(Q28590612)

English

Inactivation of bcl-2 results in progressive degeneration of motoneurons, sympathetic and sensory neurons during early postnatal development

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PubMed publication ID

31 January 2017

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8755480%20AND%20SRC:MED&resulttype=core&format=json

18 October 2019

Inactivation of bcl-2 results in progressive degeneration of motoneurons, sympathetic and sensory neurons during early postnatal development (English)

2 references

PubMed publication ID

31 January 2017

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8755480%20AND%20SRC:MED&resulttype=core&format=json

18 October 2019

B cell leukemia/lymphoma 2

1 reference

GOA release 2020-03-11

Michael Sendtner

2

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8755480%20AND%20SRC:MED&resulttype=core&format=json

18 October 2019

Jonathan D. Cooper

3

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8755480%20AND%20SRC:MED&resulttype=core&format=json

18 October 2019

author name string

T M Michaelidis

1

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8755480%20AND%20SRC:MED&resulttype=core&format=json

18 October 2019

M S Airaksinen

4

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8755480%20AND%20SRC:MED&resulttype=core&format=json

18 October 2019

B Holtmann

5

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8755480%20AND%20SRC:MED&resulttype=core&format=json

18 October 2019

M Meyer

6

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8755480%20AND%20SRC:MED&resulttype=core&format=json

18 October 2019

H Thoenen

7

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8755480%20AND%20SRC:MED&resulttype=core&format=json

18 October 2019

language of work or name

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publication date

1 July 1996

2 references

PubMed publication ID

31 January 2017

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8755480%20AND%20SRC:MED&resulttype=core&format=json

18 October 2019

language of work

2 references

PubMed publication ID

31 January 2017

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8755480%20AND%20SRC:MED&resulttype=core&format=json

18 October 2019

17

2 references

PubMed publication ID

31 January 2017

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8755480%20AND%20SRC:MED&resulttype=core&format=json

18 October 2019

1

2 references

PubMed publication ID

31 January 2017

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8755480%20AND%20SRC:MED&resulttype=core&format=json

18 October 2019

75-89

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8755480%20AND%20SRC:MED&resulttype=core&format=json

18 October 2019

Bcl-2 gene is highly expressed during neurogenesis in the central nervous system

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2800%2980282-2

7 January 2021

based on heuristic

inferred from DOI database lookup

The proto-oncogene bcl-2 can selectively rescue neurotrophic factor-dependent neurons from apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2800%2980282-2

7 January 2021

based on heuristic

inferred from DOI database lookup

Role of Bcl-2 in the brain-derived neurotrophic factor survival response

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2800%2980282-2

7 January 2021

based on heuristic

inferred from DOI database lookup

Cloning the chromosomal breakpoint of t(14;18) human lymphomas: clustering around JH on chromosome 14 and near a transcriptional unit on 18.

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2800%2980282-2

7 January 2021

based on heuristic

inferred from DOI database lookup

Trophic factors and neuronal survival

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2800%2980282-2

7 January 2021

based on heuristic

inferred from DOI database lookup

bcl-x, a bcl-2-related gene that functions as a dominant regulator of apoptotic cell death

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2800%2980282-2

7 January 2021

based on heuristic

inferred from DOI database lookup

Involvement of ras p21 in neurotrophin-induced response of sensory, but not sympathetic neurons

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2800%2980282-2

7 January 2021

based on heuristic

inferred from DOI database lookup

Functional Interactions of Neurotrophins and Neurotrophin Receptors

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2800%2980282-2

7 January 2021

based on heuristic

inferred from DOI database lookup

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2800%2980282-2

7 January 2021

based on heuristic

inferred from DOI database lookup

Neurotrophin receptors: a window into neuronal differentiation

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2800%2980282-2

7 January 2021

based on heuristic

inferred from DOI database lookup

Grasping objects: the cortical mechanisms of visuomotor transformation

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2800%2980282-2

7 January 2021

based on heuristic

inferred from DOI database lookup

Cloning and structural analysis of cDNAs for bcl-2 and a hybrid bcl-2/immunoglobulin transcript resulting from the t(14;18) translocation

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2800%2980282-2

7 January 2021

based on heuristic

inferred from DOI database lookup

The dependence of motoneurons on their target muscle during postnatal development of the mouse.

