(Q29400446)

title

The role of Jun, Fos and the AP-1 complex in cell-proliferation and transformation (English)

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=1751545

14 April 2017

30 April 2017

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1751545

16 November 2022

transcription

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1751545

16 November 2022

1 reference

https://api.crossref.org/works/10.1016/0304-419X(91)90011-9

16 November 2022

1 reference

https://api.crossref.org/works/10.1016/0304-419X(91)90011-9

16 November 2022

Michael Karin

1 reference

14 April 2017

Peter Angel

1 reference

14 April 2017

P. Angel

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1751545

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=1751545

16 November 2022

language of work or name

1 reference

30 April 2017

publication date

December 1991

1 reference

14 April 2017

10 December 1991

1 reference

PubMed

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=1751545

full work available at URL

30 April 2017

https://api.elsevier.com/content/article/PII:0304419X91900119?httpAccept=text/xml

1 reference

https://api.crossref.org/works/10.1016/0304-419X(91)90011-9

https://api.elsevier.com/content/article/PII:0304419X91900119?httpAccept=text/plain

16 November 2022

1 reference

https://api.crossref.org/works/10.1016/0304-419X(91)90011-9

Biochimica et Biophysica Acta: Reviews on Cancer

16 November 2022

published in

1 reference

Biochimica et Biophysica Acta

14 April 2017

1 reference

PubMed

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=1751545

30 April 2017

volume

1072

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=1751545

14 April 2017

30 April 2017

issue

2-3

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=1751545

14 April 2017

30 April 2017

page(s)

129-157

1 reference

14 April 2017

129-57

1 reference

PubMed

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=1751545

The induction of differentiation in teratocarcinoma stem cells by retinoic acid

30 April 2017

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Metal-responsive elements act as positive modulators of human metallothionein-IIA enhancer activity

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In vivo competition between a metallothionein regulatory element and the SV40 enhancer

16 November 2022

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Phorbol ester-inducible genes contain a common cis element recognized by a TPA-modulated trans-acting factor

16 November 2022

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The role of protein kinase C in cell surface signal transduction and tumour promotion

16 November 2022

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Induction of metallothionein and other mRNA species by carcinogens and tumor promoters in primary human skin fibroblasts

16 November 2022

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Phorbol ester induces the transcriptional stimulatory activity of the SV40 enhancer

16 November 2022

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Metallothionein gene expression is regulated by serum factors and activators of protein kinase C

16 November 2022

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12-O-tetradecanoyl-phorbol-13-acetate induction of the human collagenase gene is mediated by an inducible enhancer element located in the 5'-flanking region

16 November 2022

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Prolonged activation of jun and collagenase genes by tumour necrosis factor-alpha

16 November 2022

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Isolation of the oncogene and epidermal growth factor-induced transin gene: complex control in rat fibroblasts

16 November 2022

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Purified transcription factor AP-1 interacts with TPA-inducible enhancer elements

16 November 2022

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Multiple cis- and trans-acting elements mediate the transcriptional response to phorbol esters

16 November 2022

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Transcription factor AP-2 mediates induction by two different signal-transduction pathways: protein kinase C and cAMP.

16 November 2022

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Characterization of DNA sequences through which cadmium and glucocorticoid hormones induce human metallothionein-IIA gene

16 November 2022

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Steroid receptor regulated transcription of specific genes and gene networks

16 November 2022

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Transient accumulation of c-fos RNA following serum stimulation requires a conserved 5' element and c-fos 3' sequences

16 November 2022

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In vitro activation of the HIV-1 enhancer in extracts from cells treated with a phorbol ester tumor promoter.

16 November 2022

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NF-kappa B: a pleiotropic mediator of inducible and tissue-specific gene control

16 November 2022

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Human proto-oncogene c-jun encodes a DNA binding protein with structural and functional properties of transcription factor AP-1

16 November 2022

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Oncogene jun encodes a sequence-specific trans-activator similar to AP-1.

