(Q28593591)

31 January 2017

title

DOCK2 is essential for antigen-induced translocation of TCR and lipid rafts, but not PKC-theta and LFA-1, in T cells (English)

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Dedicator of cyto-kinesis 2

31 January 2017

main subject

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GOA release 2020-03-11

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Yoshinori Fukui

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Terukazu Sanui

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31 January 2017

Ayumi Inayoshi

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31 January 2017

Mayuko Noda

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31 January 2017

Eiko Iwata

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31 January 2017

Masahiro Oike

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31 January 2017

Takehiko Sasazuki

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31 January 2017

language of work or name

English

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publication date

1 July 2003

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31 January 2017

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31 January 2017

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31 January 2017

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31 January 2017

page(s)

119–129

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Distinct patterns of membrane microdomain partitioning in Th1 and th2 cells.

31 January 2017

cites work

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7 January 2021

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Antigen/MHC-specific T cells are preferentially exported from the thymus in the presence of their MHC ligand.

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7 January 2021

Antigen-induced translocation of PKC-theta to membrane rafts is required for T cell activation

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7 January 2021

Unconventional Rac-GEF activity is mediated through the Dock180-ELMO complex

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7 January 2021

Cutting edge: quantitative imaging of raft accumulation in the immunological synapse

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7 January 2021

The Rho-family GTP exchange factor Vav is a critical transducer of T cell receptor signals to the calcium, ERK, and NF-kappaB pathways

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7 January 2021

Phosphotyrosine-dependent activation of Rac-1 GDP/GTP exchange by the vav proto-oncogene product

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7 January 2021

The immunological synapse and the actin cytoskeleton: molecular hardware for T cell signaling.

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7 January 2021

Drosophila myoblast city encodes a conserved protein that is essential for myoblast fusion, dorsal closure, and cytoskeletal organization

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7 January 2021

Vav is a regulator of cytoskeletal reorganization mediated by the T-cell receptor

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7 January 2021

Defective T-cell receptor signalling and positive selection of Vav-deficient CD4+ CD8+ thymocytes

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7 January 2021

Haematopoietic cell-specific CDM family protein DOCK2 is essential for lymphocyte migration

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7 January 2021

The T-cell receptor regulates Akt (protein kinase B) via a pathway involving Rac1 and phosphatidylinositide 3-kinase

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7 January 2021

The GTPase Rac-1 controls cell fate in the thymus by diverting thymocytes from positive to negative selection.

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7 January 2021

The immunological synapse: a molecular machine controlling T cell activation

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7 January 2021

Positive Regulation of T Cell Activation and Integrin Adhesion by the Adapter Fyb/Slap

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7 January 2021

Rac function and regulation during Drosophila development.

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7 January 2021

Rho GTPases and the actin cytoskeleton

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7 January 2021

Defects in actin-cap formation in Vav-deficient mice implicate an actin requirement for lymphocyte signal transduction

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7 January 2021

CD28 plays a critical role in the segregation of PKC theta within the immunologic synapse

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7 January 2021

Activation of Rac1 by a Crk SH3-binding protein, DOCK180

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7 January 2021

Vav regulates peptide-specific apoptosis in thymocytes

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7 January 2021

Human CD8+ T cells do not require the polarization of lipid rafts for activation and proliferation

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7 January 2021

Cbl-b is a negative regulator of receptor clustering and raft aggregation in T cells

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7 January 2021

Vav1 controls integrin clustering and MHC/peptide-specific cell adhesion to antigen-presenting cells

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7 January 2021

Differential clustering of CD4 and CD3zeta during T cell recognition

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7 January 2021

T cell receptor signaling precedes immunological synapse formation

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7 January 2021

Integrin-mediated long-term B cell retention in the splenic marginal zone.

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Kinetics of T-cell receptor binding to peptide/I-Ek complexes: correlation of the dissociation rate with T-cell responsiveness

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7 January 2021

Selective modulation of protein kinase C-theta during T-cell activation

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7 January 2021

Three-dimensional segregation of supramolecular activation clusters in T cells

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7 January 2021

The common cytokine receptor gamma chain plays an essential role in regulating lymphoid homeostasis

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7 January 2021

DOCK2 mediates T cell receptor-induced activation of Rac2 and IL-2 transcription

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7 January 2021

Myoblast city, the Drosophila homolog of DOCK180/CED-5, is required in a Rac signaling pathway utilized for multiple developmental processes

1 reference

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7 January 2021

The Actin Cytoskeleton and Lymphocyte Activation

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7 January 2021

Coupling of the TCR to integrin activation by Slap-130/Fyb.

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7 January 2021

Tyrosine phosphorylation of Pyk2 is selectively regulated by Fyn during TCR signaling

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7 January 2021

CED-2/CrkII and CED-10/Rac control phagocytosis and cell migration in Caenorhabditis elegans

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7 January 2021

Vav1 transduces T cell receptor signals to the activation of phospholipase C-gamma1 via phosphoinositide 3-kinase-dependent and -independent pathways.

1 reference

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7 January 2021

PKC-θ is required for TCR-induced NF-κB activation in mature but not immature T lymphocytes

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7 January 2021

Defective antigen receptor-mediated proliferation of B and T cells in the absence of Vav.

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7 January 2021

A Requirement for the Rho-Family GTP Exchange Factor Vav in Positive and Negative Selection of Thymocytes

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7 January 2021

A novel functional interaction between Vav and PKCtheta is required for TCR-induced T cell activation.

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7 January 2021

Vav1/Rac-dependent actin cytoskeleton reorganization is required for lipid raft clustering in T cells

1 reference

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7 January 2021

Translocation of PKC[theta] in T cells is mediated by a nonconventional, PI3-K- and Vav-dependent pathway, but does not absolutely require phospholipase C

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2803%2900169-9

7 January 2021

T lymphocyte costimulation mediated by reorganization of membrane microdomains

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7 January 2021

Regulated nuclear import of Rel proteins in the Drosophila immune response

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7 January 2021

Vav and SLP-76 interact and functionally cooperate in IL-2 gene activation

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2803%2900169-9

7 January 2021

The vav exchange factor is an essential regulator in actin-dependent receptor translocation to the lymphocyte-antigen-presenting cell interface

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2803%2900169-9

7 January 2021

A receptor/cytoskeletal movement triggered by costimulation during T cell activation

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2803%2900169-9

7 January 2021

Visualizing the dynamics of T cell activation: intracellular adhesion molecule 1 migrates rapidly to the T cell/B cell interface and acts to sustain calcium levels

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2803%2900169-9

7 January 2021

Non-CD28 costimulatory molecules present in T cell rafts induce T cell costimulation by enhancing the association of TCR with rafts.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2803%2900169-9

7 January 2021

Deficiency of small GTPase Rac2 affects T cell activation

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2803%2900169-9

7 January 2021

Defective signalling through the T- and B-cell antigen receptors in lymphoid cells lacking the vav proto-oncogene

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2803%2900169-9

7 January 2021

10.1016/S1074-7613(03)00169-9

Identifiers

DOI

1 reference

Consolidated OpenCitations Corpus – April 2017

1 reference

Consolidated OpenCitations Corpus – April 2017

1 reference

Consolidated OpenCitations Corpus – April 2017