogen synthase kinase-3, to regulate engrailed and establish cell fate
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900122-7
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7 January 2021
based on heuristic
inferred from DOI database lookup
Components of wingless signalling in Drosophila.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900122-7
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7 January 2021
based on heuristic
inferred from DOI database lookup
Interaction of axin and Dvl-2 proteins regulates Dvl-2-stimulated TCF-dependent transcription.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900122-7
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7 January 2021
based on heuristic
inferred from DOI database lookup
Loss of Apc and the entire chromosome 18 but absence of mutations at the Ras and Tp53 genes in intestinal tumors from Apc1638N, a mouse model for Apc-driven carcinogenesis.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900122-7
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7 January 2021
based on heuristic
inferred from DOI database lookup
Apc1638T: a mouse model delineating critical domains of the adenomatous polyposis coli protein involved in tumorigenesis and development
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900122-7
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7 January 2021
based on heuristic
inferred from DOI database lookup
Intestinal tumorigenesis in compound mutant mice of both Dpc4 (Smad4) and Apc genes
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900122-7
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7 January 2021
based on heuristic
inferred from DOI database lookup
The transcriptional coactivator CBP interacts with beta-catenin to activate gene expression
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900122-7
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7 January 2021
based on heuristic
inferred from DOI database lookup
Beta-catenin regulates expression of cyclin D1 in colon carcinoma cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900122-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Wnt signaling polarizes an early C. elegans blastomere to distinguish endoderm from mesoderm
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900122-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Armadillo coactivates transcription driven by the product of the Drosophila segment polarity gene dTCF
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900122-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identification of APC2, a homologue of the adenomatous polyposis coli tumour suppressor
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900122-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Hot spots in beta-catenin for interactions with LEF-1, conductin and APC
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900122-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Drosophila CBP represses the transcription factor TCF to antagonize Wingless signalling.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900122-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Intestinal tumorigenesis is suppressed in mice lacking the metalloproteinase matrilysin
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900122-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Dlg protein is required for junction structure, cell polarity, and proliferation control in Drosophila epithelia
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900122-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
beta-catenin can be transported into the nucleus in a Ran-unassisted manner
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900122-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
GBP, an inhibitor of GSK-3, is implicated in Xenopus development and oncogenesis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900122-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Ubiquitous expression of a Drosophila adenomatous polyposis coli homolog and its localization in cortical actin caps
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900122-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A new Drosophila APC homologue associated with adhesive zones of epithelial cells.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900122-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The mouse Fused locus encodes Axin, an inhibitor of the Wnt signaling pathway that regulates embryonic axis formation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900122-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1016/S0092-8674(00)00122-7
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
1315279
OpenCitations bibliographic resource ID
1315279
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
1315279
PubMed publication ID
11057903
2 references
stated in
PubMed
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=11057903
retrieved
30 April 2017
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
1315279
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