16 November 2022

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The Fos complex and Fos-related antigens recognize sequence elements that contain AP-1 binding sites

16 November 2022

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Fos-associated protein p39 is the product of the jun proto-oncogene

16 November 2022

1 reference

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The c-Fos protein interacts with c-Jun/AP-1 to stimulate transcription of AP-1 responsive genes

16 November 2022

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fos-associated cellular p39 is related to nuclear transcription factor AP-1.

16 November 2022

1 reference

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GCN4 protein, synthesized in vitro, binds HIS3 regulatory sequences: implications for general control of amino acid biosynthetic genes in yeast

16 November 2022

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v-jun encodes a nuclear protein with enhancer binding properties of AP-1.

16 November 2022

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Induction of a factor that binds to the polyoma virus A enhancer on differentiation of embryonal carcinoma cells

16 November 2022

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Jun-B differs in its biological properties from, and is a negative regulator of, c-Jun

16 November 2022

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Nucleoprotein complexes that regulate gene expression in adipocyte differentiation: direct participation of c-fos

16 November 2022

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Identification of a 39,000-dalton protein in cells transformed by the FBJ murine osteosarcoma virus

16 November 2022

1 reference

https://api.crossref.org/works/10.1016/0304-419X(91)90011-9

Viral and cellular fos proteins are complexed with a 39,000-dalton cellular protein

16 November 2022

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https://api.crossref.org/works/10.1016/0304-419X(91)90011-9

The Fos protein complex is associated with DNA in isolated nuclei and binds to DNA cellulose

16 November 2022

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https://api.crossref.org/works/10.1016/0304-419X(91)90011-9

The role of the leucine zipper in the fos-jun interaction

16 November 2022

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DNA binding activities of three murine Jun proteins: stimulation by Fos.

16 November 2022

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c-Jun dimerizes with itself and with c-Fos, forming complexes of different DNA binding affinities

16 November 2022

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https://api.crossref.org/works/10.1016/0304-419X(91)90011-9

The product of a novel growth factor activated gene, fos B, interacts with JUN proteins enhancing their DNA binding activity

16 November 2022

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The product of a fos-related gene, fra-1, binds cooperatively to the AP-1 site with Jun: transcription factor AP-1 is comprised of multiple protein complexes.

16 November 2022

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Parallel association of Fos and Jun leucine zippers juxtaposes DNA binding domains

16 November 2022

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Leucine repeats and an adjacent DNA binding domain mediate the formation of functional cFos-cJun heterodimers

16 November 2022

1 reference

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Fos-Jun interaction: mutational analysis of the leucine zipper domain of both proteins

16 November 2022

1 reference

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Different requirements for formation of Jun: Jun and Jun: Fos complexes

16 November 2022

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The leucine zipper: a hypothetical structure common to a new class of DNA binding proteins

16 November 2022

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Evidence that the leucine zipper is a coiled coil

16 November 2022

1 reference

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Preferential heterodimer formation by isolated leucine zippers from fos and jun

16 November 2022

1 reference

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A cluster of phosphorylation sites on the cyclic AMP-regulated nuclear factor CREB predicted by its sequence

16 November 2022

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Leucine zippers of fos, jun and GCN4 dictate dimerization specificity and thereby control DNA binding

16 November 2022

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Changing fos oncoprotein to a jun-independent DNA binding protein with GCN4 dimerization specificity by swapping "leucine zippers".

16 November 2022

1 reference

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A Fos protein containing the Jun leucine zipper forms a homodimer which binds to the AP1 binding site.

16 November 2022

1 reference

https://api.crossref.org/works/10.1016/0304-419X(91)90011-9

Fos and Jun bind cooperatively to the AP-1 site: reconstitution in vitro

16 November 2022

1 reference

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Transcription factor ATF cDNA clones: an extensive family of leucine zipper proteins able to selectively form DNA-binding heterodimers

16 November 2022

1 reference

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Two functionally different regions in Fos are required for the sequence-specific DNA interaction of the Fos/Jun protein complex

16 November 2022

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How eukaryotic transcriptional activators work

16 November 2022

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Biochemical analysis of transcriptional activation by Jun: differential activity of c- and v-Jun

16 November 2022

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Dissection of functional domains of the pituitary-specific transcription factor GHF-1.