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2800%2980282-2

7 January 2021

based on heuristic

inferred from DOI database lookup

Dorsal root ganglion cell death and surviving cell numbers in relation to the development of sensory innervation in the rat hindlimb

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2800%2980282-2

7 January 2021

based on heuristic

inferred from DOI database lookup

Neuronal deficits, not involving motor neurons, in mice lacking BDNF and/or NT4

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2800%2980282-2

7 January 2021

based on heuristic

inferred from DOI database lookup

Mice lacking nerve growth factor display perinatal loss of sensory and sympathetic neurons yet develop basal forebrain cholinergic neurons

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2800%2980282-2

7 January 2021

based on heuristic

inferred from DOI database lookup

The role of neurotrophins in the developing nervous system

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2800%2980282-2

7 January 2021

based on heuristic

inferred from DOI database lookup

Time course of axotomy-induced apoptotic cell death in facial motoneurons of neonatal wild type and bcl-2 transgenic mice

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2800%2980282-2

7 January 2021

based on heuristic

inferred from DOI database lookup

Neonatal motoneurons overexpressing the bcl-2 protooncogene in transgenic mice are protected from axotomy-induced cell death.

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2800%2980282-2

7 January 2021

based on heuristic

inferred from DOI database lookup

Mechanisms and Functions of Cell Death

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2800%2980282-2

7 January 2021

based on heuristic

inferred from DOI database lookup

Lack of neurotrophin-3 leads to deficiencies in the peripheral nervous system and loss of limb proprioceptive afferents

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2800%2980282-2

7 January 2021

based on heuristic

inferred from DOI database lookup

Severe sensory and sympathetic deficits in mice lacking neurotrophin-3.

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2800%2980282-2

7 January 2021

based on heuristic

inferred from DOI database lookup

bcl-2 transgene expression can protect neurons against developmental and induced cell death

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2800%2980282-2

7 January 2021

based on heuristic

inferred from DOI database lookup

Function and expression of the Bcl-x gene in the developing and adult nervous system.

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2800%2980282-2

7 January 2021

based on heuristic

inferred from DOI database lookup

Prevention of programmed cell death of sympathetic neurons by the bcl-2 proto-oncogene

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2800%2980282-2

7 January 2021

based on heuristic

inferred from DOI database lookup

Up-regulation of bax and down-regulation of bc1–2 is associated with kainate-induced apoptosis in mouse brain

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2800%2980282-2

7 January 2021

based on heuristic

inferred from DOI database lookup

bcl-x is expressed in embryonic and postnatal neural tissues and functions to prevent neuronal cell death

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2800%2980282-2

7 January 2021

based on heuristic

inferred from DOI database lookup

Role of BCL-2 in the survival and function of developing and mature sympathetic neurons

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2800%2980282-2

7 January 2021

based on heuristic

inferred from DOI database lookup

Immunohistochemical detection of Bax and Bcl-2 proteins in gerbil hippocampus following transient forebrain ischemia

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2800%2980282-2

7 January 2021

based on heuristic

inferred from DOI database lookup

Neurotrophic factor therapy for nervous system degenerative diseases

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2800%2980282-2

7 January 2021

based on heuristic

inferred from DOI database lookup

Neurotrophins promote motor neuron survival and are present in embryonic limb bud.

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2800%2980282-2

7 January 2021

based on heuristic

inferred from DOI database lookup

Bcl-2 is an inner mitochondrial membrane protein that blocks programmed cell death

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2800%2980282-2

7 January 2021

based on heuristic

inferred from DOI database lookup

BCL2 protein is topographically restricted in tissues characterized by apoptotic cell death

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2800%2980282-2

7 January 2021

based on heuristic

inferred from DOI database lookup

Members of several gene families influence survival of rat motoneurons in vitro and in vivo.

