(Q28574924)

31 January 2017

title

Phosphorylation of the Ras-GRF1 exchange factor at Ser916/898 reveals activation of Ras signaling in the cerebral cortex (English)

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31 January 2017

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Huibin Yang

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31 January 2017

Desma Cooley

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31 January 2017

Julie E. Legakis

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31 January 2017

Qingyuan Ge

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31 January 2017

Rodrigo Andrade

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31 January 2017

Raymond R. Mattingly

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31 January 2017

language of work or name

English

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publication date

11 April 2003

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Journal of Biological Chemistry

31 January 2017

published in

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31 January 2017

volume

278

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31 January 2017

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31 January 2017

page(s)

13278–13285

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https://api.crossref.org/works/10.1074%2FJBC.M209805200

31 January 2017

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Membrane depolarization and calcium influx stimulate MEK and MAP kinase via activation of Ras.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209805200

Proteins regulating Ras and its relatives

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209805200

A growing family of guanine nucleotide exchange factors is responsible for activation of ras-family GTPases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209805200

Identification and characterization of the neurofibromatosis type 1 protein product

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209805200

A cytoplasmic protein stimulates normal N-ras p21 GTPase, but does not affect oncogenic mutants

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209805200

Molecular cloning of cDNAs encoding a guanine-nucleotide-releasing factor for Ras p21

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209805200

Regulated and constitutive activity by CDC25Mm (GRF), a Ras-specific exchange factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209805200

Localization of the cellular expression pattern of cdc25NEF and ras in the juvenile rat brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209805200

Expression of two different products of CDC25Mm, a mammalian Ras activator, during development of mouse brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209805200

Ras-GRF, the activator of Ras, is expressed preferentially in mature neurons of the central nervous system.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209805200

The Ras Guanine nucleotide Exchange Factor CDC25Mm is present at the synaptic junction.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209805200

A synaptic Ras-GTPase activating protein (p135 SynGAP) inhibited by CaM kinase II

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209805200

Ras and Rap control AMPA receptor trafficking during synaptic plasticity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209805200

Toward a molecular definition of long-term memory storage

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209805200

Some forms of cAMP-mediated long-lasting potentiation are associated with release of BDNF and nuclear translocation of phospho-MAP kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209805200

A role for the Ras signalling pathway in synaptic transmission and long-term memory

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209805200

Hippocampus-dependent learning and memory is impaired in mice lacking the Ras-guanine-nucleotide releasing factor 1 (Ras-GRF1).

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209805200

Phosphorylation-dependent activation of the Ras-GRF/CDC25Mm exchange factor by muscarinic receptors and G-protein beta gamma subunits

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209805200

Activation of the Ras-GRF/CDC25Mm exchange factor by lysophosphatidic acid

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209805200

The N-terminal pleckstrin, coiled-coil, and IQ domains of the exchange factor Ras-GRF act cooperatively to facilitate activation by calcium

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209805200

Phosphorylation of serine 916 of Ras-GRF1 contributes to the activation of exchange factor activity by muscarinic receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209805200

Muscarinic receptors transform NIH 3T3 cells through a Ras-dependent signalling pathway inhibited by the Ras-GTPase-activating protein SH3 domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209805200

Association of Sos Ras exchange protein with Grb2 is implicated in tyrosine kinase signal transduction and transformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209805200

Ras-GRF activates Ha-Ras, but not N-Ras or K-Ras 4B, protein in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209805200

Identification of a family of muscarinic acetylcholine receptor genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209805200

Role of the Rab3A-binding domain in targeting of rabphilin-3A to vesicle membranes of PC12 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209805200

Low concentrations of inorganic mercury inhibit Ras activation during T cell receptor-mediated signal transduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209805200

Regulation of Sos activity by intramolecular interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209805200

Mechanisms through which Sos-1 coordinates the activation of Ras and Rac.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209805200

Okadaic acid inhibits angiotensin II stimulation of Ins(1,4,5)P3 and calcium signalling in rat hepatocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209805200

Is the Ras-MAPK signalling pathway necessary for long-term memory formation?

