(Q29617806)

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=15122348

30 April 2017

1 reference

0 references

Ratcliffe PJ

0 references

Schofield CJ

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=15122348

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=15122348

30 April 2017

language of work or name

1 reference

30 April 2017

publication date

May 2004

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=15122348

Nature Reviews Molecular Cell Biology

30 April 2017

published in

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=15122348

30 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=15122348

30 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=15122348

30 April 2017

page(s)

343-54

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=15122348

A nuclear factor induced by hypoxia via de novo protein synthesis binds to the human erythropoietin gene enhancer at a site required for transcriptional activation

30 April 2017

cites work

1 reference

Inducible operation of the erythropoietin 3' enhancer in multiple cell lines: evidence for a widespread oxygen-sensing mechanism

31 March 2020

1 reference

Hypoxia-inducible factor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular O2 tension

31 March 2020

1 reference

Hypoxia-inducible factor 1: oxygen homeostasis and disease pathophysiology

31 March 2020

1 reference

Cellular adaptation to hypoxia: O2-sensing protein hydroxylases, hypoxia-inducible transcription factors, and O2-regulated gene expression

31 March 2020

1 reference

Regulation of angiogenesis by hypoxia: role of the HIF system

31 March 2020

1 reference

Hypoxia-inducible factor and its biomedical relevance

31 March 2020

1 reference

Targeting HIF-1 for cancer therapy

31 March 2020

1 reference

HIF prolyl and asparaginyl hydroxylases in the biological response to intracellular O(2) levels

31 March 2020

1 reference

Multiple splice variants of the human HIF-3 alpha locus are targets of the von Hippel-Lindau E3 ubiquitin ligase complex

31 March 2020

1 reference

Inhibitory PAS domain protein is a negative regulator of hypoxia-inducible gene expression

31 March 2020

1 reference

HIFalpha targeted for VHL-mediated destruction by proline hydroxylation: implications for O2 sensing

31 March 2020

1 reference

Targeting of HIF-alpha to the von Hippel-Lindau ubiquitylation complex by O2-regulated prolyl hydroxylation

31 March 2020

1 reference

HIF-1alpha binding to VHL is regulated by stimulus-sensitive proline hydroxylation

31 March 2020

1 reference

Independent function of two destruction domains in hypoxia-inducible factor-alpha chains activated by prolyl hydroxylation

31 March 2020

1 reference

The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis

31 March 2020

1 reference

Ubiquitination of hypoxia-inducible factor requires direct binding to the beta-domain of the von Hippel-Lindau protein

31 March 2020

1 reference

Structural basis for the recognition of hydroxyproline in HIF-1 alpha by pVHL

31 March 2020

1 reference

Structure of an HIF-1alpha -pVHL complex: hydroxyproline recognition in signaling

31 March 2020

1 reference

C. elegans EGL-9 and mammalian homologs define a family of dioxygenases that regulate HIF by prolyl hydroxylation

31 March 2020

1 reference

A conserved family of prolyl-4-hydroxylases that modify HIF

31 March 2020

1 reference

Asparagine hydroxylation of the HIF transactivation domain a hypoxic switch

31 March 2020

1 reference

Hypoxia-inducible factor asparaginyl hydroxylase (FIH-1) catalyses hydroxylation at the beta-carbon of asparagine-803

31 March 2020

1 reference

Structural basis for recruitment of CBP/p300 by hypoxia-inducible factor-1 alpha

31 March 2020

1 reference

Structural basis for Hif-1 alpha /CBP recognition in the cellular hypoxic response

31 March 2020

1 reference

FIH-1 is an asparaginyl hydroxylase enzyme that regulates the transcriptional activity of hypoxia-inducible factor

31 March 2020

1 reference

Hypoxia-inducible factor (HIF) asparagine hydroxylase is identical to factor inhibiting HIF (FIH) and is related to the cupin structural family

31 March 2020

1 reference

FIH-1: a novel protein that interacts with HIF-1alpha and VHL to mediate repression of HIF-1 transcriptional activity

31 March 2020

1 reference

Control of the hypoxic response in Drosophila melanogaster by the basic helix-loop-helix PAS protein similar.