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2800%2980282-2

7 January 2021

based on heuristic

inferred from DOI database lookup

Molecular mechanisms of developmental neuronal death

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2800%2980282-2

7 January 2021

based on heuristic

inferred from DOI database lookup

Targeted disruption of the BDNF gene perturbs brain and sensory neuron development but not motor neuron development.

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2800%2980282-2

7 January 2021

based on heuristic

inferred from DOI database lookup

Evidence that brain-derived neurotrophic factor is a trophic factor for motor neurons in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2800%2980282-2

7 January 2021

based on heuristic

inferred from DOI database lookup

Neurotrophin 4/5 is a trophic factor for mammalian facial motor neurons

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2800%2980282-2

7 January 2021

based on heuristic

inferred from DOI database lookup

Differential regulation of motor neuron survival and choline acetyltransferase expression following axotomy

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2800%2980282-2

7 January 2021

based on heuristic

inferred from DOI database lookup

MCL1, a gene expressed in programmed myeloid cell differentiation, has sequence similarity to BCL2

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2800%2980282-2

7 January 2021

based on heuristic

inferred from DOI database lookup

Upregulation of bax protein levels in neurons following cerebral ischemia.

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2800%2980282-2

7 January 2021

based on heuristic

inferred from DOI database lookup

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2800%2980282-2

7 January 2021

based on heuristic

inferred from DOI database lookup

Homeosis in the mouse induced by a null mutation in the Hox-3.1 gene

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2800%2980282-2

7 January 2021

based on heuristic

inferred from DOI database lookup

The nerve growth factor 35 years later

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2800%2980282-2

7 January 2021

based on heuristic

inferred from DOI database lookup

Physiology of the neurotrophins

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2800%2980282-2

7 January 2021

based on heuristic

inferred from DOI database lookup

Neurotrophic agents prevent motoneuron death following sciatic nerve section in the neonatal mouse

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2800%2980282-2

7 January 2021

based on heuristic

inferred from DOI database lookup

Neurotrophic factors: from molecule to man.

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2800%2980282-2

7 January 2021

based on heuristic

inferred from DOI database lookup

Sensory but not motor neuron deficits in mice lacking NT4 and BDNF

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2800%2980282-2

7 January 2021

based on heuristic

inferred from DOI database lookup

The protooncogene bcl-2 inhibits apoptosis in PC12 cells

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2800%2980282-2

7 January 2021

based on heuristic

inferred from DOI database lookup

Overexpression of BCL-2 in transgenic mice protects neurons from naturally occurring cell death and experimental ischemia

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2800%2980282-2

7 January 2021

based on heuristic

inferred from DOI database lookup

The nerve growth factor family of receptors

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2800%2980282-2

7 January 2021

based on heuristic

inferred from DOI database lookup

Massive cell death of immature hematopoietic cells and neurons in Bcl-x-deficient mice

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2800%2980282-2

7 January 2021

based on heuristic

inferred from DOI database lookup

Targeted disruption of Bcl-2 alpha beta in mice: occurrence of gray hair, polycystic kidney disease, and lymphocytopenia

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2800%2980282-2

7 January 2021

based on heuristic

inferred from DOI database lookup

Molecular analysis of mbcl-2: structure and expression of the murine gene homologous to the human gene involved in follicular lymphoma

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2800%2980282-2

7 January 2021

based on heuristic

inferred from DOI database lookup

Neutralizing anti-p21ras Fabs suppress rat sympathetic neuron survival induced by NGF, LIF, CNTF and cAMP

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2800%2980282-2

7 January 2021

based on heuristic

inferred from DOI database lookup

Active p21Ras is sufficient for rescue of NGF-dependent rat sympathetic neurons

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2800%2980282-2

7 January 2021

based on heuristic

inferred from DOI database lookup

Cell density increases Bcl-2 and Bcl-x expression in addition to survival of cultured cerebellar granule neurons

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2800%2980282-2

7 January 2021

based on heuristic

inferred from DOI database lookup

Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programmed cell death

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2800%2980282-2

7 January 2021

based on heuristic

inferred from DOI database lookup

Reduction of naturally occurring motoneuron death in vivo by a target-derived neurotrophic factor

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2800%2980282-2

7 January 2021

based on heuristic

inferred from DOI database lookup

Cell death during development of the nervous system

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2800%2980282-2

7 January 2021

based on heuristic

inferred from DOI database lookup

Brain-derived neurotrophic factor rescues developing avian motoneurons from cell death

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2800%2980282-2

7 January 2021

based on heuristic

inferred from DOI database lookup

Social controls on cell survival and cell death

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2800%2980282-2

7 January 2021

based on heuristic

inferred from DOI database lookup

Inactivation of MyoD in mice leads to up-regulation of the myogenic HLH gene Myf-5 and results in apparently normal muscle development.