16 November 2022

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The pituitary-specific transcription factor GHF-1 is a homeobox-containing protein

16 November 2022

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Fos and jun cooperate in transcriptional regulation via heterologous activation domains

16 November 2022

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Direct interaction between fos and jun nuclear oncoproteins: role of the 'leucine zipper' domain.

16 November 2022

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Stimulation of 3T3 cells induces transcription of the c-fos proto-oncogene

16 November 2022

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Platelet-derived growth factor induces rapid but transient expression of the c-fos gene and protein

16 November 2022

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Induction of c-fos gene and protein by growth factors precedes activation of c-myc

16 November 2022

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The jun proto-oncogene is positively autoregulated by its product, Jun/AP-1

16 November 2022

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Transcriptional activation of c-jun during the G0/G1 transition in mouse fibroblasts

16 November 2022

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Induction of proto-oncogene JUN/AP-1 by serum and TPA.

16 November 2022

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Posttranscriptional regulation of c-fos mRNA expression

16 November 2022

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Autoinduction of transforming growth factor beta 1 is mediated by the AP-1 complex

16 November 2022

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Enhanced jun gene expression is an early genomic response to transforming growth factor beta stimulation

16 November 2022

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Disappearance of Ca2+-sensitive, phospholipid-dependent protein kinase activity in phorbol ester-treated 3T3 cells

16 November 2022

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Transcriptional autoregulation of the proto-oncogene fos.

16 November 2022

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Proto-oncogene fos: complex but versatile regulation

16 November 2022

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'Nuclear' oncogenes convert extracellular stimuli into changes in the genetic program

16 November 2022

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Superinduction of c-fos by nerve growth factor in the presence of peripherally active benzodiazepines.

16 November 2022

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Induction of the c-fos oncogene by thyrotropic hormone in rat thyroid cells in culture

16 November 2022

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Inhibition of proto-oncogene c-fos transcription by inhibitors of protein kinase C and ion transport

16 November 2022

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c-fos sequence necessary for basal expression and induction by epidermal growth factor, 12-O-tetradecanoyl phorbol-13-acetate and the calcium ionophore

16 November 2022

105

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Role of ion flux in the control of c-fos expression

16 November 2022

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Growth factors and membrane depolarization activate distinct programs of early response gene expression: dissociation of fos and jun induction

16 November 2022

108

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Stimulation of neuronal acetylcholine receptors induces rapid gene transcription

16 November 2022

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The heat shock response in HeLa cells is accompanied by elevated expression of the c-fos proto-oncogene

16 November 2022

110

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Involvement of common and cell type-specific pathways in c-fos gene control: stable induction of cAMP in macrophages

16 November 2022

111

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Mutation of the c-fos gene dyad symmetry element inhibits serum inducibility of transcription in vivo and the nuclear regulatory factor binding in vitro

16 November 2022

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The catalytic subunit of cAMP-dependent protein kinase induces expression of genes containing cAMP-responsive enhancer elements

16 November 2022

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Multiple protein-binding sites in the 5'-flanking region regulate c-fos expression

16 November 2022

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Inducible binding of a factor to the c-fos enhancer

16 November 2022

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The c-fos serum response element responds to protein kinase C-dependent and -independent signals but not to cyclic AMP.

16 November 2022

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Isolation and properties of cDNA clones encoding SRF, a transcription factor that binds to the c-fos serum response element

16 November 2022

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The ability of a ternary complex to form over the serum response element correlates with serum inducibility of the human c-fos promoter

16 November 2022

120

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Occupation of the c-fos serum response element in vivo by a multi-protein complex is unaltered by growth factor induction

16 November 2022

122

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Casein kinase II enhances the DNA binding activity of serum response factor

16 November 2022

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Activation of protein kinase C decreases phosphorylation of c-Jun at sites that negatively regulate its DNA-binding activity

16 November 2022

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A family of immunologically related transcription factors that includes multiple forms of ATF and AP-1

16 November 2022

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Multisite phosphorylation of glycogen synthase

16 November 2022

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Modification of fos proteins: phosphorylation of c-fos, but not v-fos, is stimulated by 12-tetradecanoyl-phorbol-13-acetate and serum

16 November 2022

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Antitumor promotion and antiinflammation: down-modulation of AP-1 (Fos/Jun) activity by glucocorticoid hormone

16 November 2022

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Transcriptional interference between c-Jun and the glucocorticoid receptor: mutual inhibition of DNA binding due to direct protein-protein interaction.