31 March 2020

1 reference

HIF prolyl-hydroxylase 2 is the key oxygen sensor setting low steady-state levels of HIF-1alpha in normoxia

31 March 2020

1 reference

Structural and mechanistic studies on 2-oxoglutarate-dependent oxygenases and related enzymes

31 March 2020

1 reference

The 2-His-1-carboxylate facial triad--an emerging structural motif in mononuclear non-heme iron(II) enzymes

31 March 2020

1 reference

The DNA-repair protein AlkB, EGL-9, and leprecan define new families of 2-oxoglutarate- and iron-dependent dioxygenases

31 March 2020

1 reference

Structure of a cephalosporin synthase

31 March 2020

1 reference

Kinetic and crystallographic studies on deacetoxycephalosporin C synthase (DAOCS)

31 March 2020

1 reference

Crystal structure of isopenicillin N synthase is the first from a new structural family of enzymes

31 March 2020

1 reference

Characterization of the iron- and 2-oxoglutarate-binding sites of human prolyl 4-hydroxylase

31 March 2020

1 reference

Oxygenases: mechanisms and structural motifs for O(2) activation

31 March 2020

1 reference

Evolution of functional diversity in the cupin superfamily.

31 March 2020

1 reference

Structure of factor-inhibiting hypoxia-inducible factor 1: An asparaginyl hydroxylase involved in the hypoxic response pathway

31 March 2020

1 reference

Structure of factor-inhibiting hypoxia-inducible factor (HIF) reveals mechanism of oxidative modification of HIF-1 alpha

31 March 2020

1 reference

Structure of human FIH-1 reveals a unique active site pocket and interaction sites for HIF-1 and von Hippel-Lindau

31 March 2020

1 reference

Alteration of the co-substrate selectivity of deacetoxycephalosporin C synthase. The role of arginine 258

31 March 2020

1 reference

JmjC: cupin metalloenzyme-like domains in jumonji, hairless and phospholipase A2β

31 March 2020

1 reference

Substrate requirements of the oxygen-sensing asparaginyl hydroxylase factor-inhibiting hypoxia-inducible factor

31 March 2020

1 reference

Characterization of the human prolyl 4-hydroxylases that modify the hypoxia-inducible factor

31 March 2020

1 reference

Leu-574 of HIF-1alpha is essential for the von Hippel-Lindau (VHL)-mediated degradation pathway

31 March 2020

1 reference

Crystal structure of a clavaminate synthase-Fe(II)-2-oxoglutarate-substrate-NO complex: evidence for metal centered rearrangements

31 March 2020

1 reference

Crystallographic and Spectroscopic Characterization of a Nonheme Fe(IV)&cjs0811;O Complex

31 March 2020

1 reference

The first direct characterization of a high-valent iron intermediate in the reaction of an alpha-ketoglutarate-dependent dioxygenase: a high-spin FeIV complex in taurine/alpha-ketoglutarate dioxygenase (TauD) from Escherichia coli

31 March 2020

1 reference

Spectroscopic studies of substrate interactions with clavaminate synthase 2, a multifunctional alpha-KG-dependent non-heme iron enzyme: correlation with mechanisms and reactivities

31 March 2020

1 reference

O2- and alpha-ketoglutarate-dependent tyrosyl radical formation in TauD, an alpha-keto acid-dependent non-heme iron dioxygenase

31 March 2020

1 reference

Inactivation of 1-Aminocyclopropane-1-carboxylate Oxidase Involves Oxidative Modifications†

31 March 2020

1 reference

Prolyl 4-hydroxylases and their protein disulfide isomerase subunit

31 March 2020

1 reference

Structure and mechanism of anthocyanidin synthase from Arabidopsis thaliana

31 March 2020

1 reference

Hypoxia-inducible factor 1 levels vary exponentially over a physiologically relevant range of O2 tension

31 March 2020

1 reference

Catalytic properties of the asparaginyl hydroxylase (FIH) in the oxygen sensing pathway are distinct from those of its prolyl 4-hydroxylases

31 March 2020

1 reference

Regulation of the hypoxia-inducible factor 1alpha by the inflammatory mediators nitric oxide and tumor necrosis factor-alpha in contrast to desferroxamine and phenylarsine oxide

31 March 2020

1 reference

Nitric oxide impairs normoxic degradation of HIF-1alpha by inhibition of prolyl hydroxylases

31 March 2020

1 reference

Inhibition of hypoxia-inducible factor 1 activity by nitric oxide donors in hypoxia

31 March 2020

1 reference

Inhibition of hypoxia-inducible factor 1 activation by carbon monoxide and nitric oxide. Implications for oxygen sensing and signaling

31 March 2020

1 reference

HIF-1alpha-prolyl hydroxylase: molecular target of nitric oxide in the hypoxic signal transduction pathway

31 March 2020

1 reference

Redistribution of intracellular oxygen in hypoxia by nitric oxide: effect on HIF1alpha

