(Q28507307)

24 January 2017

title

A novel signaling intermediate, SHEP1, directly couples Eph receptors to R-Ras and Rap1A (English)

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24 January 2017

main subject

SH2 domain containing 3C

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GOA release 2020-03-11

V. C. Dodelet

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24 January 2017

C. Pazzagli

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24 January 2017

A. H. Zisch

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24 January 2017

C. A. Hauser

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24 January 2017

E. B. Pasquale

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24 January 2017

language of work or name

English

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publication date

5 November 1999

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Journal of Biological Chemistry

24 January 2017

published in

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24 January 2017

volume

274

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24 January 2017

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24 January 2017

page(s)

31941–31946

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The Eph family in the patterning of neural development

24 January 2017

cites work

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The ephrins and Eph receptors in neural development

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Eph family transmembrane ligands can mediate repulsive guidance of trunk neural crest migration and motor axon outgrowth

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In vitro guidance of retinal ganglion cell axons by RAGS, a 25 kDa tectal protein related to ligands for Eph receptor tyrosine kinases

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Lerk2 (ephrin-B1) is a collapsing factor for a subset of cortical growth cones and acts by a mechanism different from AL-1 (ephrin-A5).

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AL-1-induced growth cone collapse of rat cortical neurons is correlated with REK7 expression and rearrangement of the actin cytoskeleton

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Eph receptors discriminate specific ligand oligomers to determine alternative signaling complexes, attachment, and assembly responses

21 January 2018

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Surface densities of ephrin-B1 determine EphB1-coupled activation of cell attachment through alphavbeta3 and alpha5beta1 integrins

21 January 2018

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Complex formation between EphB2 and Src requires phosphorylation of tyrosine 611 in the EphB2 juxtamembrane region

21 January 2018

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Ligand activation of ELK receptor tyrosine kinase promotes its association with Grb10 and Grb2 in vascular endothelial cells

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Nck recruitment to Eph receptor, EphB1/ELK, couples ligand activation to c-Jun kinase

21 January 2018

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Juxtamembrane tyrosine residues couple the Eph family receptor EphB2/Nuk to specific SH2 domain proteins in neuronal cells

21 January 2018

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Characterization of a novel Src-like adapter protein that associates with the Eck receptor tyrosine kinase

21 January 2018

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Ras-Raf interaction: two-hybrid analysis

21 January 2018

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The multidomain protein Trio binds the LAR transmembrane tyrosine phosphatase, contains a protein kinase domain, and has separate rac-specific and rho-specific guanine nucleotide exchange factor domains

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Identification of BCAR3 by a random search for genes involved in antiestrogen resistance of human breast cancer cells

21 January 2018

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Unified Nomenclature for Eph Family Receptors and Their Ligands, the Ephrins

21 January 2018

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Guanine nucleotide exchange factors: activators of the Ras superfamily of proteins

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Integrin activation by R-ras.

21 January 2018

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Activation of R-Ras by Ras-guanine nucleotide-releasing factor

21 January 2018

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R-Ras is regulated by activators and effectors distinct from those that control Ras function

21 January 2018

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21 January 2018

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21 January 2018

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Faciogenital dysplasia protein (FGD1) and Vav, two related proteins required for normal embryonic development, are upstream regulators of Rho GTPases

21 January 2018

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Defective signalling through the T- and B-cell antigen receptors in lymphoid cells lacking the vav proto-oncogene

21 January 2018

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Defective antigen receptor-mediated proliferation of B and T cells in the absence of Vav.

21 January 2018

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The N-terminal moiety of CDC25(Mm), a GDP/GTP exchange factor of Ras proteins, controls the activity of the catalytic domain. Modulation by calmodulin and calpain.

21 January 2018

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Regulation of Sos activity by intramolecular interactions

21 January 2018

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N terminus of Sos1 Ras exchange factor: critical roles for the Dbl and pleckstrin homology domains

21 January 2018

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Phosphotyrosine-dependent activation of Rac-1 GDP/GTP exchange by the vav proto-oncogene product

21 January 2018

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Activation of C3G guanine nucleotide exchange factor for Rap1 by phosphorylation of tyrosine 504.

21 January 2018

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The structural basis of the activation of Ras by Sos

21 January 2018

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Structure of the Sec7 domain of the Arf exchange factor ARNO

21 January 2018

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Structure of the guanine nucleotide exchange factor Sec7 domain of human arno and analysis of the interaction with ARF GTPase

21 January 2018

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R-Ras promotes apoptosis caused by growth factor deprivation via a Bcl-2 suppressible mechanism.

21 January 2018

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NSP1 defines a novel family of adaptor proteins linking integrin and tyrosine kinase receptors to the c-Jun N-terminal kinase/stress-activated protein kinase signaling pathway

21 January 2018

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p130Cas, a substrate associated with v-Src and v-Crk, localizes to focal adhesions and binds to focal adhesion kinase

21 January 2018

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Identification of p130Cas as a mediator of focal adhesion kinase-promoted cell migration

21 January 2018

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Cell adhesion regulates the interaction between the docking protein p130(Cas) and the 14-3-3 proteins

21 January 2018

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Prediction of the coding sequences of unidentified human genes. VI. The coding sequences of 80 new genes (KIAA0201-KIAA0280) deduced by analysis of cDNA clones from cell line KG-1 and brain

21 January 2018

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21 January 2018

Identifiers

DOI

10.1074/JBC.274.45.31941

0 references

1 reference