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209805200

Involvement of CDC25Mm/Ras-GRF1-dependent signaling in the control of neuronal excitability

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209805200

Imprinted gene in postnatal growth role

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209805200

Mechanism for the learning deficits in a mouse model of neurofibromatosis type 1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209805200

Molecular neurobiology of human cognition.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209805200

Sites of phosphorylation by protein kinase A in CDC25Mm/GRF1, a guanine nucleotide exchange factor for Ras.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209805200

Cloning and characterization of Ras-GRF2, a novel guanine nucleotide exchange factor for Ras

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209805200

Targeted disruption of Ras-Grf2 shows its dispensability for mouse growth and development.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209805200

The cholinergic hypothesis of geriatric memory dysfunction

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209805200

Cholinergic agonists and the treatment of Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209805200

Protein kinase phosphorylation site sequences and consensus specificity motifs: tabulations

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209805200

Activity-dependent interaction of the intracellular domain of rat trkA with intermediate filament proteins, the beta-6 proteasomal subunit, Ras-GRF1, and the p162 subunit of eIF3

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209805200

G protein beta gamma subunit-dependent Rac-guanine nucleotide exchange activity of Ras-GRF1/CDC25(Mm)

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209805200

CDC25(Mm)/Ras-GRF1 regulates both Ras and Rac signaling pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209805200

Induction of rac-guanine nucleotide exchange activity of Ras-GRF1/CDC25(Mm) following phosphorylation by the nonreceptor tyrosine kinase Src.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209805200

Stimulation of Ras guanine nucleotide exchange activity of Ras-GRF1/CDC25(Mm) upon tyrosine phosphorylation by the Cdc42-regulated kinase ACK1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209805200

The Rho family GTPase Cdc42 regulates the activation of Ras/MAP kinase by the exchange factor Ras-GRF.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209805200

Maintenance of CDC42 GDP-bound state by Rho-GDI inhibits MAP kinase activation by the exchange factor Ras-GRF. evidence for Ras-GRF function being inhibited by Cdc42-GDP but unaffected by CDC42-GTP.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209805200

Ca2+/calmodulin-dependent protein kinase II regulates Tiam1 by reversible protein phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209805200

Activation of C3G guanine nucleotide exchange factor for Rap1 by phosphorylation of tyrosine 504.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209805200

RasGRP, a Ras guanyl nucleotide- releasing protein with calcium- and diacylglycerol-binding motifs

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209805200

Direct stimulation of the guanine nucleotide exchange activity of p115 RhoGEF by Galpha13

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209805200

Direct binding of the beta1 adrenergic receptor to the cyclic AMP-dependent guanine nucleotide exchange factor CNrasGEF leads to Ras activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209805200

Ras-specific exchange factor GRF: oligomerization through its Dbl homology domain and calcium-dependent activation of Raf

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209805200

Interaction of Rac exchange factors Tiam1 and Ras-GRF1 with a scaffold for the p38 mitogen-activated protein kinase cascade

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209805200

Down-regulation of growth factor-stimulated MAP kinase signaling in cytotoxic drug-resistant human neuroblastoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209805200

Mutations within the Ran/TC4 GTPase. Effects on regulatory factor interactions and subcellular localization

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209805200

Microinjection of the ras oncogene protein into PC12 cells induces morphological differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209805200

Analysis of the secondary structure of the catalytic domain of mouse Ras exchange factor CDC25Mm

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209805200

Epidermal growth factor regulates p21ras through the formation of a complex of receptor, Grb2 adapter protein, and Sos nucleotide exchange factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209805200

Raf-1 Is Involved in the Regulation of the Interaction between Guanine Nucleotide Exchange Factor and Ha-Ras

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209805200

21 January 2018

Identifiers

DOI

10.1074/JBC.M209805200

1 reference

31 January 2017

1 reference