31 March 2020

1 reference

Cobalt inhibits the interaction between hypoxia-inducible factor-alpha and von Hippel-Lindau protein by direct binding to hypoxia-inducible factor-alpha

31 March 2020

1 reference

Activation of the HIF pathway in cancer

31 March 2020

1 reference

Role of prolyl hydroxylation in oncogenically stabilized hypoxia-inducible factor-1alpha

31 March 2020

1 reference

AlkB-mediated oxidative demethylation reverses DNA damage in Escherichia coli

31 March 2020

1 reference

Oxidative demethylation by Escherichia coli AlkB directly reverts DNA base damage

31 March 2020

1 reference

Mutations in SDHD, a mitochondrial complex II gene, in hereditary paraganglioma

31 March 2020

1 reference

Hereditary paraganglioma targets diverse paraganglia

31 March 2020

1 reference

Germline mutations in FH predispose to dominantly inherited uterine fibroids, skin leiomyomata and papillary renal cell cancer

31 March 2020

1 reference

Mammalian EGLN genes have distinct patterns of mRNA expression and regulation

31 March 2020

1 reference

HIF-1-dependent transcriptional activity is required for oxygen-mediated HIF-1alpha degradation

31 March 2020

1 reference

The von Hippel Lindau/hypoxia-inducible factor (HIF) pathway regulates the transcription of the HIF-proline hydroxylase genes in response to low oxygen

31 March 2020

1 reference

SM-20 is a novel mitochondrial protein that causes caspase-dependent cell death in nerve growth factor-dependent neurons

31 March 2020

1 reference

Novel estrogen and tamoxifen induced genes identified by SAGE (Serial Analysis of Gene Expression)

31 March 2020

1 reference

The transcriptional activation function of the HIF-like factor requires phosphorylation at a conserved threonine

31 March 2020

1 reference

von Hippel-Lindau protein binds hyperphosphorylated large subunit of RNA polymerase II through a proline hydroxylation motif and targets it for ubiquitination

31 March 2020

1 reference

Oxygen and iron regulation of iron regulatory protein 2.

31 March 2020

1 reference

Role of iron (II)-2-oxoglutarate-dependent dioxygenases in the generation of hypoxia-induced phosphatidic acid through HIF-1/2 and von Hippel-Lindau-independent mechanisms.

31 March 2020

1 reference

Overexpression of human aspartyl(asparaginyl)beta-hydroxylase in hepatocellular carcinoma and cholangiocarcinoma

31 March 2020

1 reference

Biochemical purification and pharmacological inhibition of a mammalian prolyl hydroxylase acting on hypoxia-inducible factor

31 March 2020

1 reference

Analogues of dealanylalahopcin are inhibitors of human HIF prolyl hydroxylases

31 March 2020

1 reference

2-oxoglutarate analogue inhibitors of HIF prolyl hydroxylase

31 March 2020

1 reference

Activation of the hypoxia‐inducible factor pathway and stimulation of angiogenesis by application of prolyl hydroxylase inhibitors

31 March 2020

1 reference

Structural origins of the selectivity of the trifunctional oxygenase clavaminic acid synthase

31 March 2020

1 reference

Carbapenem biosynthesis: confirmation of stereochemical assignments and the role of CarC in the ring stereoinversion process from L-proline

31 March 2020

1 reference

Crystal structure of carbapenem synthase (CarC)

31 March 2020

1 reference

Carnitine biosynthesis in mammals

31 March 2020

1 reference

Human phytanoyl-CoA hydroxylase: resolution of the gene structure and the molecular basis of Refsum's disease

31 March 2020

1 reference

Human and bacterial oxidative demethylases repair alkylation damage in both RNA and DNA

31 March 2020

1 reference

The selectivity and inhibition of AlkB.

31 March 2020

1 reference

Identification of novel hypoxia dependent and independent target genes of the von Hippel-Lindau (VHL) tumour suppressor by mRNA differential expression profiling

31 March 2020

1 reference

Expression of hypoxia-inducible factor-1alpha and -2alpha in hypoxic and ischemic rat kidneys

31 March 2020

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=15122348

31 March 2020

Identifiers

2 references

30 April 2017

Consolidated OpenCitations Corpus – April 2017

Dimensions Publication ID

1034922949

0 references

1 reference

Consolidated OpenCitations Corpus – April 2017

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=15122348

PubMed publication ID

2 references

30 April 2017

Consolidated OpenCitations Corpus – April 2017