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2800%2980282-2

7 January 2021

based on heuristic

inferred from DOI database lookup

Motoneuron death after sciatic nerve section in newborn rats

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2800%2980282-2

7 January 2021

based on heuristic

inferred from DOI database lookup

Ciliary neurotrophic factor prevents the degeneration of motor neurons after axotomy.

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2800%2980282-2

7 January 2021

based on heuristic

inferred from DOI database lookup

Brain-derived neurotrophic factor prevents the death of motoneurons in newborn rats after nerve section

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2800%2980282-2

7 January 2021

based on heuristic

inferred from DOI database lookup

Inhibition of thymocyte apoptosis and negative antigenic selection in bcl-2 transgenic mice

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2800%2980282-2

7 January 2021

based on heuristic

inferred from DOI database lookup

Non-TrkA-expressing small DRG neurons are lost in TrkA deficient mice

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2800%2980282-2

7 January 2021

based on heuristic

inferred from DOI database lookup

Axotomy-induced neuronal death during development

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2800%2980282-2

7 January 2021

based on heuristic

inferred from DOI database lookup

Functions of the neurotrophins during nervous system development: what the knockouts are teaching us.

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2800%2980282-2

7 January 2021

based on heuristic

inferred from DOI database lookup

Detection of specific sequences among DNA fragments separated by gel electrophoresis

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2800%2980282-2

7 January 2021

based on heuristic

inferred from DOI database lookup

Trophic support of motoneurons: physiological, pathophysiological, and therapeutic implications.

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2800%2980282-2

7 January 2021

based on heuristic

inferred from DOI database lookup

Cloning of the chromosome breakpoint of neoplastic B cells with the t(14;18) chromosome translocation

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2800%2980282-2

7 January 2021

based on heuristic

inferred from DOI database lookup

Introduction of the negative selection marker into replacement vectors by a single ligation step

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2800%2980282-2

7 January 2021

based on heuristic

inferred from DOI database lookup

Bcl-2-deficient mice demonstrate fulminant lymphoid apoptosis, polycystic kidneys, and hypopigmented hair

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2800%2980282-2

7 January 2021

based on heuristic

inferred from DOI database lookup

Developmental neuron death in the rat superior cervical sympathetic ganglion: cell counts and ultrastructure.

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2800%2980282-2

7 January 2021

based on heuristic

inferred from DOI database lookup

Brain-derived neurotrophic factor rescues spinal motor neurons from axotomy-induced cell death

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2800%2980282-2

7 January 2021

based on heuristic

inferred from DOI database lookup

Bad, a heterodimeric partner for Bcl-XL and Bcl-2, displaces Bax and promotes cell death

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2800%2980282-2

7 January 2021

based on heuristic

inferred from DOI database lookup

A negative regulatory element in the bcl-2 5'-untranslated region inhibits expression from an upstream promoter

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2800%2980282-2

7 January 2021

based on heuristic

inferred from DOI database lookup

Identifiers

10.1016/S0896-6273(00)80282-2

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8755480%20AND%20SRC:MED&resulttype=core&format=json

18 October 2019

release_isq4uufowjhmzbjlmdvpeeoqpm

1 reference

https://api.fatcat.wiki/v0/release/isq4uufowjhmzbjlmdvpeeoqpm

24 November 2022

based on heuristic

mapped directly with Wikidata item

PubMed publication ID

2 references

PubMed publication ID

31 January 2017

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8755480%20AND%20SRC:MED&resulttype=core&format=json

18 October 2019

ResearchGate publication ID

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