16 November 2022

134

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Functional antagonism between oncoprotein c-Jun and the glucocorticoid receptor

16 November 2022

135

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Mutual transrepression of Fos and the glucocorticoid receptor: involvement of a functional domain in Fos which is absent in FosB

16 November 2022

136

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General repression of enhanson activity by the adenovirus-2 E1A proteins

16 November 2022

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A novel function of the transforming domain of E1a: repression of AP-1 activity

16 November 2022

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Mechanisms of Glucocorticoid Action on Immune Processes

16 November 2022

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Half-life of synovial cell collagenase mRNA is modulated by phorbol myristate acetate but not by all-trans-retinoic acid or dexamethasone

16 November 2022

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Co-localization of elements required for phorbol ester stimulation and glucocorticoid repression of proliferin gene expression

16 November 2022

142

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The steroid and thyroid hormone receptor superfamily

16 November 2022

143

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16 November 2022

144

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Trans-acting protein factors and the regulation of eukaryotic transcription: lessons from studies on DNA tumor viruses

16 November 2022

145

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16 November 2022

146

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Negative effect of the transcriptional activator GAL4

16 November 2022

147

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jun-B inhibits and c-fos stimulates the transforming and trans-activating activities of c-jun

16 November 2022

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SCIP: a glial POU domain gene regulated by cyclic AMP.

16 November 2022

151

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A naturally occurring truncated form of FosB that inhibits Fos/Jun transcriptional activity

16 November 2022

152

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Cyclic AMP-responsive DNA-binding protein: structure based on a cloned placental cDNA

16 November 2022

153

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Transient induction of c-jun during hepatic regeneration

16 November 2022

155

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c-fos expression is neither sufficient nor obligatory for differentiation of monomyelocytes to macrophages.

16 November 2022

156

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A conserved AU sequence from the 3' untranslated region of GM-CSF mRNA mediates selective mRNA degradation

16 November 2022

157

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The c-fos transcript is targeted for rapid decay by two distinct mRNA degradation pathways

16 November 2022

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16 November 2022

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Requirement for fos gene expression in the transcriptional activation of collagenase by other oncogenes and phorbol esters

16 November 2022

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Fos C-terminal mutations block down-regulation of c-fos transcription following serum stimulation.

16 November 2022

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Viral and cellular fos proteins: A comparative analysis

16 November 2022

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The leucine repeat motif in Fos protein mediates complex formation with Jun/AP-1 and is required for transformation

16 November 2022

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Transcriptional activation and repression by Fos are independent functions: the C terminus represses immediate-early gene expression via CArG elements

16 November 2022

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Autoregulation of fos: the dyad symmetry element as the major target of repression.

16 November 2022

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16 November 2022

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Mouse teratocarcinoma cells: prospects for the study of embryogenesis and neoplasia

16 November 2022

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16 November 2022

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Differentiation-responsive elements in the 5' region of the mouse tissue plasminogen activator gene confer two-stage regulation by retinoic acid and cyclic AMP in teratocarcinoma cells

16 November 2022

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Activation of an intron enhancer within the keratin 18 gene by expression of c-fos and c-jun in undifferentiated F9 embryonal carcinoma cells

16 November 2022

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Identification of a retinoic acid responsive element in the retinoic acid receptor beta gene

16 November 2022

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Jun-Fos and receptors for vitamins A and D recognize a common response element in the human osteocalcin gene

16 November 2022

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16 November 2022

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A macrophage factor inhibits adipocyte gene expression: an in vitro model of cachexia

16 November 2022

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Multiple hormone interactions in the developmental biology of the mammary gland

16 November 2022

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Epidermal growth factor stimulates transcription of the c-jun proto-oncogene in rat fibroblasts

16 November 2022

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Microinjection of fos-specific antibodies blocks DNA synthesis in fibroblast cells.

16 November 2022

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Expression of raf oncogenes activates the PEA1 transcription factor motif

16 November 2022

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Interleukin-1 costimulatory activity on the interleukin-2 promoter via AP-1

16 November 2022

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16 November 2022

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16 November 2022

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16 November 2022

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Early signals in the mitogenic response

16 November 2022

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16 November 2022

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16 November 2022

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Efficient transformation of chicken embryo fibroblasts by c-Jun requires structural modification in coding and noncoding sequences

16 November 2022

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The JUN oncoprotein, a vertebrate transcription factor, activates transcription in yeast.

16 November 2022

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16 November 2022

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16 November 2022

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Virus Induction of Osteosarcomas in Mice

16 November 2022

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c-fos protein can induce cellular transformation: a novel mechanism of activation of a cellular oncogene.

16 November 2022

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16 November 2022

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16 November 2022

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Activation of the neu tyrosine kinase induces the fos/jun transcription factor complex, the glucose transporter and ornithine decarboxylase

16 November 2022

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16 November 2022

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Requirement for c-ras proteins during viral oncogene transformation

16 November 2022

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16 November 2022

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The c-Ha-ras oncogene and a tumor promoter activate the polyoma virus enhancer

16 November 2022

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The origin of human cancers

16 November 2022

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16 November 2022

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16 November 2022

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16 November 2022

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16 November 2022

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UV-induced DNA damage is an intermediate step in UV-induced expression of human immunodeficiency virus type 1, collagenase, c-fos, and metallothionein

16 November 2022

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Activation of human immunodeficiency virus type 1 by DNA damage in human cells

16 November 2022

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UV-induced extracellular factor from human fibroblasts communicates the UV response to nonirradiated cells

16 November 2022

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16 November 2022

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16 November 2022

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16 November 2022

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16 November 2022

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The function and mechanism of promoters of carcinogenesis

16 November 2022

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16 November 2022

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16 November 2022

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16 November 2022

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Three stage carcinogenesis in mouse skin--recent results and present status of an advanced model system of chemical carcinogenesis

16 November 2022

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Tumor promoter 12-O-tetradecanoyl-phorbol-13-acetate enhances sister chromatid exchanges and numerical and structural chromosome aberrations in primary mouse epidermal cell cultures

16 November 2022

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Suppression of tumor promoter phorbolmyristate acetate-induced chromosome breakage by antioxidants and inhibitors of arachidonic acid metabolism

16 November 2022

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16 November 2022

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Regulation of gene expression by tumor promoters

16 November 2022

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16 November 2022

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16 November 2022

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Tumour promoter induces anchorage independence irreversibly

16 November 2022

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Transfer of sensitivity to tumor promoters by transfection of DNA from sensitive into insensitive mouse JB6 epidermal cells

16 November 2022

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AP1/jun function is differentially induced in promotion-sensitive and resistant JB6 cells.

16 November 2022

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16 November 2022

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16 November 2022

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Metalloproteinases and their inhibitors in matrix remodeling

16 November 2022

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16 November 2022

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16 November 2022

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Transforming growth factor-alpha stimulates proto-oncogene c-jun expression and a mitogenic program in primary cultures of adult rat hepatocytes

16 November 2022

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Cachectin/TNF and IL-1 induced by glucose-modified proteins: role in normal tissue remodeling

16 November 2022

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Transforming growth factor alpha

16 November 2022

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Interleukin 1 regulates human metallothionein gene expression

16 November 2022

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Participation of monocyte-macrophages and lymphocytes in the production of a factor that stimulates collagenase and prostaglandin release by rheumatoid synovial cells

16 November 2022

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16 November 2022

Identifiers

2 references

14 April 2017

Consolidated OpenCitations Corpus – April 2017

133264

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=1751545